EXHIBIT 21.1

SUBSIDIARIES OF CORONADO BIOSCIENCES, INC.

Subsidiaries of Coronado Biosciences, Inc. at December 31, 2014: 

• Altamira Bio Inc., formerly TSO Development Corporation, Inc.

• CB Pharma Acquisition Corp.

• CB Securities Corporation

• Coronado SO Co., Inc.

• Cyprium, Inc.

• Innmune Limited

• Journey Medical Corporation

Additional subsidiaries of Coronado Biosciences, Inc. formed after December 31, 2014:

• Avenue Therapeutics, Inc.

• Checkpoint Therapeutics, Inc.