-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, M38Pl/Q99vSjBkzOcog/lscp1YUN3IIuqi8BMBbeTrr/KYjwt8oI5uMY108f1C1g tKQMs2R1ovh82P3fVDwz8w== 0001193125-07-256958.txt : 20071130 0001193125-07-256958.hdr.sgml : 20071130 20071130131740 ACCESSION NUMBER: 0001193125-07-256958 CONFORMED SUBMISSION TYPE: 8-K/A PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20071025 ITEM INFORMATION: Results of Operations and Financial Condition ITEM INFORMATION: Financial Statements and Exhibits FILED AS OF DATE: 20071130 DATE AS OF CHANGE: 20071130 FILER: COMPANY DATA: COMPANY CONFORMED NAME: BRISTOL MYERS SQUIBB CO CENTRAL INDEX KEY: 0000014272 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 220790350 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 8-K/A SEC ACT: 1934 Act SEC FILE NUMBER: 001-01136 FILM NUMBER: 071277179 BUSINESS ADDRESS: STREET 1: 345 PARK AVE CITY: NEW YORK STATE: NY ZIP: 10154 BUSINESS PHONE: 2125464000 MAIL ADDRESS: STREET 1: 345 PARK AVE CITY: NEW YORK STATE: NY ZIP: 10154 FORMER COMPANY: FORMER CONFORMED NAME: BRISTOL MYERS CO DATE OF NAME CHANGE: 19891012 8-K/A 1 d8ka.htm AMENDMENT NO. 1 TO FORM 8-K Amendment No. 1 to Form 8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K/A

(Amendment No. 1)

CURRENT REPORT

Pursuant to Section 13 OR 15(d) of The Securities Exchange Act Of 1934

Date of Report (Date of earliest event reported): October 25, 2007

BRISTOL-MYERS SQUIBB COMPANY

(Exact Name of Registrant as Specified in its Charter)

 

Delaware   1-1136   22-079-0350

(State or Other

Jurisdiction of

Incorporation)

 

(Commission File

Number)

 

(IRS Employer

Identification

Number)

345 Park Avenue

New York, NY, 10154

(Address of Principal Executive Office)

Registrant’s telephone number, including area code: (212) 546-4000

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

¨ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 



Item 2.02. Results of Operations and Financial Condition.

On October 25, 2007, Bristol-Myers Squibb Company (the “Company”) filed a Form 8-K furnishing its press release that announced the Company’s financial results for the third quarter of 2007 and incorporating it therein by reference. Also furnished and incorporated by reference as Exhibit 99.2 was certain supplemental information posted on the Company’s website at www.bms.com. This supplemental information has been revised to include net sales, months on hand, and estimated demand information for key products as of September 30, 2007 for the Company’s International Pharmaceutical, Nutritionals and Other Health Care reporting segments. Net sales and months on hand information is also provided as of June 30, 2007, September 30, 2006 and June 30, 2006. The revised supplemental information is furnished and incorporated by reference as Exhibit 99.2 to this Form 8-K/A.

 

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.

 

99.2.    Certain supplemental information posted on Bristol-Myers Squibb Company’s website at www.bms.com


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

    BRISTOL-MYERS SQUIBB COMPANY
Dated: November 30, 2007     By:   /s/ Sandra Leung
      Name:   Sandra Leung
      Title:   Senior Vice President and General Counsel


EXHIBIT INDEX

 

Exhibit No.   

Description

99.2    Certain supplemental information posted on Bristol-Myers Squibb Company’s website at www.bms.com
EX-99.2 2 dex992.htm CERTAIN SUPPLEMENTAL INFORMATION Certain supplemental information

Exhibit 99.2

BRISTOL-MYERS SQUIBB COMPANY

NET SALES

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

     2006     2007    % Change  

Net Sales

  

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

    Year    

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

   Year    Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Pharmaceuticals

   $ 3,700     $ 3,859     $ 7,559     $ 3,154     $ 10,713     $ 3,148     $ 13,861     $ 3,457     $ 3,851     $ 7,308     $ 3,926     $ 11,234           24 %   5 %

US Pharmaceuticals

     2,064       2,197       4,261       1,609       5,870       1,501       7,371       1,932       2,235       4,167       2,295       6,462           43 %   10 %

Primary Care

     1,409       1,441       2,850       819       3,669       648       4,317       1,090       1,344       2,434       1,363       3,797           66 %   3 %

Oncology/Virology

     419       458       877       494       1,371       525       1,896       504       511       1,015       539       1,554           9 %   13 %

Neuroscience

     231       280       511       262       773       297       1,070       298       327       625       336       961           28 %   24 %

Immunoscience

     5       18       23       34       57       31       88       40       53       93       57       150           68 %   163 %

Europe and Middle East Medicines

     1,024       1,000       2,024       886       2,910       934       3,844       916       939       1,855       944       2,799           7 %   -4 %

Latin America/Canada

     288       303       591       300       891       306       1,197       297       311       608       331       939           10 %   5 %

Asia/Pacific Medicines

     279       320       599       318       917       349       1,266       289       333       622       319       941           —       3 %

Health Care Group

     976       1,012       1,988       1,000       2,988       1,065       4,053       1,019       1,077       2,096       1,124       3,220           12 %   8 %

Nutritionals

     565       582       1,147       582       1,729       618       2,347       606       620       1,226       675       1,901           16 %   10 %

Other Health Care

     411       430       841       418       1,259       447       1,706       413       457       870       449       1,319           7 %   5 %

ConvaTec

     230       262       492       265       757       291       1,048       254       286       540       292       832           10 %   10 %

Medical Imaging

     181       168       349       153       502       156       658       159       171       330       157       487           3 %   -3 %

Total Company

   $ 4,676     $ 4,871     $ 9,547     $ 4,154     $ 13,701     $ 4,213     $ 17,914     $ 4,476     $ 4,928     $ 9,404     $ 5,050     $ 14,454           22 %   5 %
     2006     2007    Basis Point
Change
 

% of Total Sales

  

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

    Year    

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

   Year    Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Pharmaceuticals

     79.1 %     79.2 %     79.2 %     75.9 %     78.2 %     74.7 %     77.4 %     77.2 %     78.1 %     77.7 %     77.7 %     77.7 %         180     (50 )

US Pharmaceuticals

     44.1 %     45.1 %     44.6 %     38.7 %     42.8 %     35.6 %     41.1 %     43.2 %     45.4 %     44.3 %     45.4 %     44.7 %         670     190  

Primary Care

     30.1 %     29.6 %     29.9 %     19.7 %     26.8 %     15.4 %     24.1 %     24.4 %     27.3 %     25.9 %     26.9 %     26.3 %         720     (50 )

Oncology/Virology

     9.0 %     9.4 %     9.2 %     11.9 %     10.0 %     12.5 %     10.5 %     11.3 %     10.4 %     10.8 %     10.7 %     10.8 %         (120 )   80  

Neuroscience

     4.9 %     5.7 %     5.3 %     6.3 %     5.6 %     7.0 %     6.0 %     6.7 %     6.6 %     6.6 %     6.7 %     6.6 %         40     100  

Immunoscience

     0.1 %     0.4 %     0.2 %     0.8 %     0.4 %     0.7 %     0.5 %     0.8 %     1.1 %     1.0 %     1.1 %     1.0 %         30     60  

Europe and Middle East Medicines

     21.9 %     20.5 %     21.2 %     21.3 %     21.2 %     22.2 %     21.5 %     20.5 %     19.1 %     19.7 %     18.7 %     19.4 %         (260 )   (180 )

Latin America/Canada

     6.2 %     6.2 %     6.2 %     7.2 %     6.5 %     7.3 %     6.7 %     6.6 %     6.3 %     6.5 %     6.6 %     6.5 %         (60 )   —    

Asia/Pacific Medicines

     6.0 %     6.6 %     6.3 %     7.7 %     6.7 %     8.3 %     7.1 %     6.5 %     6.8 %     6.6 %     6.3 %     6.5 %         (140 )   (20 )

Health Care Group

     20.9 %     20.8 %     20.8 %     24.1 %     21.8 %     25.3 %     22.6 %     22.8 %     21.9 %     22.3 %     22.3 %     22.3 %         (180 )   50  

Nutritionals

     12.1 %     12.0 %     12.0 %     14.0 %     12.6 %     14.7 %     13.1 %     13.5 %     12.6 %     13.0 %     13.4 %     13.2 %         (60 )   60  

Other Health Care

     8.8 %     8.8 %     8.8 %     10.1 %     9.2 %     10.6 %     9.5 %     9.3 %     9.3 %     9.3 %     8.9 %     9.1 %         (120 )   (10 )

ConvaTec

     4.9 %     5.4 %     5.2 %     6.4 %     5.5 %     6.9 %     5.8 %     5.7 %     5.8 %     5.8 %     5.8 %     5.7 %         (60 )   20  

Medical Imaging

     3.9 %     3.4 %     3.6 %     3.7 %     3.7 %     3.7 %     3.7 %     3.6 %     3.5 %     3.5 %     3.1 %     3.4 %         (60 )   (30 )

Total Company

     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %          

* In Excess of +/- 200%

 

1


BRISTOL-MYERS SQUIBB COMPANY

SEGMENT SALES AND COMPOSITION OF CHANGE IN SALES FOR TOTAL COMPANY

FOR THE PERIOD ENDED SEPTEMBER 30, 2007

($ in millions)

QUARTER-TO-DATE

 

     Pharmaceuticals     Nutritionals     ConvaTec     Medical
Imaging
   

Total

Company

 

Price Increases/(Decreases)

     4 %     3 %     -1 %     8 %     4 %

Foreign Exchange

     3 %     4 %     5 %     1 %     3 %

Volume

     17 %     9 %     6 %     -6 %     15 %
                                        

Total Change

     24 %     16 %     10 %     3 %     22 %
                                        

Total 2007 Period to Date Sales

   $ 3,926     $ 675     $ 292     $ 157     $ 5,050  

Total 2006 Period to Date Sales

   $ 3,154     $ 582     $ 265     $ 153     $ 4,154  

 

YEAR-TO-DATE

          
     Pharmaceuticals     Nutritionals     ConvaTec     Medical
Imaging
   

Total

Company

 

Price Increases/(Decreases)

     2 %     2 %     -1 %     1 %     1 %

Foreign Exchange

     2 %     3 %     5 %     1 %     2 %

Volume

     1 %     5 %     6 %     -5 %     2 %
                                        

Total Change

     5 %     10 %     10 %     -3 %     5 %
                                        

Total 2007 Period to Date Sales

   $ 11,234     $ 1,901     $ 832     $ 487     $ 14,454  

Total 2006 Period to Date Sales

   $ 10,713     $ 1,729     $ 757     $ 502     $ 13,701  

 

2


BRISTOL-MYERS SQUIBB COMPANY

CONSOLIDATED STATEMENT OF EARNINGS

($ in millions, except per share amounts)

 

     2006     2007    % Change  
     

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

    Year     1st
Qtr
   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months     4th
Qtr
   Year    Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Net Sales

   $ 4,676     $ 4,871     $ 9,547     $ 4,154     $ 13,701     $ 4,213     $ 17,914     $ 4,476     $ 4,928     $ 9,404     $ 5,050     $ 14,454           22 %   5 %

Cost of products sold

     1,476       1,568       3,044       1,465       4,509       1,447       5,956       1,392       1,549       2,941       1,622       4,563           11 %   1 %

Marketing, selling and administrative

     1,238       1,181       2,419       1,189       3,608       1,311       4,919       1,158       1,209       2,367       1,214       3,581           2 %   -1 %

Advertising and product promotion

     295       352       647       286       933       418       1,351       269       368       637       351       988           23 %   6 %

Research and development

     750       740       1,490       756       2,246       821       3,067       807       778       1,585       827       2,412           9 %   7 %

Provision for restructuring, net

     1       3       4       2       6       53       59       37       7       44       —         44           -100 %   *  

Litigation (income)/expense, net

     (21 )     (14 )     (35 )     (9 )     (44 )     346       302       —         14       14       —         14           100 %   132 %

Gain on sale of product assets

     (200 )     —         (200 )     —         (200 )     —         (200 )     —         (26 )     (26 )     (247 )     (273 )         —       -37 %

Equity in net income of affiliates

     (93 )     (125 )     (218 )     (118 )     (336 )     (138 )     (474 )     (126 )     (128 )     (254 )     (139 )     (393 )         -18 %   -17 %

Other expense/(income), net

     37       56       93       (34 )     59       240       299       22       —         22       11       33           132 %   -44 %
                                                                                                                      

Total expenses

     3,483       3,761       7,244       3,537       10,781       4,498       15,279       3,559       3,771       7,330       3,639       10,969           3 %   2 %
                                                                                                                      

Earnings/(Loss) Before Minority Interest and Income Taxes

     1,193       1,110       2,303       617       2,920       (285 )     2,635       917       1,157       2,074       1,411       3,485           129 %   19 %

Provision/(Benefit) for income taxes

     328       256       584       193       777       (167 )     610       86       257       343       342       685           77 %   -12 %

Minority interest, net of taxes

     151       187       338       86       424       16       440       141       194       335       211       546           145 %   29 %
                                                                                                                      

Net Earnings/(Loss)

   $ 714     $ 667     $ 1,381     $ 338     $ 1,719     ($ 134 )   $ 1,585     $ 690     $ 706     $ 1,396     $ 858     $ 2,254           154 %   31 %
                                                                                                                      

Interest expense on conversion of convertible debt bonds, net of tax

     8       8       16       9       25       —   (a)     —   (b)     9       9       18       10       28            
                                                                                                                      

Net Earnings/(Loss) used for diluted earnings per common share calculation

   $ 722     $ 675     $ 1,397     $ 347     $ 1,744     ($ 134 )(a)   $ 1,585 (b)   $ 699     $ 715     $ 1,414     $ 868     $ 2,282            
                                                                                                                      

Diluted Earnings/(Loss) per Common Share**

   $ 0.36     $ 0.34     $ 0.70     $ 0.17     $ 0.88     ($ 0.07 )(a)   $ 0.81 (b)   $ 0.35     $ 0.36     $ 0.71     $ 0.43     $ 1.14           153 %   30 %

Average Common Shares Outstanding—Diluted

     1,988       1,994       1,992       1,992       1,991       1,961 (a)     1,963 (b)     1,997       2,006       2,002       2,012       2,005           1 %   1 %

Dividends declared per common share

   $ 0.28     $ 0.28     $ 0.56     $ 0.28     $ 0.84     $ 0.28     $ 1.12     $ 0.28     $ 0.28     $ 0.56     $ 0.28     $ 0.84           —       —    
     2006     2007    Basis Point
Change
 
% of Net Sales   

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

    Year    

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

   Year   

Qtr

vs.
Qtr

    YTD
vs.
YTD
 

Gross Margin

     68.4 %     67.8 %     68.1 %     64.7 %     67.1 %     65.7 %     66.8 %     68.9 %     68.6 %     68.7 %     67.9 %     68.4 %         320     130  

Cost of products sold

     31.6 %     32.2 %     31.9 %     35.3 %     32.9 %     34.3 %     33.2 %     31.1 %     31.4 %     31.3 %     32.1 %     31.6 %         (320 )   (130 )

Marketing, selling and administrative

     26.5 %     24.2 %     25.3 %     28.6 %     26.3 %     31.1 %     27.5 %     25.9 %     24.5 %     25.2 %     24.0 %     24.8 %         (460 )   (150 )

Advertising and product promotion

     6.3 %     7.2 %     6.8 %     6.9 %     6.8 %     9.9 %     7.5 %     6.0 %     7.5 %     6.8 %     7.0 %     6.8 %         10     0  

Research and development

     16.0 %     15.2 %     15.6 %     18.2 %     16.4 %     19.5 %     17.1 %     18.0 %     15.8 %     16.9 %     16.4 %     16.7 %         (180 )   30  

Total expenses

     74.5 %     77.2 %     75.9 %     85.1 %     78.7 %     106.8 %     85.3 %     79.5 %     76.5 %     77.9 %     72.1 %     75.9 %         (1,300 )   (280 )

Earnings/(Loss) Before Minority Interest and Income Taxes

     25.5 %     22.8 %     24.1 %     14.9 %     21.3 %     -6.8 %     14.7 %     20.5 %     23.5 %     22.1 %     27.9 %     24.1 %         1,300     280  

Net Earnings/(Loss)

     15.3 %     13.7 %     14.5 %     8.1 %     12.5 %     -3.2 %     8.8 %     15.4 %     14.3 %     14.8 %     17.0 %     15.6 %         890     310  

Other Ratios

                                  

Effective Tax Rate

     27.5 %     23.1 %     25.4 %     31.3 %     26.6 %     58.6 %     23.1 %     9.4 %     22.2 %     16.5 %     24.2 %     19.7 %         (710 )   (690 )
     2006     2007    % Change  
Other (Income)/Expense, net   

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

    Year    

1st

Qtr

   

2nd

Qtr

    6 Months    

3rd

Qtr

    9 Months    

4th

Qtr

   Year    Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Interest expense

   $ 116     $ 124     $ 240     $ 130     $ 370     $ 128     $ 498     $ 109     $ 107     $ 216     $ 109     $ 325           -16 %   -12 %

Interest income

     (62 )     (65 )     (127 )     (74 )     (201 )     (73 )     (274 )     (53 )     (62 )     (115 )     (69 )     (184 )         7 %   8 %

Foreign exchange transaction (gains)/losses

     (12 )     23       11       (11 )     —         6       6       8       (5 )     3       24       27             *   —    

Other, net

     (5 )     (26 )     (31 )     (79 )     (110 )     179       69       (42 )     (40 )     (82 )     (53 )     (135 )         33 %   -23 %
                                                                                                                      
   $ 37     $ 56     $ 93     $ (34 )   $ 59     $ 240     $ 299     $ 22     $ 0     $ 22     $ 11     $ 33           132 %   -44 %

* in excess of +/- 200%
** quarterly amounts may not add to the year-to-date totals due to rounding of individual calculations.
(a) as a result of the Q4 2006 net loss, Diluted Average Common Shares Outstanding and Loss per Common Share are equal to Basic Average Common Shares Outstanding and Loss per Common Share.
(b) assumed interest amount and the assumed conversion of convertible debt are not used for Diluted Earnings per Common Share calculation as the impact of convertible debt is anti-dilutive.

 

3


BRISTOL-MYERS SQUIBB COMPANY

WORLDWIDE NET SALES BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

    2006    2007   %
Change
 
    1st
Qtr
   2nd
Qtr
   6 Months    3rd
Qtr
   9 Months    4th
Qtr
   Year    1st
Qtr
   2nd
Qtr
   6 Months    3rd
Qtr
   9 Months    4th
Qtr
   Year  

Qtr

vs.

Qtr

   

YTD

vs.

YTD

 

Total Company

  $ 4,676    $ 4,871    $ 9,547    $ 4,154    $ 13,701    $ 4,213    $ 17,914    $ 4,476    $ 4,928    $ 9,404    $ 5,050    $ 14,454         22 %   5 %

PHARMACEUTICALS

    3,700      3,859      7,559      3,154      10,713      3,148      13,861      3,457      3,851      7,308      3,926      11,234         24 %   5 %

Cardiovascular

    1,917      1,907      3,824      1,239      5,063      1,093      6,156      1,475      1,763      3,238      1,793      5,031         45 %   -1 %

Plavix

    986      1,145      2,131      630      2,761      496      3,257      938      1,189      2,127      1,254      3,381         99 %   22 %

Pravachol

    536      323      859      192      1,051      146      1,197      135      132      267      86      353         -55 %   -66 %

Avapro/ Avalide

    233      280      513      277      790      307      1,097      270      297      567      309      876         12 %   11 %

Coumadin

    55      55      110      53      163      57      220      46      52      98      50      148         -6 %   -9 %

Virology

    468      524      992      532      1,524      580      2,104      590      608      1,198      647      1,845         22 %   21 %

Reyataz

    207      236      443      233      676      255      931      263      254      517      273      790         17 %   17 %

Sustiva Franchise***

    175      193      368      201      569      222      791      226      233      459      237      696         18 %   22 %

Baraclude

    11      14      25      22      47      36      83      45      59      104      72      176         *     *  

Oncology

    361      401      762      399      1,161      394      1,555      355      360      715      402      1,117         1 %   -4 %

Erbitux

    138      172      310      175      485      167      652      160      162      322      185      507         6 %   5 %

Taxol

    147      149      296      137      433      130      563      111      95      206      102      308         -26 %   -29 %

Sprycel

    —        —        —        11      11      14      25      21      35      56      46      102         *     *  

Affective (Psychiatric) Disorders

    323      376      699      354      1,053      404      1,457      408      458      866      467      1,333         32 %   27 %

Abilify**

    283      324      607      313      920      362      1,282      366      412      778      420      1,198         34 %   30 %

Immunoscience

    5      18      23      34      57      32      89      41      55      96      60      156         76 %   174 %

Orencia

    5      18      23      34      57      32      89      41      55      96      60      156         76 %   174 %

Other Pharmaceuticals

                                            

Efferalgan

    68      62      130      62      192      74      266      81      69      150      71      221         15 %   15 %

HEALTH CARE GROUP

    976      1,012      1,988      1,000      2,988      1,065      4,053      1,019      1,077      2,096      1,124      3,220         12 %   8 %

NUTRITIONALS

    565      582      1,147      582      1,729      618      2,347      606      620      1,226      675      1,901         16 %   10 %

Enfamil

    237      253      490      246      736      271      1,007      254      267      521      281      802         14 %   9 %

Enfagrow

    67      59      126      69      195      67      262      72      70      142      74      216         7 %   11 %

OTHER HEALTH CARE

    411      430      841      418      1,259      447      1,706      413      457      870      449      1,319         7 %   5 %

CONVATEC

    230      262      492      265      757      291      1,048      254      286      540      292      832         10 %   10 %

Ostomy

    123      141      264      139      403      151      554      130      150      280      147      427         6 %   6 %

Wound Therapeutics

    98      107      205      113      318      123      441      107      119      226      126      352         12 %   11 %

MEDICAL IMAGING

    181      168      349      153      502      156      658      159      171      330      157      487         3 %   -3 %

Cardiolite

    103      105      208      97      305      103      408      99      106      205      99      304         2 %   —    

* In excess of +/- 200%
** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** Beginning in the third quarter of 2006, Sustiva Franchise includes sales of Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc.

 

4


BRISTOL-MYERS SQUIBB COMPANY

DOMESTIC* NET SALES BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

     2006    2007   %
Change
   

% Change in U.S.

Total Prescription****

 
    

1st

Qtr

   2nd
Qtr
   6 Months    3rd
Qtr
   9 Months    4th
Qtr
   Year    1st
Qtr
   2nd
Qtr
   6 Months    3rd
Qtr
   9 Months   

4th

Qtr

   Year  

Qtr

vs.

Qtr

   

YTD

vs.

YTD

   

Qtr

vs.

Qtr

   

YTD

vs.

YTD

 

Total Company

   $ 2,638    $ 2,806    $ 5,444    $ 2,170    $ 7,614    $ 2,115    $ 9,729    $ 2,505    $ 2,830    $ 5,335    $ 2,920    $ 8,255         35 %   8 %    

PHARMACEUTICALS

     2,076      2,205      4,281      1,619      5,900      1,517      7,417      1,944      2,243      4,187      2,302      6,489         42 %   10 %    

Cardiovascular

     1,341      1,330      2,671      752      3,423      616      4,039      1,045      1,279      2,324      1,316      3,640         75 %   6 %    

Plavix

     850      988      1,838      474      2,312      343      2,655      787      1,015      1,802      1,080      2,882         128 %   25 %   86 %   6 %

Pravachol

     302      128      430      73      503      50      553      57      47      104      17      121         -77 %   -76 %   -77 %   -82 %

Avapro/Avalide

     139      167      306      159      465      182      647      163      170      333      176      509         11 %   9 %   -4 %   -3 %

Coumadin

     47      46      93      45      138      48      186      38      43      81      40      121         -11 %   -12 %   -15 %   -16 %

Virology

     259      270      529      292      821      327      1,148      319      323      642      328      970         12 %   18 %    

Reyataz

     119      122      241      129      370      144      514      143      138      281      141      422         9 %   14 %   10 %   13 %

Sustiva Franchise*****

     108      115      223      128      351      144      495      144      147      291      151      442         18 %   26 %   19 %   23 %

Baraclude

     9      9      18      14      32      18      50      17      20      37      22      59         57 %   84 %   71 %   86 %

Oncology

     159      187      346      201      547      195      742      182      187      369      208      577         3 %   5 %    

Erbitux

     136      172      308      173      481      165      646      158      160      318      183      501         6 %   4 %   N/A     N/A  

Taxol

     4      4      8      2      10      2      12      4      4      8      1      9         -50 %   -10 %   N/A     N/A  

Sprycel

     —        —        —        11      11      11      22      10      14      24      17      41         55 %   * **   N/A     N/A  

Affective (Psychiatric) Disorders

     237      286      523      266      789      302      1,091      305      333      638      346      984         30 %   25 %    

Abilify**

     231      267      498      260      758      294      1,052      293      322      615      329      944         27 %   25 %   10 %   12 %

Immunoscience

     5      18      23      34      57      31      88      40      53      93      57      150         68 %   163 %    

Orencia

     5      18      23      34      57      31      88      40      53      93      57      150         68 %   163 %   N/A     N/A  

Other Pharmaceuticals

                                                 

Efferalgan

     —        —        —        —        —        —        —        —        —        —        —        —           —       —       N/A     N/A  

HEALTH CARE GROUP

     478      508      986      482      1,468      527      1,995      488      511      999      529      1,528         10 %   4 %   N/A     N/A  

NUTRITIONALS

     247      282      529      267      796      295      1,091      274      275      549      304      853         14 %   7 %    

Enfamil

     155      174      329      169      498      190      688      171      177      348      195      543         15 %   9 %   N/A     N/A  

Enfagrow

     —        —        —        —        —        —        —        —        —        —        —        —           —       —       N/A     N/A  

OTHER HEALTH CARE

     231      226      457      215      672      232      904      214      236      450      225      675         5 %   —        

CONVATEC

     73      85      158      84      242      101      343      78      93      171      94      265         12 %   10 %    

Ostomy

     34      41      75      39      114      45      159      34      41      75      42      117         8 %   3 %   N/A     N/A  

Wound Therapeutics

     30      34      64      36      100      43      143      32      36      68      38      106         6 %   6 %   N/A     N/A  

MEDICAL IMAGING

     158      141      299      131      430      131      561      136      143      279      131      410         —       -5 %    

Cardiolite

     91      91      182      86      268      90      358      87      92      179      88      267         2 %   —       N/A     N/A  

* This table presents Total Company sales on a legal entity source basis and segment and product sales on a country management reported basis. As a result, the sum of segment sales does not tie to Total Company sales.
** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** In excess of +/- 200%
**** The estimated total U.S. prescription change for the retail and mail order channels are calculated based on Next-Generation Prescription Services (NGPS) version 2.0 data on a weighted-average basis. NGPS data is provided by IMS Health, a supplier of market research for the pharmaceutical industry. The weighted-average basis reflects the fact that mail order prescriptions include a greater volume of product supplied compared to retail prescriptions, which on average are 90 days for mail order and 30 days for retail. The calculation is derived by multiplying NGPS mail order prescription data by a factor that approximates three and adding to this the NGPS retail prescriptions.
***** Beginning in the third quarter of 2006, Sustiva Franchise includes sales of Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc. The change in U.S. total prescriptions growth for the Sustiva Franchise includes both branded Sustiva and Atripla prescription units.

 

5


BRISTOL-MYERS SQUIBB COMPANY

INTERNATIONAL* NET SALES BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

     2006    2007    % Change  
    

1st

Qtr

  

2nd

Qtr

   6 Months   

3rd

Qtr

   9 Months   

4th

Qtr

   Year   

1st

Qtr

  

2nd

Qtr

   6 Months   

3rd

Qtr

   9 Months    4th
Qtr
   Year   

Qtr

vs.

Qtr

   

YTD

vs.

YTD

 

Total Company

   $ 2,038    $ 2,065    $ 4,103    $ 1,984    $ 6,087    $ 2,098    $ 8,185    $ 1,971    $ 2,098    $ 4,069    $ 2,130    $ 6,199          7 %   2 %

PHARMACEUTICALS

     1,624      1,654      3,278      1,535      4,813      1,631      6,444      1,513      1,608      3,121      1,624      4,745          6 %   -1 %

Cardiovascular

     576      577      1,153      487      1,640      477      2,117      430      484      914      477      1,391          -2 %   -15 %

Plavix

     136      157      293      156      449      153      602      151      174      325      174      499          12 %   11 %

Pravachol

     234      195      429      119      548      96      644      78      85      163      69      232          -42 %   -58 %

Avapro/Avalide

     94      113      207      118      325      125      450      107      127      234      133      367          13 %   13 %

Coumadin

     8      9      17      8      25      9      34      8      9      17      10      27          25 %   8 %

Virology

     209      254      463      240      703      253      956      271      285      556      319      875          33 %   24 %

Reyataz

     88      114      202      104      306      111      417      120      116      236      132      368          27 %   20 %

Sustiva Franchise****

     67      78      145      73      218      78      296      82      86      168      86      254          18 %   17 %

Baraclude

     2      5      7      8      15      18      33      28      39      67      50      117          *     *  

Oncology

     202      214      416      198      614      199      813      173      173      346      194      540          -2 %   -12 %

Erbitux

     2      —        2      2      4      2      6      2      2      4      2      6          —       50 %

Taxol

     143      145      288      135      423      128      551      107      91      198      101      299          -25 %   -29 %

Sprycel

     —        —        —        —        —        3      3      11      21      32      29      61          —       —    

Affective (Psychiatric) Disorders

     86      90      176      88      264      102      366      103      125      228      121      349          38 %   32 %

Abilify**

     52      57      109      53      162      68      230      73      90      163      91      254          72 %   57 %

Immunoscience

     —        —        —        —        —        1      1      1      2      3      3      6          —       —    

Orencia

     —        —        —        —        —        1      1      1      2      3      3      6          —       —    

Other Pharmaceuticals

                                              

Efferalgan

     68      62      130      62      192      74      266      81      69      150      71      221          15 %   15 %

HEALTH CARE GROUP

     498      504      1,002      518      1,520      538      2,058      531      566      1,097      595      1,692          15 %   11 %

NUTRITIONALS

     318      300      618      315      933      323      1,256      332      345      677      371      1,048          18 %   12 %

Enfamil

     82      79      161      77      238      81      319      83      90      173      86      259          12 %   9 %

Enfagrow

     67      59      126      69      195      67      262      72      70      142      74      216          7 %   11 %

OTHER HEALTH CARE

     180      204      384      203      587      215      802      199      221      420      224      644          10 %   10 %

CONVATEC

     157      177      334      181      515      190      705      176      193      369      198      567          9 %   10 %

Ostomy

     89      100      189      100      289      106      395      96      109      205      105      310          5 %   7 %

Wound Therapeutics

     68      73      141      77      218      80      298      75      83      158      88      246          14 %   13 %

MEDICAL IMAGING

     23      27      50      22      72      25      97      23      28      51      26      77          18 %   7 %

Cardiolite

     12      14      26      11      37      13      50      12      14      26      11      37          —       —    

* This table presents Total Company sales on a legal entity source basis and segment and product sales on a country management reported basis. As a result, the sum of segment sales does not tie to Total Company sales.
** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** In excess of +/- 200%
**** Beginning in the third quarter of 2006, Sustiva Franchise includes sales of Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc.

 

6


BRISTOL-MYERS SQUIBB COMPANY

U.S. PHARMACEUTICALS AND PLAVIX NET SALES

EXCLUDING ESTIMATED IMPACT OF LAUNCH OF GENERIC CLOPIDOGREL BISULFATE

($ in millions)

 

    

2007

Q3

  

2006

Q3

  

% Change

Qtr vs. Qtr

 

U.S Pharmaceuticals Net Sales

        

U.S Pharmaceuticals Net Sales as Reported

   $ 2,295      $1,609    43 %

Estimated Impact of Launch of Generic Clopidogrel Bisulfate

     —        525 to 600    —    
                    

U.S Pharmaceuticals Net Sales Excluding the Estimated Impact of Launch of Generic Clopidogrel Bisulfate

   $ 2,295    $ 2,134 to $2,209    4% to 8 %
                    
    

2007

Q3

  

2006

Q3

  

% Change

Qtr vs. Qtr

 

U.S Plavix Net Sales

        

U.S Plavix Net Sales as Reported

   $ 1,080      $474    128 %

Estimated Impact of Launch of Generic Clopidogrel Bisulfate

     —        525 to 600    —    
                    

U.S Plavix Net Sales Excluding the Estimated Impact of Launch of Generic Clopidogrel Bisulfate

   $ 1,080    $ 999 to $1,074    1% to 8 %
                    

 

7


BRISTOL-MYERS SQUIBB COMPANY

GROSS MARGIN

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2007  
     Q1     Q2     Q3           TOTAL YEAR  
Net Sales    $ 4,476     $ 4,928     $ 5,050       $ 14,454  
                                  

Gross Profit

          

Gross Profit

   $ 3,084     $ 3,379     $ 3,428       $ 9,891  

Specified items*

     16       13       17         46  
                                  

Gross Profit Excluding Specified Items

   $ 3,100     $ 3,392     $ 3,445       $ 9,937  
                                  

Gross Margin %

          

Gross Margin %

     68.9 %     68.6 %     67.9 %       68.4 %

Specified items*

     0.4 %     0.2 %     0.3 %       0.3 %
                                  

Gross Margin % Excluding Specified Items

     69.3 %     68.8 %     68.2 %       68.7 %
                                  
     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR  
Net Sales    $ 4,676     $ 4,871     $ 4,154     $ 4,213     $ 17,914  
                                        

Gross Profit

          

Gross Profit

   $ 3,200     $ 3,303     $ 2,689     $ 2,766     $ 11,958  

Specified items*

     46       20       72       29       167  
                                        

Gross Profit Excluding Specified Items

   $ 3,246     $ 3,323     $ 2,761     $ 2,795     $ 12,125  
                                        

Gross Margin %

          

Gross Margin %

     68.4 %     67.8 %     64.7 %     65.7 %     66.8 %

Specified items*

     1.0 %     0.4 %     1.8 %     0.6 %     0.9 %
                                        

Gross Margin % Excluding Specified Items

     69.4 %     68.2 %     66.5 %     66.3 %     67.7 %
                                        

* Please refer to the Specified Item - QTD tab for detail of specified items.

 

8


BRISTOL-MYERS SQUIBB COMPANY

RESEARCH AND DEVELOPMENT EXPENSES

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2007
     Q1    Q2    Q3         TOTAL
YEAR

Research and Development Expenses

   $ 807    $ 778    $ 827       $ 2,412

Specified items*

     80      17      60         157
                              

Research and Development Expenses Excluding Specified Items

   $ 727    $ 761    $ 767       $ 2,255
                              
     2006
     Q1    Q2    Q3    Q4    TOTAL
YEAR

Research and Development Expenses

   $ 750    $ 740    $ 756    $ 821    $ 3,067

Specified items*

     18      1      17      49      85
                                  

Research and Development Expenses Excluding Specified Items

   $ 732    $ 739    $ 739    $ 772    $ 2,982
                                  

* Please refer to the Specified Item—QTD tab for detail of specified items.

 

9


BRISTOL-MYERS SQUIBB COMPANY

EFFECTIVE TAX RATE

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2007  
     Q1     Q2     Q3           TOTAL
YEAR
 

Provision for Income Taxes

          

Provision for Income Taxes

   $ 86     $ 257     $ 342       $ 685  

Specified items*

     79       5       (82 )       2  
                                  

Provision for Income Taxes Excluding Specified Items

   $ 165     $ 262     $ 260       $ 687  
                                  

Earnings Before Minority Interest and Provision for Income Taxes

   $ 917     $ 1,157     $ 1,411       $ 3,485  

Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,050     $ 1,182     $ 1,235       $ 3,467  

Effective Tax Rate

          

Effective Tax Rate

     9.4 %     22.2 %     24.2 %       19.7 %

Effective Tax Rate Excluding Specified Items

     15.7 %     22.2 %     21.1 %       19.8 %
     2006  
     Q1     Q2     Q3     Q4     TOTAL
YEAR
 

Provision for Income Taxes

          

Provision/(Benefit) for Income Taxes

   $ 328     $ 256     $ 193     $ (167 )   $ 610  

Specified items*

     (49 )     (3 )     (34 )     196       110  
                                        

Provision for Income Taxes Excluding Specified Items

   $ 279     $ 253     $ 159     $ 29     $ 720  
                                        

Earnings/(Loss) Before Minority Interest and Provision for Income Taxes

   $ 1,193     $ 1,110     $ 617     $ (285 )   $ 2,635  

Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,081     $ 1,120     $ 670     $ 425     $ 3,296  

Effective Tax Rate

          

Effective Tax Rate

     27.5 %     23.1 %     31.3 %     58.6 %     23.1 %

Effective Tax Rate Excluding Specified Items

     25.8 %     22.6 %     23.7 %     6.8 %     21.8 %

* Please refer to the Specified Item—QTD tab for detail of specified items.

 

10


BRISTOL-MYERS SQUIBB COMPANY

EARNINGS BEFORE MINORITY INTEREST AND INCOME TAXES

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2007  
     Q1     Q2     Q3           TOTAL YEAR  

Earnings Before Minority Interest and Provision for Income Taxes

   $ 917     $ 1,157     $ 1,411       $ 3,485  

Specified items:

          

Upfront and milestone payments

     80       17       60         157  

Downsizing and streamlining of worldwide operations

     53       20       17         90  

Litigation matters

     —         14       5         19  

Insurance recoveries

     —         —         (11 )       (11 )

Gain on sale of product assets

     —         (26 )     (247 )       (273 )
                                  

Subtotal

     133       25       (176 )       (18 )
                                  

Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,050     $ 1,182     $ 1,235       $ 3,467  
                                  
     2006  
     Q1     Q2     Q3     Q4    

TOTAL YEAR

 

Earnings / (Loss) Before Minority Interest and Provision for Income Taxes

   $ 1,193     $ 1,110     $ 617     ($ 285 )   $ 2,635  

Specified items:

          

Gain on sale of product asset

     (200 )     —         —         —         (200 )

Litigation matters

     40       (14 )     (29 )     353       350  

Insurance recoveries

     (21 )     —         (9 )     (7 )     (37 )

Downsizing and streamlining of worldwide operations

     69       24       91       131       315  

Debt retirement costs

     —         —         —         220       220  

Claim for damages

     —         —         —         13       13  
                                        

Subtotal

     (112 )     10       53       710       661  
                                        

Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,081     $ 1,120     $ 670     $ 425     $ 3,296  
                                        

 

11


BRISTOL-MYERS SQUIBB COMPANY

DILUTED EARNINGS PER COMMON SHARE

EXCLUDING SPECIFIED ITEMS

 

     2007  
     Q1     Q2     Q3           TOTAL YEAR *  

Diluted Earnings per Common Share

   $ 0.35     $ 0.36     $ 0.43       $ 1.14  

Specified items:

          

Upfront and milestone payments

     0.03       0.01       0.01         0.05  

Downsizing and streamlining of worldwide operations

     0.02       0.01       0.01         0.04  

Gain on sale of product assets

     —         (0.01 )     (0.07 )       (0.08 )

Tax item

     (0.02 )     —         —           (0.02 )
                                  

Subtotal

     0.03       0.01       (0.05 )       (0.01 )
                                  

Diluted Earnings per Common Share Excluding Specified Items

   $ 0.38     $ 0.37     $ 0.38       $ 1.13  
                                  
     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR *  

Diluted Earnings / (Loss) per Common Share

   $ 0.36     $ 0.34     $ 0.17     $ (0.07 )   $ 0.81  

Specified items:

          

Gain on sale of product asset

     (0.06 )     —         —         —         (0.06 )

Litigation matters

     0.01       —         (0.01 )     0.14       0.14  

Insurance recoveries

     (0.01 )     —         —         —         (0.01 )

Downsizing and streamlining of worldwide operations / other

     0.02       0.01       0.04       0.05       0.12  

Debt retirement costs

     —         —         —         0.07       0.07  

Tax item

     —         —         0.02       —         0.02  
                                        

Subtotal

     (0.04 )     0.01       0.05       0.26       0.28  
                                        

Diluted Earnings per Common Share Excluding Specified Items

   $ 0.32     $ 0.35     $ 0.22     $ 0.19     $ 1.09  
                                        

* quarterly amounts may not add to the annual total due to rounding of individual calculations.

 

12


BRISTOL-MYERS SQUIBB COMPANY

SPECIFIED ITEMS

FOR THE THREE MONTHS ENDED SEPTEMBER 30, 2007 AND 2006

($ in millions)

Three months ended September 30, 2007

 

     Cost of
products
sold
   Research and
development
   Gain on sale of
product assets
    Other
(income)/expense,
net
    Total  

Litigation Matters:

            

Insurance recovery

   $ —      $ —      $ —       $ (11 )   $ (11 )

Product liability

     —        —        —         5       5  
                                      
     —        —        —         (6 )     (6 )

Other:

            

Upfront and milestone payments

     —        60      —         —         60  

Accelerated depreciation and asset impairment

     17      —        —         —         17  

Gain on sale of product assets

     —        —        (247 )     —         (247 )
                                      
   $ 17    $ 60    $ (247 )   $ (6 )     (176 )
                                

Income taxes on items above

               82  
                  

(Increase)/Decrease to Net Earnings

             $ (94 )
                  

Three months ended September 30, 2006

 

     Cost of
products
sold
   Research and
development
   Provision for
restructuring, net
   Litigation
income, net
    Other
(income)/
expense, net
    Total  

Litigation Matters:

               

Insurance recovery

   $ —      $ —      $ —      $ (9 )   $ —       $ (9 )

Product liability

     —        —        —        —         11       11  

Commercial litigation

     —        —        —        —         (40 )     (40 )
                                             
     —        —        —        (9 )     (29 )     (38 )

Other:

               

Accelerated depreciation and asset impairment

     72      —        —        —         —         72  

Downsizing and streamlining of worldwide operations

     —        —        2      —         —         2  

Upfront and milestone payments

     —        17      —        —         —         17  
                                             
   $ 72    $ 17    $ 2    $ (9 )   $ (29 )     53  
                                       

Income taxes on items above

                  (5 )

Minority interest, net of taxes

                  13  

Change in estimate for taxes on prior year items

                  39  
                     

(Increase)/Decrease to Net Earnings

                $ 100  
                     

 

13


BRISTOL-MYERS SQUIBB COMPANY

SPECIFIED ITEMS

FOR THE NINE MONTHS ENDED SEPTEMBER 30, 2007 AND 2006

($ in millions)

Nine months ended September 30, 2007

 

    

Cost of
products

sold

   Research and
development
  

Provision for
restructuring,

net

  

Litigation
expense,

net

   Other (income)/
expense, net
   

Gain on

sale of

product
assets

    Total  

Litigation Matters:

                  

Litigation settlement

   $ —      $ —      $ —      $ 14    $ —       $ —       $ 14  

Insurance recovery

     —        —        —        —        (11 )     —         (11 )

Product liability

     —        —        —        —        5       —         5  
                                                    
     —        —        —        14      (6 )     —         8  

Other:

                  

Upfront and milestone payments

     —        157      —        —        —         —         157  

Accelerated depreciation and asset impairment

     46      —        —        —        —         —         46  

Downsizing and streamlining of worldwide operations

     —        —        44      —        —         —         44  

Gain on sale of product assets

     —        —        —        —        —         (273 )     (273 )
                                                    
   $ 46    $ 157    $ 44    $ 14    $ (6 )   $ (273 )     (18 )
                                              

Income taxes on items above

                     37  

Change in estimate for taxes on a prior year specified item

                     (39 )
                        

(Increase)/Decrease to Net Earnings

                   $ (20 )
                        

Nine months ended September 30, 2006

 

    

Cost of
products

sold

   Research and
development
   Marketing
selling and
administrative
   Provision for
restructuring,
net
   Litigation
income,
net
    Other
(income)/
expense,
net
   Gain on
sale of
product
asset
    Total  

Litigation Matters:

                     

Insurance recovery

   $ —      $ —      $ —      $ —      $ (30 )   $ —      $ —       $ (30 )

Product liability

     —        —        —        —        —         11      —         11  

Commercial litigations

     —        —        —        —        (14 )     —        —         (14 )
                                                           
     —        —        —        —        (44 )     11      —         (33 )

Other:

                     

Accelerated depreciation, asset impairment and contract termination

     138      1      4      —        —         —        —         143  

Downsizing and streamlining of worldwide operations

     —        —        —        6      —         —        —         6  

Upfront and milestone payments

     —        35      —        —        —         —        —         35  

Gain on sale of product asset

     —        —        —        —        —         —        (200 )     (200 )
                                                           
   $ 138    $ 36    $ 4    $ 6    $ (44 )   $ 11    $ (200 )     (49 )
                                                     

Income taxes on items above

                        47  

Change in estimate for taxes on prior year items

                        39  
                           

(Increase)/Decrease to Net Earnings

                      $ 37  
                           

 

14


BRISTOL-MYERS SQUIBB COMPANY

SELECT BALANCE SHEET INFORMATION

($ in millions)

 

     March 31,    June 30,    September 30,    December 31,     March 31,    June 30,    September 30,    December 31,
     2006    2006    2006    2006     2007    2007    2007    2007

Cash, cash equivalents and marketable
debt securities

   $ 5,281    $ 5,357    $ 5,505    $ 4,013     $ 4,012    $ 4,646    $ 3,582   

Short-term borrowings

     234      189      630      187       241      256      1,879   

Long-term debt

     8,278      8,239      7,837      7,248       7,132      6,978      4,248   
                                                    

Net debt

   $ 3,231    $ 3,071    $ 2,962    $ 3,422     $ 3,361    $ 2,588    $ 2,545   
                                                    

Receivables, net of allowances

   $ 3,236    $ 3,326    $ 2,945    $ 3,247     $ 3,381    $ 3,632    $ 3,704   

Stockholders' equity

     11,556      11,712      11,589      9,991 (1)     10,261      10,762      11,153   

Capital expenditures and capitalized
software (for the quarter ended)

     202      160      199      224       202      206      185   

(1) Includes the impact of the adoption of SFAS 158, "Employers' Accounting for Defined Benefit Pension and Other Postretirement Plans - an amendment of FASB Statements No. 87, 88, 106 and 132(R)"

 

15


BRISTOL-MYERS SQUIBB COMPANY

2007 FULL YEAR PROJECTED DILUTED EPS

EXCLUDING PROJECTED SPECIFIED ITEMS

 

     Full Year 2007  

Projected Diluted Earnings per Common Share

   $ 1.28 to $1.33  

Projected Specified Items:

  

In-process R&D charge

     0.12  

Upfront and milestone payments

     0.06  

Downsizing and streamlining of worldwide operations

     0.06  

Gain on sale of product assets

     (0.08 )

Tax item

     (0.02 )
        

Total

     0.14  
        

Projected Diluted Earnings per Common Share Excluding Specified Items

   $ 1.42 to $1.47  
        

2007 and 2008 Gross Margin/Research and Development/Tax Rate Projections Excluding Specified Items

Gross margin on a GAAP basis for the nine months ended September 30, 2007 was 68.4%, which included specified items of $46 million and had a 0.3% adverse impact on gross margin in aggregate. On a non-GAAP basis, for the nine months ended September 30, 2007 gross margin was 68.7%. On a non-GAAP basis, based on historical trends in 2006 and for the nine months ended September 30, 2007 the Company projects gross margin for the full year 2007 to be at least 100 basis points higher than 2006 and for the full year 2008 to improve slightly compared to the full year 2007 estimate. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on gross margin. See Gross Margin non comparable tab.

Research and development expenses on a GAAP basis for the nine months ended September 30, 2007 were $2,412 million, which included specified items of $157 million. On a non-GAAP basis, for the nine months ended September 30, 2007 research and development expenses were $2,255 million. On a non-GAAP basis, based on historical trends in 2006 and for the nine months ended September 30, 2007 the Company projects research and development expenses for the full year 2007 to increase in the mid single digit range compared to 2006 and for the full year 2008 to increase in the mid single digit range compared to the full year 2007 estimate. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on research and development. See R&D non comparable tab.

The effective tax rate on a GAAP basis for the nine months ended September 30, 2007 was 19.7%, which included specified items of $2 million in the tax provision, and had a 0.1% favorable impact on the effective tax rate in aggregate. On a non-GAAP basis, for the nine months ended September 30, 2007 effective tax rate was 19.8%. On a non-GAAP basis, based on historical trends in 2006 and for the nine months ended September 30, 2007 the Company projects effective tax rate for the full year 2007 to be in the 20% range and for the full year 2008 to be in the 22% to 24% range. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on the tax rate. See Tax Rate non comparable tab.

The GAAP results for the full year 2007 and 2008 would include specified items that may occur and impact results, including restructuring and other charges that cannot be reasonably estimated at this time in connection with the Company's comprehensive cost reduction programs, including charges relating to workforce reductions and the rationalization of some facilities. While the amount and timing of these restructuring and other charges cannot be reasonably estimated at this time, the Company expects that the charges are likely to be incurred over the next three years and are reasonably likely to be material. These specified items could also include charges and recoveries relating to significant legal proceedings, debt retirement costs and other charges related to new transactions, upfront and milestone payments, copromotion or alliance charges and charges for in-process research and development related to new external development transactions, gains or losses from asset disposals, restructuring activities and significant tax events. For a fuller discussion of certain of the litigation and other matters that could impact full year GAAP results, as well as the use of non-GAAP financial information, see Bristol-Myers Squibb Company Reports Financial Results For The Third Quarter of 2007, October 25, 2007, including “Outlook for 2007 and 2008” and “Use of Non-GAAP Financial Information” therein.

 

16


BRISTOL-MYERS SQUIBB COMPANY

ESTIMATED MONTHS ON HAND OF TOP 15 U.S. PHARMACEUTICAL PRODUCTS

IN THE U.S. WHOLESALER DISTRIBUTION CHANNEL

The following tables sets forth, for each of the Company’s top 15 pharmaceutical products (based on 2006 annual net sales) sold by the Company's U.S. Pharmaceuticals business, the U.S. Pharmaceuticals net sales and the estimated number of months on hand of the applicable product in the U.S. wholesaler distribution channel for the quarters ended September 30, 2007 and 2006 and June 30, 2007 and 2006.

 

     September 30, 2007    September 30, 2006    June 30, 2007    June 30, 2006
     Net Sales     Months
on
Hand
   Net Sales    Months
on
Hand
   Net Sales    Months
on
Hand
   Net Sales    Months
on
Hand
     (Dollars in Millions)         

(Dollars in Millions)

       

(Dollars in Millions)

       

(Dollars in Millions)

    

Abilify (total revenue)

   $ 329     0.4    $ 260    0.5    $ 322    0.4    $ 267    0.5

Avapro/Avalide

     176     0.4      159    0.4      170    0.4      167    0.5

Baraclude

     22     0.5      14    0.6      20    0.7      9    0.7

Coumadin

     40     0.6      45    0.7      43    0.7      46    0.8

Erbitux (a)

     183     0.3      173    0.5      160    0.4      172    —  

Glucophage Franchise

     17     0.6      20    0.7      17    0.6      22    0.6

Kenalog

     20     0.6      19    0.8      26    0.5      22    0.8

Orencia (b)

     57     0.4      34    0.8      53    0.5      18    0.3

Paraplatin

     (1 )   25.0      5    1.5      1    17.5      2    1.7

Plavix

     1,080     0.4      474    1.5      1,015    0.4      988    0.5

Pravachol

     17     0.7      73    1.0      47    0.5      128    1.0

Reyataz

     141     0.5      129    0.5      138    0.6      122    0.6

Sprycel

     17     0.7      11    1.2      14    0.8      —      —  

Sustiva Franchise (c) (total revenue)

     151     0.6      128    0.5      147    0.7      115    0.5

Zerit

     13     0.7      19    0.7      15    0.7      18    0.7

For all products other than Erbitux and Orencia, the Company determines the above months on hand estimates by dividing the estimated amount of the product in the U.S. wholesaler distribution channel by the estimated amount of out-movement of the product from the U.S. wholesaler distribution channel over a period of 31 days, all calculated as described below. Factors that may influence the Company's estimates include generic competition, seasonality of products, wholesaler purchases in light of increases in wholesaler list prices, new product launches, new warehouse openings by wholesalers and new customer stockings by wholesalers. In addition, such estimates are calculated using third-party data, which represent their own record-keeping processes and as such, may also reflect estimates.

Estimates of product in the wholesaler distribution channel and out-movement are based on weekly information received directly from third-parties, and excludes any inventory held by intermediaries such as retailers and hospitals, and excludes goods in transit to such wholesalers. The Company determines the amount of out-movement of a product over a period of 31 days by using the most recent out-movement of a product as provided by these third parties, adjusted to reflect the Company's estimate of goods in transit to these wholesalers. The Company estimates the amount of goods in transit by using information provided by these wholesalers with respect to their open orders and the Company's records of sales to these wholesalers with respect to such open orders.

 

(a) The Company sells Erbitux to intermediaries (such as wholesalers and specialty oncology distributors) and ships Erbitux directly to the end-users of the product who are the customers of those intermediaries. The Company also sells Erbitux to other distributors who then hold Erbitux inventory. The above estimate of months on hand was calculated by dividing the inventories of Erbitux held by the distributors for their own accounts as reported by the distributors as of the end of the quarter by the out-movements of the product reported by the distributors over the last 31 day period. The inventory levels reported by the distributors are a product of their record-keeping process.

 

(b) The Company distributes Orencia through distribution arrangements with multiple distributors. The above estimates of months on hand was calculated by dividing the inventories of Orencia held by these distributors at the end of the quarter by the out-movement of the product over the last 31 day period, as reported by these distributors. The inventory on hand and out-movements reported by these distributors are a product of the distributors’ own record-keeping processes.

 

(c) Beginning in the third quarter of 2006, Sustiva Franchise includes sales of Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. The estimated months on hand of the product in the U.S. wholesale distribution channel only include branded Sustiva inventory.

 

17


BRISTOL-MYERS SQUIBB COMPANY

ESTIMATED MONTHS ON HAND OF TOP INTERNATIONAL PHARMACEUTICAL

AND WORLDWIDE NON-PHARMACEUTICAL PRODUCTS

The following table, which was posted on the Company's website and filed on Form 8-K on August 31, 2007, sets forth for each of the Company’s key products sold by the businesses listed below, the net sales of the applicable product for each of the quarters ended June 30, 2007, March 31, 2007, June 30, 2006 and March 31, 2006, and the estimated number of months on hand of the applicable product in the direct customer distribution channel for the business as of the end of each of the four quarters. The estimates of months on hand for key products described below for the International Pharmaceuticals business are based on data collected for all of the Company’s significant business units outside of the U.S. For the other non-Pharmaceuticals reporting segments, estimates are based on data collected for the U.S. and all significant business units outside of the U.S.

 

     June 30, 2007    March 31, 2007    June 30, 2006    March 31, 2006
     Net Sales    Months
on
Hand
   Net Sales    Months
on
Hand
   Net Sales    Months
on
Hand
   Net Sales    Months
on
Hand
     (Dollars in Millions)         (Dollars in Millions)         (Dollars in Millions)         (Dollars in Millions)     

International Pharmaceuticals

                       

Abilify (total revenue)

   $ 90    0.6    $ 73    0.6    $ 57    0.6    $ 52    0.6

Avapro/Avalide

     127    0.5      107    0.5      113    0.5      94    0.5

Baraclude

     39    0.7      28    0.7      5    1.0      2    1.1

Bufferin

     27    0.5      24    0.5      31    0.5      22    0.6

Capoten

     25    0.9      26    0.8      31    0.9      35    0.8

Dafalgan

     42    1.4      44    1.2      37    1.1      37    1.4

Efferalgan

     69    1.4      81    1.1      62    0.9      68    1.2

Maxipime

     39    0.8      29    0.5      43    0.8      40    0.8

Monopril

     42    1.2      36    0.8      48    1.1      46    1.1

Orencia

     2    0.4      1    0.3      —      —        —      —  

Perfalgan

     65    0.5      58    0.5      51    0.6      46    0.6

Plavix

     174    0.6      151    0.5      157    0.5      136    0.5

Pravachol

     85    0.6      78    0.6      195    1.4      234    1.5

Reyataz

     116    0.7      120    0.9      114    0.7      88    0.6

Sprycel

     21    0.4      11    0.4      —      —        —      —  

Sustiva Franchise (a)

     86    0.5      82    0.5      78    0.5      67    0.5

Taxol

     91    0.6      107    0.7      145    0.5      143    0.6

Videx/Videx EC

     27    1.1      27    1.1      35    1.2      31    0.8

Nutritionals

                       

Enfamil/Enfagrow

     337    0.9      326    0.8      312    0.9      304    0.9

Nutramigen

     54    1.0      52    0.9      54    1.0      48    1.0

Other Health Care

                       
ConvaTec                        

Ostomy

     150    0.9      130    0.9      141    1.0      123    0.9

Wound Therapeutics

     119    0.9      107    0.9      107    0.9      98    0.9
Medical Imaging                        

Cardiolite

     106    0.7      99    0.7      105    0.8      103    0.8

(a) Beginning in the third quarter of 2006, Sustiva Franchise includes sales of Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. The estimated months on hand of the product in the distribution channel only include branded Sustiva inventory.

The above months on hand information represents the Company’s estimates of aggregate product level inventory on hand at direct customers divided by the expected demand for the applicable product. Expected demand is the estimated ultimate patient/consumer demand calculated based on estimated end-user consumption or direct customer out-movement data over the most recent 31 day period or other reasonable period. Factors that may affect the Company’s estimates include generic competition, seasonality of products, direct customer purchases in light of price increases, new product or product presentation launches, new warehouse openings by direct customers, new customer stockings by direct customers and expected direct customer purchases for governmental bidding situations.

 

18


Estimated End-User Demand

U.S. Pharmaceuticals

The following tables set forth for each of the Company’s top 15 pharmaceutical products (based on 2006 annual net sales) sold by the U.S. Pharmaceuticals business, for the three months ended September 30, 2007 compared to the same periods in the prior year: (i) changes in reported U.S. net sales for the period; (ii) estimated total U.S. prescription change for the retail and mail order channels calculated by the Company based on NGPS version 2.0 data on a weighted average basis; and (iii) the estimated U.S. therapeutic category share of the applicable product calculated by the Company based on NGPS version 2.0 data on a weighted-average basis. Prior year prescription data has been adjusted to conform to the NGPS version 2.0 data.

 

     Three Months Ended September 30, 2007     Month Ended September 30, 2007  
     Change in U.S.
Net Sales(a)
    Change in U.S.
Total Prescriptions(b)
    Estimated TRx
Therapeutic
Category Share (b, c)
 

ABILIFY* (total revenue)

   27 %   10 %   13 %

AVAPRO*/AVALIDE*

   11     (4 )   13  

BARACLUDE

   57     71     29  

COUMADIN

   (11 )   (15 )   14  

ERBITUX* (d)

   6     N/A     N/A  

GLUCOPHAGE* Franchise

   (15 )   (30 )   1  

KENALOG (e)

   5     N/A     N/A  

ORENCIA(d)

   68     N/A     N/A  

PARAPLATIN (d)

   (120 )   N/A     N/A  

PLAVIX*

   128     86     87  

PRAVACHOL

   (77 )   (77 )   —    

REYATAZ (f)

   9     10     19  

SPRYCEL (g)

   55     * *   6  

SUSTIVA Franchise (f, h) (total revenue)

   18     19     36  

ZERIT

   (32 )   (29 )   4  

 

     Three Months Ended September 30, 2006     Month Ended September 30, 2006  
     Change in U.S.
Net Sales(a)
    Change in U.S.
Total Prescriptions(b)
    Estimated TRx
Therapeutic
Category Share(b, c)
 
                  

ABILIFY* (total revenue)

   21 %   18 %   12 %

AVAPRO*/AVALIDE*

   8     1     14  

BARACLUDE

   * *   * *   21  

COUMADIN

   (8 )   (18 )   16  

ERBITUX* (d)

   63     N/A     N/A  

GLUCOPHAGE* Franchise

   (47 )   (52 )   1  

KENALOG (e)

   —       N/A     N/A  

ORENCIA (d)

   —       N/A     N/A  

PARAPLATIN (d)

   (44 )   N/A     N/A  

PLAVIX*

   (43 )   (36 )   19  

PRAVACHOL

   (75 )   (82 )   1  

REYATAZ (f)

   23     14     18  

SPRYCEL (g)

   —       —       3  

SUSTIVA (f)

   27     11     32  

ZERIT

   (21 )   (32 )   5  

(a) Reflects percentage change in net sales in dollar terms, including change in average selling prices and wholesaler buying patterns.

 

19


(b) Derived by multiplying NGPS mail order prescription data by a factor that approximates three and adding to this the NGPS retail prescriptions.

 

(c) The therapeutic categories are determined by the Company as those products considered to be in direct competition with the Company’s own products. The products listed above compete in the following therapeutic categories: ABILIFY* (antipsychotics), AVAPRO*/AVALIDE* (angiotensin receptor blockers), BARACLUDE (oral antiviral agent), COUMADIN (warfarin), ERBITUX* (oncology), GLUCOPHAGE* Franchise (oral antidiabetics), KENALOG (intra-articular/intramuscular steroid), ORENCIA (fusion protein), PARAPLATIN (carboplatin), PLAVIX* (antiplatelet agents), PRAVACHOL (HMG CoA reductase inhibitors), REYATAZ and the SUSTIVA Franchise (antiretrovirals - third agents excluding NORVIR* and TRIZIVIR*), SPRYCEL (TKIs for leukemia), and ZERIT (nucleoside reverse transcriptase inhibitors).

 

(d) ERBITUX*, ORENCIA and PARAPLATIN are parenterally administered products and do not have prescription-level data as physicians do not write prescriptions for these products. The Company believes therapeutic category share information provided by third parties for these products may not be reliable and accordingly, none is presented here.

 

(e) The Company does not have prescription level data because the product is not dispensed through a retail pharmacy. The Company believes therapeutic category share information provided by third parties for this product may not be reliable and accordingly, none is presented here.

 

(f) REYATAZ and the SUSTIVA Franchise have been recalculated as a percentage share of antiretrovirals – third agents excluding NORVIR* and TRIZIVIR*.

 

(g) SPRYCEL was launched in the U.S. in July 2006.

 

(h) SUSTIVA Franchise (total revenue) includes sales of SUSTIVA, as well as revenue of bulk efavirenz included in the combination therapy, ATRIPLA*. The therapeutic category share information and change in U.S. total prescriptions growth for SUSTIVA Franchise (antiretrovirals – third agents excluding NORVIR* and TRIZIVIR*) includes both branded SUSTIVA and ATRIPLA* prescription units.

 

** In excess of 200%.

The Company is reporting REYATAZ’s estimated TRx category share within the antiretrovirals—third agents (excluding NORVIR* and TRIZIVIR*) category rather than the protease inhibitors (excluding NORVIR*) category. The Company believes that the antiretrovirals - third agents (excluding NORVIR* and TRIZIVIR*) category more closely reflects the use of protease inhibitors, which has evolved and competes with other products within the antiretrovirals—third agents (excluding NORVIR* and TRIZIVIR*) category. The historical trends of growth in REYATAZ’s estimated TRx category share between the two categories are not materially different.

As previously reported, in July 2007, IMS issued a Product News bulletin announcing that it had revised its previously issued projected prescription and unit volumes for PLAVIX* and Apotex’s generic clopidogrel bisulfate product, which IMS had overstated for the months August 2006 through June 2007 due to market events surrounding the at-risk launch of generic clopidogrel bisulfate. Due to these unique circumstances, the high degree of volatility and the compressed timeframe of these events, IMS applied a custom approach to estimate PLAVIX* and generic clopidogrel bisulfate product and market volumes beginning in July 2007.

In October 2007, IMS issued a further Product News bulletin, announcing the discontinuation of the custom approach to estimate PLAVIX* and generic clopidogrel bisulfate product and market volumes in favor of its standard approach beginning October 2007.

The IMS overstatement of PLAVIX* prescription and unit volumes did not impact the Company’s financial results or its reported net sales for PLAVIX* for the quarters ended September 30, 2006, December 31, 2006, March 31, 2007 and June 30, 2007.

 

20


The following table sets forth the Company’s (i) previously reported estimated prescription change data and estimated therapeutic category share based on National Prescription Audit (NPA) data for the quarters ended September 30, 2006 and December 31, 2006; (ii) previously reported estimated prescription change data and estimated therapeutic category share based on NGPS version 2.0 data for the quarter ended March 31, 2007; and (iii) revised estimated prescription change data and estimated therapeutic category share based on revised NGPS version 2.0 data using the IMS custom approach.

 

     PLAVIX*    

Clopidogrel Bisulfate

(Branded and Generic)

 
    

As Reported

(NPA Data)

   

Revised

(NGPS v2
Data)

   

As Reported

(NPA Data)

   

Revised

(NGPS v2
Data)

 

Change in U.S. Total Prescriptions

        

Three Months Ended March 31, 2007(a)

   (28 )%   (36 )%   18 %   9 %

Three Months Ended December 31, 2006

   (64 )   (70 )   14     11  

Three Months Ended September 30, 2006

   (32 )   (36 )   14     11  

Twelve Months Ended December 31, 2006

   (18 )   (21 )   14     12  

Nine Months Ended September 30, 2006

   (2 )   (4 )   N/A     N/A  

Estimated TRx Therapeutic Category Share

        

Month Ended March 31, 2007(a)

   65     62     N/A     N/A  

Month Ended December 31, 2006

   34     29     N/A     N/A  

Month Ended September 30, 2006

   23     19     N/A     N/A  

 

(a) NGPS version 2.0 data

The estimated prescription change data and estimated therapeutic category share reported throughout this Form 10-Q only include information from the retail and mail order channels and do not reflect information from other channels, such as hospitals, institutions and long-term care, among others. The data provided by IMS are a product of IMS’ own record-keeping processes and are estimates based on IMS’ sampling procedures, subject to the inherent limitations of estimates based on sampling and a margin of error.

 

21


Estimated Inventory Months on Hand in the Distribution Channel

U.S. Pharmaceuticals

The following tables set forth for each of the Company’s top 15 pharmaceutical products (based on 2006 annual net sales) sold by the Company’s U.S. Pharmaceuticals business, the U.S. Pharmaceuticals net sales and the estimated number of months on hand of the applicable product in the U.S. wholesaler distribution channel for the quarters ended September 30, 2007 and 2006 and June 30, 2007 and 2006.

 

     September 30, 2007    September 30, 2006

Dollars in Millions

   Net Sales     Months
on Hand
   Net Sales    Months
on Hand

ABILIFY* (total revenue)

   $ 329     0.4    $ 260    0.5

AVAPRO*/AVALIDE*

     176     0.4      159    0.4

BARACLUDE

     22     0.5      14    0.6

COUMADIN

     40     0.6      45    0.7

ERBITUX*

     183     0.3      173    0.5

GLUCOPHAGE* Franchise

     17     0.6      20    0.7

KENALOG

     20     0.6      19    0.8

ORENCIA

     57     0.4      34    0.8

PARAPLATIN

     (1 )   25.0      5    1.5

PLAVIX*

     1,080     0.4      474    1.5

PRAVACHOL

     17     0.7      73    1.0

REYATAZ

     141     0.5      129    0.5

SPRYCEL

     17     0.7      11    1.2

SUSTIVA Franchise (a) (total revenue)

     151     0.6      128    0.5

ZERIT

     13     0.7      19    0.7

 

     June 30, 2007    June 30, 2006

Dollars in Millions

   Net Sales    Months
on Hand
   Net Sales    Months
on Hand

ABILIFY* (total revenue)

   $ 322    0.4    $ 267    0.5

AVAPRO*/AVALIDE*

     170    0.4      167    0.5

BARACLUDE

     20    0.7      9    0.7

COUMADIN

     43    0.7      46    0.8

ERBITUX*

     160    0.4      172    —  

GLUCOPHAGE* Franchise

     17    0.6      22    0.6

KENALOG

     26    0.5      22    0.8

ORENCIA

     53    0.5      18    0.3

PARAPLATIN

     1    17.5      2    1.7

PLAVIX*

     1,015    0.4      988    0.5

PRAVACHOL

     47    0.5      128    1.0

REYATAZ

     138    0.6      122    0.6

SPRYCEL

     14    0.8      —      —  

SUSTIVA Franchise (a) (total revenue)

     147    0.7      115    0.5

ZERIT

     15    0.7      18    0.7

(a) Beginning in the third quarter of 2006, the SUSTIVA Franchise includes sales of SUSTIVA, as well as revenue of bulk efavirenz included in the combination therapy, ATRIPLA*. The estimated months on hand of the product in the U.S. wholesale distribution channel only include branded SUSTIVA inventory.

In October 2004, the U.S. pediatric exclusivity period for PARAPLATIN expired. The resulting entry of multiple generic competitors for PARAPLATIN led to a significant decrease in demand for PARAPLATIN, which in turn led to the months on hand of the product in the U.S. wholesaler distribution channel exceeding one month on hand at September 30, 2007, June 30, 2007, September 30, 2006 and June 30, 2006. The estimated value of PARAPLATIN inventory in the U.S. wholesaler distribution channel over one month on hand was approximately $0.1 million at September 30, 2007, $0.3 million at June 30, 2007,

 

22


$0.6 million at September 30, 2006 and $1.4 million at June 30, 2006. The Company no longer produces PARAPLATIN for the U.S. market and will continue to monitor PARAPLATIN wholesaler inventory levels until they have been depleted.

At September 30, 2006, the estimated value of PLAVIX* inventory in the U.S. wholesaler distribution channel exceeded one month on hand by approximately $41.4 million due to the at-risk launch of generic clopidogrel bisulfate in August 2006. Because of the large quantities of generic clopidogrel bisulfate shipped into the distribution channels before the preliminary injunction was granted ordering the halt of sales of generic clopidogrel bisulfate in late August 2006, demand for branded PLAVIX* decreased precipitously.

SPRYCEL was launched in the U.S. in July 2006. Consistent with standard practice at the time of a new product launch, the Company’s U.S. wholesalers built inventories of the product to meet expected demand and at September 30, 2006, the estimated value of SPRYCEL inventory in the U.S. wholesaler distribution channel exceeded one month on hand by approximately $0.6 million. The Company worked down wholesaler inventory levels to one month on hand or less in the subsequent quarter.

For all products other than ERBITUX* and ORENCIA, the Company determines the above months on hand estimates by dividing the estimated amount of the product in the U.S. wholesaler distribution channel by the estimated amount of out-movement of the product from the U.S. wholesaler distribution channel over a period of 31 days, all calculated as described below. Factors that may influence the Company’s estimates include generic competition, seasonality of products, wholesaler purchases in light of increases in wholesaler list prices, new product launches, new warehouse openings by wholesalers and new customer stockings by wholesalers. In addition, such estimates are calculated using third-party data, which represent their own record-keeping processes and as such, may also reflect estimates.

The Company maintains inventory management agreements (IMAs) with most of its U.S. Pharmaceuticals wholesalers, which account for nearly 100% of total gross sales of U.S. pharmaceutical products. Under the current terms of the IMAs, the Company’s three largest wholesaler customers provide the Company with weekly information with respect to inventory levels of product on hand and the amount of out-movement of products. These three wholesalers accounted for approximately 90% of total gross sales of U.S. Pharmaceuticals products in the third quarter of 2007. The inventory information received from these wholesalers excludes inventory held by intermediaries to whom they sell, such as retailers and hospitals, and excludes goods in transit to such wholesalers. The Company uses the information provided by these three wholesalers as of the Friday closest to quarter end to calculate the amount of inventory on hand for these wholesalers at the applicable quarter end. This amount is then increased by the Company’s estimate of goods in transit to these wholesalers based on the Company’s records of sales to these wholesalers, which have not been reflected in the weekly data provided by the wholesalers. Under the Company’s revenue recognition policy, sales are recorded when substantially all the risks and rewards of ownership are transferred, which in the U.S. Pharmaceuticals business is generally when product is shipped. In such cases, goods in transit to a wholesaler are owned by the applicable wholesaler and, accordingly, are reflected in the calculation of inventories in the wholesaler distribution channel. The Company determines the out-movement of a product from these wholesalers over a period of 31 days by using the most recent four weeks of out-movement of a product as provided by these wholesalers and extrapolating such amount to a 31 day basis. The Company estimates for each product, inventory levels on hand and out-movements for all its U.S. Pharmaceuticals business wholesaler customers, by adjusting the three largest wholesalers’ inventory levels and out-movements by a factor that approximates the other remaining wholesalers’ percentage share of total gross sales for such product in the U.S. In addition, the Company receives inventory information from these other wholesalers on a selective basis for certain key products.

The Company’s U.S. Pharmaceuticals business through the IMAs discussed above, has arrangements with substantially all of its direct wholesaler customers and requires those wholesalers to maintain inventory at levels that are no more than one month of their demand.

The Company distributes ORENCIA through distribution arrangements with multiple distributors. The above estimates of months on hand was calculated by dividing the inventories of ORENCIA held by these

 

23


distributors at the end of the quarter by the out-movement of the product over the last 31 day period, as reported by these distributors. The inventory on hand and out-movements reported by these distributors are a product of the distributors’ own record-keeping processes.

The Company sells ERBITUX* to intermediaries (such as wholesalers and specialty oncology distributors) and ships ERBITUX* directly to the end-users of the product who are the customers of those intermediaries. The Company also sells ERBITUX* to other distributors who then hold ERBITUX* inventory. The above estimate of months on hand was calculated by dividing the inventories of ERBITUX* held by the distributors for their own accounts as reported by the distributors as of the end of the quarter by the out-movements of the product reported by the distributors over the last 31 day period. The inventory levels reported by the distributors are a product of their record-keeping process.

 

24


International Pharmaceuticals, Nutritionals and Other Health Care

The following table sets forth for each of the Company’s key pharmaceutical products and other growth drivers sold by the Company’s International Pharmaceuticals reporting segment, including the top 15 pharmaceutical products sold in the Company’s major non-U.S. countries (based on 2006 net sales), and for each of the key products sold by the other reporting segments listed below, the percentage change in the Company’s estimated ultimate patient/consumer demand for the months of September 2007 and June 2007 compared to the same period in the prior year.

 

     % Change in Demand on a
Constant U.S. Dollar Basis
 
    

September 2007
vs.

September 2006

   

June 2007

vs.
June 2006

 

International Pharmaceuticals

    

ABILIFY* (total revenue)

   35     45  

AVAPRO*/AVALIDE*

   10     0  

BARACLUDE

   * *   * *

BUFFERIN*

   (64 )   (8 )

CAPOTEN

   (16 )   (21 )

DAFALGAN

   10     39  

EFFERALGAN

   17     29  

MAXIPIME

   (25 )   (18 )

MONOPRIL

   (8 )   (25 )

ORENCIA

   * *   * *

PERFALGAN

   1     31  

PLAVIX*

   10     0  

PRAVACHOL

   (46 )   (64 )

REYATAZ

   14     5  

SPRYCEL

   N/A     N/A  

SUSTIVA Franchise (total revenue)

   4     (1 )

TAXOL® (paclitaxel)

   (25 )   (29 )

VIDEX/VIDEX EC

   (20 )   (9 )

Nutritionals

    

ENFAMIL/ENFAGROW

   15     4  

NUTRAMIGEN

   8     (3 )

Other Health Care

    

ConvaTec

    

Ostomy

   (4 )   2  

Wound Therapeutics

   4     3  

Medical Imaging

    

CARDIOLITE

   (7 )   (2 )

 

** In excess of 200%

 

25


Estimated Inventory Months on Hand in the Distribution Channel

The following table sets forth for each of the Company’s key products sold by the reporting segments listed below, the net sales of the applicable product for each of the quarters ended September 30, 2007, June 30, 2007, September 30, 2006, and June 30, 2006 and the estimated number of months on hand of the applicable product in the direct customer distribution channel for the reporting segment as of the end of each of the four quarters. The estimates of months on hand for key products described below for the International Pharmaceuticals reporting segment are based on data collected for all of the Company’s significant business units outside of the U.S. Also described further below is information on non-key product(s) where the amount of inventory on hand at direct customers is more than approximately one month and the impact is not de minimis. For the other reporting segments, estimates are based on data collected for the U.S. and all significant business units outside of the U.S.

 

     September 30, 2007    June 30, 2007

Dollars in Millions

   Net Sales   

Months

On Hand

   Net Sales   

Months

On Hand

International Pharmaceuticals

           

ABILIFY* (total revenue)

   $ 91    0.6    $ 90    0.6

AVAPRO*/AVALIDE*

     133    0.5      127    0.5

BARACLUDE

     50    0.6      39    0.7

BUFFERIN*

     16    0.8      27    0.5

CAPOTEN

     26    0.8      25    0.9

DAFALGAN

     40    1.1      42    1.4

EFFERALGAN

     71    0.9      69    1.4

MAXIPIME

     30    0.7      39    0.8

MONOPRIL

     43    1.2      42    1.2

ORENCIA

     3    0.3      2    0.4

PERFALGAN

     56    0.6      65    0.5

PLAVIX*

     174    0.5      174    0.6

PRAVACHOL

     69    0.6      85    0.6

REYATAZ

     132    0.6      116    0.7

SPRYCEL

     29    0.4      21    0.4

SUSTIVA Franchise (a) (total revenue)

     86    0.5      86    0.5

TAXOL® (paclitaxel)

     101    0.6      91    0.6

VIDEX/VIDEX EC

     36    1.4      27    1.1

Nutritionals

           

ENFAMIL/ENFAGROW

     355    0.9      337    0.9

NUTRAMIGEN

     56    1.0      54    1.0

Other Health Care

           

ConvaTec

           

Ostomy

     147    0.9      150    0.9

Wound Therapeutics

     126    0.9      119    0.9

Medical Imaging

           

CARDIOLITE

     99    0.8      106    0.7

 

(a) Beginning in the third quarter of 2006, the SUSTIVA Franchise includes sales of SUSTIVA, as well as revenue of bulk efavirenz included in the combination therapy, ATRIPLA*. The estimated months on hand of the product in the distribution channel only include branded SUSTIVA inventory.

 

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     September 30, 2006    June 30, 2006

Dollars in Millions

   Net Sales   

Months

on Hand

   Net Sales   

Months

on Hand

International Pharmaceuticals

           

ABILIFY* (total revenue)

   $ 53    0.6    $ 57    0.6

AVAPRO*/AVALIDE*

     118    0.5      113    0.5

BARACLUDE

     8    0.9      5    1.0

BUFFERIN*

     28    0.5      31    0.5

CAPOTEN

     28    0.8      31    0.9

DAFALGAN

     35    1.1      37    1.1

EFFERALGAN

     62    0.9      62    0.9

MAXIPIME

     40    0.7      43    0.8

MONOPRIL

     34    1.0      48    1.1

ORENCIA

     —      —        —      —  

PERFALGAN

     48    0.6      51    0.6

PLAVIX*

     156    0.6      157    0.5

PRAVACHOL

     119    0.7      195    1.4

REYATAZ

     104    1.1      114    0.7

SPRYCEL

     —      —        —      —  

SUSTIVA

     73    0.5      78    0.5

TAXOL® (paclitaxel)

     135    0.6      145    0.5

VIDEX/VIDEX EC

     35    1.4      35    1.2

Nutritionals

           

ENFAMIL/ENFAGROW

     315    0.8      312    0.9

NUTRAMIGEN

     50    1.0      54    1.0

Other Health Care

           

ConvaTec

           

Ostomy

     139    0.9      141    1.0

Wound Therapeutics

     113    0.9      107    0.9

Medical Imaging

           

CARDIOLITE

     97    0.8      105    0.8

The above months on hand information represents the Company’s estimates of aggregate product level inventory on hand at direct customers divided by the expected demand for the applicable product. Expected demand is the estimated ultimate patient/consumer demand calculated based on estimated end-user consumption or direct customer out-movement data over the most recent 31 day period or other reasonable period. Factors that may affect the Company’s estimates include generic competition, seasonality of products, direct customer purchases in light of price increases, new product or product presentation launches, new warehouse openings by direct customers, new customer stockings by direct customers and expected direct customer purchases for governmental bidding situations.

The Company relies on a variety of methods to calculate months on hand for these reporting segments. Where available, the Company relies on information provided by third parties to determine estimates of aggregate product level inventory on hand at direct customers and expected demand. For the reporting segments listed above; however, the Company has limited information on direct customer product level inventory, end-user consumption and direct customer out-movement data. Further, the quality of third-party information, where available, varies widely. In some circumstances, such as the case with new products or seasonal products, such historical end-user consumption or out-movement information may not be available or applicable. In such cases, the Company uses estimated prospective demand. In cases where direct customer product level inventory, ultimate patient/consumer demand or out-movement data do not exist or are otherwise not available, the Company has developed a variety of other methodologies to calculate estimates of such data, including using such factors as historical sales made to direct customers and third-party market research data related to prescription trends and end-user demand.

 

27


As of September 30, 2007, June 30, 2007, September 30, 2006 and June 30, 2006, DAFALGAN, an analgesic product sold principally in Europe, had approximately 1.1 months, 1.4 months, 1.1 months, and 1.1 months of inventory on hand, respectively, at direct customers. The level of inventory on hand is due primarily to private pharmacists purchasing DAFALGAN approximately once every eight weeks and the seasonality of the product.

As of June 30, 2007, EFFERALGAN, an analgesic product sold principally in Europe, had approximately 1.4 months of inventory on hand, respectively, at direct customers. The level of inventory on hand is due primarily to private pharmacists purchasing EFFERALGAN approximately once every eight weeks and the seasonality of the product.

As of September 30, 2007, June 30, 2007, and June 30, 2006, MONOPRIL, a cardiovascular product, had approximately 1.2 months, 1.2 months and 1.1 months of inventory on hand, respectively, at direct customers. The levels of inventory on hand as of September 30, 2007 and June 30, 2007, is due primarily to initial stocking of a new, exclusive distributor in Poland and stocking in support of the launch of MONOPRIL in Poland in 2007. The level of inventory on hand as of June 30, 2006, was due primarily to supply of the product in support of its inclusion in a government program in Russia.

As of June 30, 2006, PRAVACHOL, a cardiovascular product, had approximately 1.4 months of inventory on hand, respectively, at direct customers. The increased level of inventory on hand was due primarily to an increase in orders from a significant direct customer in France.

As of September 30, 2006, REYATAZ, an antiviral product, had approximately 1.1 months on hand at direct customers. The increased level of inventory on hand is due primarily to government purchasing patterns in Brazil.

As of September 30, 2007, June 30, 2007, September 30, 2006 and June 30, 2006, VIDEX/VIDEX EC, an antiviral product, had approximately 1.4 months, 1.1 months, 1.4 months, and 1.2 months of inventory on hand at direct customers. The increased level of inventory on hand is due primarily to government purchasing patterns in Brazil. The Company is contractually obligated to provide VIDEX/VIDEX EC to the Brazilian government upon placement of an order for product by the government. Under the terms of the contract, the Company has no control over the inventory levels relating to such orders.

The Company continuously seeks to improve the quality of its estimates of months on hand of inventories held by its direct customers including thorough review of its methodologies and processes for calculation of these estimates and review and analysis of its own and third parties’ data used in such calculations. The Company expects that it will continue to review and refine its methodologies and processes for calculation of these estimates and will continue to review and analyze its own and third parties’ data in such calculations.

 

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