-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, UjYyjfYplx3z+BpSAtKaZT1lX4qFr6IkKiX0+hj4+j9ekeyNuAolIgn2Y4pzLsjv 1rrXm7A9WC6NJliLF6JPGQ== 0001193125-07-193626.txt : 20070831 0001193125-07-193626.hdr.sgml : 20070831 20070831101655 ACCESSION NUMBER: 0001193125-07-193626 CONFORMED SUBMISSION TYPE: 8-K/A PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20070726 ITEM INFORMATION: Results of Operations and Financial Condition ITEM INFORMATION: Financial Statements and Exhibits FILED AS OF DATE: 20070831 DATE AS OF CHANGE: 20070831 FILER: COMPANY DATA: COMPANY CONFORMED NAME: BRISTOL MYERS SQUIBB CO CENTRAL INDEX KEY: 0000014272 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 220790350 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 8-K/A SEC ACT: 1934 Act SEC FILE NUMBER: 001-01136 FILM NUMBER: 071093194 BUSINESS ADDRESS: STREET 1: 345 PARK AVE CITY: NEW YORK STATE: NY ZIP: 10154 BUSINESS PHONE: 2125464000 MAIL ADDRESS: STREET 1: 345 PARK AVE CITY: NEW YORK STATE: NY ZIP: 10154 FORMER COMPANY: FORMER CONFORMED NAME: BRISTOL MYERS CO DATE OF NAME CHANGE: 19891012 8-K/A 1 d8ka.htm FORM 8-K/A Form 8-K/A

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K/A

(Amendment No. 1)

CURRENT REPORT

Pursuant to Section 13 OR 15(d) of The Securities Exchange Act Of 1934

Date of Report (Date of earliest event reported): July 26, 2007

BRISTOL-MYERS SQUIBB COMPANY

(Exact Name of Registrant as Specified in its Charter)

 

Delaware   1-1136   22-079-0350
(State or Other Jurisdiction
of Incorporation)
  (Commission
File Number)
  (IRS Employer
Identification Number)

345 Park Avenue

New York, NY, 10154

(Address of Principal Executive Office)

Registrant’s telephone number, including area code: (212) 546-4000

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

¨ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 



Item 2.02.  Results of Operations and Financial Condition.

On July 26, 2007, Bristol-Myers Squibb Company (the “Company”) filed a Form 8-K furnishing its press release that announced the Company’s financial results for the second quarter of 2007 and incorporating it therein by reference. Also furnished and incorporated by reference as Exhibit 99.2 was certain supplemental information posted on the Company’s website at www.bms.com. This supplemental information has been revised to include net sales, months on hand, and estimated demand information for key products as of June 30, 2007 for the Company’s International Pharmaceutical, Nutritionals and Other Health Care reporting segments. Net sales and months on hand information is also provided as of March 31, 2007, June 30, 2006 and March 31, 2006. The revised supplemental information is furnished and incorporated by reference as Exhibit 99.2 to this Form 8-K/A.

 

Item 9.01.  Financial Statements and Exhibits.

(d) Exhibits.

 

99.2.    Certain supplemental information posted on Bristol-Myers Squibb Company’s website at www.bms.com


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

    BRISTOL-MYERS SQUIBB COMPANY
Dated: August 31, 2007     By:   /s/ Sandra Leung
      Name:   Sandra Leung
      Title:   Senior Vice President and General Counsel


EXHIBIT INDEX

 

Exhibit No.   

Description

99.2    Certain supplemental information posted on Bristol-Myers Squibb Company’s website at www.bms.com
EX-99.2 2 dex992.htm CERTAIN SUPPLEMENTAL INFORMATION Certain supplemental information

Exhibit 99.2

BRISTOL-MYERS SQUIBB COMPANY

NET SALES

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

Net Sales    2006     2007    % Change  
     1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year     1st Qtr     2nd Qtr     6 Months     3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Pharmaceuticals

   $ 3,700     $ 3,859     $ 7,559     $ 3,154     $ 10,713     $ 3,148     $ 13,861     $ 3,457     $ 3,851     $ 7,308                 —       -3 %

US Pharmaceuticals

     2,064       2,197       4,261       1,609       5,870       1,501       7,371       1,932       2,235       4,167                 2 %   -2 %

Primary Care

     1,409       1,441       2,850       819       3,669       648       4,317       1,090       1,344       2,434                 -7 %   -15 %

Oncology/Virology

     419       458       877       494       1,371       525       1,896       504       511       1,015                 12 %   16 %

Neuroscience

     231       280       511       262       773       297       1,070       298       327       625                 17 %   22 %

Immunoscience

     5       18       23       34       57       31       88       40       53       93                 194 %   *  

Europe and Middle East Medicines

     1,024       1,000       2,024       886       2,910       934       3,844       916       939       1,855                 -6 %   -8 %
                                   —      

Latin America/Canada

     288       303       591       300       891       306       1,197       297       311       608                 3 %   3 %

Asia/Pacific Medicines

     279       320       599       318       917       349       1,266       289       333       622                 4 %   4 %

Nutritionals

     565       582       1,147       582       1,729       618       2,347       606       620       1,226                 7 %   7 %

Other Health Care

     411       430       841       418       1,259       447       1,706       413       457       870                 6 %   3 %

ConvaTec

     230       262       492       265       757       291       1,048       254       286       540                 9 %   10 %

Medical Imaging

     181       168       349       153       502       156       658       159       171       330                 2 %   -5 %

Total Company

   $ 4,676     $ 4,871     $ 9,547     $ 4,154     $ 13,701     $ 4,213     $ 17,914     $ 4,476     $ 4,928     $ 9,404                 1 %   -1 %
% of Total Sales    2006     2007    Basis Point Change  
     1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year     1st Qtr     2nd Qtr     6 Months     3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Pharmaceuticals

     79.1 %     79.2 %     79.2 %     75.9 %     78.2 %     74.7 %     77.4 %     77.2 %     78.1 %     77.7 %               (110 )   (150 )

US Pharmaceuticals

     44.1 %     45.1 %     44.6 %     38.7 %     42.8 %     35.6 %     41.1 %     43.2 %     45.4 %     44.3 %               30     (30 )

Primary Care

     30.1 %     29.6 %     29.9 %     19.7 %     26.8 %     15.4 %     24.1 %     24.4 %     27.3 %     25.9 %               (230 )   (400 )

Oncology/Virology

     9.0 %     9.4 %     9.2 %     11.9 %     10.0 %     12.5 %     10.5 %     11.3 %     10.4 %     10.8 %               100     160  

Neuroscience

     4.9 %     5.7 %     5.3 %     6.3 %     5.6 %     7.0 %     6.0 %     6.7 %     6.6 %     6.6 %               90     130  

Immunoscience

     0.1 %     0.4 %     0.2 %     0.8 %     0.4 %     0.7 %     0.5 %     0.8 %     1.1 %     1.0 %               70     80  

Europe and Middle East Medicines

     21.9 %     20.5 %     21.2 %     21.3 %     21.2 %     22.2 %     21.5 %     20.5 %     19.1 %     19.7 %               (140 )   (150 )

Latin America/Canada

     6.2 %     6.2 %     6.2 %     7.2 %     6.5 %     7.3 %     6.7 %     6.6 %     6.3 %     6.5 %               10     30  

Asia/Pacific Medicines

     6.0 %     6.6 %     6.3 %     7.7 %     6.7 %     8.3 %     7.1 %     6.5 %     6.8 %     6.6 %               20     30  

Nutritionals

     12.1 %     12.0 %     12.0 %     14.0 %     12.6 %     14.7 %     13.1 %     13.5 %     12.6 %     13.0 %               60     100  

Other Health Care

     8.8 %     8.8 %     8.8 %     10.1 %     9.2 %     10.6 %     9.5 %     9.3 %     9.3 %     9.3 %               50     50  

ConvaTec

     4.9 %     5.4 %     5.2 %     6.4 %     5.5 %     6.9 %     5.8 %     5.7 %     5.8 %     5.8 %               40     60  

Medical Imaging

     3.9 %     3.4 %     3.6 %     3.7 %     3.7 %     3.7 %     3.7 %     3.6 %     3.5 %     3.5 %               10     (10 )
                                   —       —    

Total Company

     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %                

* In Excess of +/- 200%

 

1


BRISTOL-MYERS SQUIBB COMPANY

SEGMENT SALES AND COMPOSITION OF CHANGE IN SALES FOR TOTAL COMPANY

FOR THE PERIOD ENDED JUNE 30, 2007

($ in millions)

 

QUARTER-TO-DATE

          
     Pharmaceuticals     Nutritionals     Convatec     Medical
Imaging
   

Total

Company

 

Price Increases/(Decreases)

     1 %     2 %     —         —         1 %

Foreign Exchange

     2 %     3 %     4 %     1 %     2 %

Volume

     -3 %     2 %     5 %     1 %     -2 %
                                        

Total Change

     —         7 %     9 %     2 %     1 %
                                        

Total 2007 Period to Date Sales

   $ 3,851     $ 620     $ 286     $ 171     $ 4,928  

Total 2006 Period to Date Sales

   $ 3,859     $ 582     $ 262     $ 168     $ 4,871  

YEAR-TO-DATE

          
     Pharmaceuticals     Nutritionals     Convatec     Medical
Imaging
   

Total

Company

 

Price Increases/(Decreases)

     1 %     2 %     -1 %     -2 %     1 %

Foreign Exchange

     2 %     2 %     5 %     1 %     2 %

Volume

     -6 %     3 %     6 %     -4 %     -4 %
                                        

Total Change

     -3 %     7 %     10 %     -5 %     -1 %
                                        

Total 2007 Period to Date Sales

   $ 7,308     $ 1,226     $ 540     $ 330     $ 9,404  

Total 2006 Period to Date Sales

   $ 7,559     $ 1,147     $ 492     $ 349     $ 9,547  

 

2


BRISTOL-MYERS SQUIBB COMPANY

CONSOLIDATED STATEMENT OF EARNINGS

($ in millions, except per share amounts)

 

     2006     2007    % Change  
     1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year     1st Qtr     2nd Qtr     6 Months     3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Net Sales

   $ 4,676     $ 4,871     $ 9,547     $ 4,154     $ 13,701     $ 4,213     $ 17,914     $ 4,476     $ 4,928     $ 9,404                 1 %   -1 %

Cost of products sold

     1,476       1,568       3,044       1,465       4,509       1,447       5,956       1,392       1,549       2,941                 -1 %   -3 %

Marketing, selling and administrative

     1,238       1,181       2,419       1,189       3,608       1,311       4,919       1,158       1,209       2,367                 2 %   -2 %

Advertising and product promotion

     295       352       647       286       933       418       1,351       269       368       637                 5 %   -2 %

Research and development

     750       740       1,490       756       2,246       821       3,067       807       778       1,585                 5 %   6 %

Provision for restructuring, net

     1       3       4       2       6       53       59       37       7       44                 133 %   *  

Litigation (income)/expense, net

     (21 )     (14 )     (35 )     (9 )     (44 )     346       302       —         14       14                 200 %   140 %

Gain on sale of product assets

     (200 )     —         (200 )     —         (200 )     —         (200 )     —         (26 )     (26 )               —       87 %

Equity in net income of affiliates

     (93 )     (125 )     (218 )     (118 )     (336 )     (138 )     (474 )     (126 )     (128 )     (254 )               -2 %   -17 %

Other expense/(income), net

     37       56       93       (34 )     59       240       299       22       —         22                 -100 %   -76 %
                                                                                                        

Total expenses

     3,483       3,761       7,244       3,537       10,781       4,498       15,279       3,559       3,771       7,330                 0 %   1 %
                                                                                                        

Earnings/(Loss) Before Minority Interest and Income Taxes

     1,193       1,110       2,303       617       2,920       (285 )     2,635       917       1,157       2,074                 4 %   -10 %

Provision/(Benefit) for income taxes

     328       256       584       193       777       (167 )     610       86       257       343                 0 %   -41 %

Minority interest, net of taxes

     151       187       338       86       424       16       440       141       194       335                 4 %   -1 %
                                                                                                        

Net Earnings/(Loss)

   $ 714     $ 667     $ 1,381     $ 338     $ 1,719     $ (134 )   $ 1,585     $ 690     $ 706     $ 1,396                 6 %   1 %
                                                                                                        

Interest expense on conversion of convertible debt bonds, net of tax

     8       8       16       9       25       —   (1)     —   (2)     9       9       18                  
                                                                                                

Net Earnings/(Loss) used for diluted earnings per common share calculation

   $ 722     $ 675     $ 1,397     $ 347     $ 1,744     $ (134 )(1)   $ 1,585 (2)   $ 699     $ 715     $ 1,414                  
                                                                                                

Diluted Earnings/(Loss) per Common Share**

   $ 0.36     $ 0.34     $ 0.70     $ 0.17     $ 0.88     $ (0.07 )(1)   $ 0.81 (2)   $ 0.35     $ 0.36     $ 0.71                 6 %   1 %

Average Common Shares Outstanding - Diluted

     1,988       1,994       1,992       1,992       1,991       1,961 (1)     1,963 (2)     1,997       2,006       2,002                 1 %   1 %

Dividends declared per common share

   $ 0.28     $ 0.28     $ 0.56     $ 0.28     $ 0.84     $ 0.28     $ 1.12     $ 0.28     $ 0.28     $ 0.56                 —       —    

% of Net
Sales

   2006     2007    Basis Point Change  
   1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year     1st Qtr     2nd Qtr     6 Months     3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Gross Margin

     68.4 %     67.8 %     68.1 %     64.7 %     67.1 %     65.7 %     66.8 %     68.9 %     68.6 %     68.7 %               80     60  

Cost of products sold

     31.6 %     32.2 %     31.9 %     35.3 %     32.9 %     34.3 %     33.2 %     31.1 %     31.4 %     31.3 %               (80 )   (60 )

Marketing, selling and administrative

     26.5 %     24.2 %     25.3 %     28.6 %     26.3 %     31.1 %     27.5 %     25.9 %     24.5 %     25.2 %               30     (10 )

Advertising and product promotion

     6.3 %     7.2 %     6.8 %     6.9 %     6.8 %     9.9 %     7.5 %     6.0 %     7.5 %     6.8 %               30     0  

Research and development

     16.0 %     15.2 %     15.6 %     18.2 %     16.4 %     19.5 %     17.1 %     18.0 %     15.8 %     16.9 %               60     130  

Total expenses

     74.5 %     77.2 %     75.9 %     85.1 %     78.7 %     106.8 %     85.3 %     79.5 %     76.5 %     77.9 %               (70 )   200  

Earnings/(Loss) Before Minority Interest and Income Taxes

     25.5 %     22.8 %     24.1 %     14.9 %     21.3 %     -6.8 %     14.7 %     20.5 %     23.5 %     22.1 %               70     (200 )

Net Earnings/(Loss)

     15.3 %     13.7 %     14.5 %     8.1 %     12.5 %     -3.2 %     8.8 %     15.4 %     14.3 %     14.8 %               60     30  

Other Ratios

                                    

Effective Tax Rate

     27.5 %     23.1 %     25.4 %     31.3 %     26.6 %     58.6 %     23.1 %     9.4 %     22.2 %     16.5 %               (90 )   (890 )

Other
(Income)/
Expense, net

   2006     2007    % Change  
   1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year     1st Qtr     2nd Qtr     6 Months     3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Interest expense

   $ 116     $ 124     $ 240     $ 130     $ 370     $ 128     $ 498     $ 109     $ 107     $ 216                 -14 %   -10 %

Interest income

     (62 )     (65 )     (127 )     (74 )     (201 )     (73 )     (274 )     (53 )     (62 )     (115 )               5 %   9 %

Foreign exchange transaction (gains)/losses

     (12 )     23       11       (11 )     —         6       6       8       (5 )     3                 -122 %   -73 %

Other, net

     (5 )     (26 )     (31 )     (79 )     (110 )     179       69       (42 )     (40 )     (82 )               -54 %   -165 %
                                                                                                        
   $ 37     $ 56     $ 93     ($ 34 )   $ 59     $ 240     $ 299     $ 22     $ 0     $ 22                 -100 %   -76 %
                                                                                                        

* in excess of +/- 200%
** quarterly amounts may not add to the year-to-date totals due to rounding of individual calculations.
(1) as a result of the Q4 2006 net loss, Diluted Average Common Shares Outstanding and Loss per Common Share are equal to Basic Average Common Shares Outstanding and Loss per Common Share.
(2) assumed interest amount and the assumed conversion of convertible debt are not used for Diluted Earnings per Common Share calculation as the impact of convertible debt is anti-dilutive.

 

3


BRISTOL-MYERS SQUIBB COMPANY

WORLDWIDE NET SALES BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

     2006    2007    % Change  
     1st Qtr    2nd Qtr    6 Months    3rd Qtr    9 Months    4th Qtr    Year    1st Qtr    2nd Qtr    6 Months    3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Total Company

   $ 4,676    $ 4,871    $ 9,547    $ 4,154    $ 13,701    $ 4,213    $ 17,914    $ 4,476    $ 4,928    $ 9,404                1 %   -1 %

PHARMACEUTICALS

     3,700      3,859      7,559      3,154      10,713      3,148      13,861      3,457      3,851      7,308                —       -3 %

Cardiovascular

     1,917      1,907      3,824      1,239      5,063      1,093      6,156      1,475      1,763      3,238                -8 %   -15 %

Plavix

     986      1,145      2,131      630      2,761      496      3,257      938      1,189      2,127                4 %   —    

Pravachol

     536      323      859      192      1,051      146      1,197      135      132      267                -59 %   -69 %

Avapro/ Avalide

     233      280      513      277      790      307      1,097      270      297      567                6 %   11 %

Coumadin

     55      55      110      53      163      57      220      46      52      98                -5 %   -11 %

Virology

     468      524      992      532      1,524      580      2,104      590      608      1,198                16 %   21 %

Reyataz

     207      236      443      233      676      255      931      263      254      517                8 %   17 %

Sustiva Franchise***

     175      193      368      201      569      222      791      226      233      459                21 %   25 %

Baraclude

     11      14      25      22      47      36      83      45      59      104                *     *  

Oncology

     361      401      762      399      1,161      394      1,555      355      360      715                -10 %   -6 %

Erbitux

     138      172      310      175      485      167      652      160      162      322                -6 %   4 %

Taxol

     147      149      296      137      433      130      563      111      95      206                -36 %   -30 %

Sprycel

     —        —        —        11      11      14      25      21      35      56                —       —    

Affective (Psychiatric) Disorders

     323      376      699      354      1,053      404      1,457      408      458      866                22 %   24 %

Abilify**

     283      324      607      313      920      362      1,282      366      412      778                27 %   28 %

Immunoscience

     5      18      23      34      57      32      89      41      55      96                *     *  

Orencia

     5      18      23      34      57      32      89      41      55      96                *     *  

Other Pharmaceuticals

                                              

Efferalgan

     68      62      130      62      192      74      266      81      69      150                11 %   15 %

NUTRITIONALS

     565      582      1,147      582      1,729      618      2,347      606      620      1,226                7 %   7 %

Enfamil

     237      253      490      246      736      271      1,007      254      267      521                6 %   6 %

Enfagrow

     67      59      126      69      195      67      262      72      70      142                19 %   13 %

OTHER HEALTH CARE

     411      430      841      418      1,259      447      1,706      413      457      870                6 %   3 %

CONVATEC

     230      262      492      265      757      291      1,048      254      286      540                9 %   10 %

Ostomy

     123      141      264      139      403      151      554      130      150      280                6 %   6 %

Wound Therapeutics

     98      107      205      113      318      123      441      107      119      226                11 %   10 %

MEDICAL IMAGING

     181      168      349      153      502      156      658      159      171      330                2 %   -5 %

Cardiolite

     103      105      208      97      305      103      408      99      106      205                1 %   -1 %

* In excess of +/- 200%
** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc.

 

4


BRISTOL-MYERS SQUIBB COMPANY

DOMESTIC* NET SALES BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

    2006   2007   % Change     % Change in U.S. Total
Prescription****
 
    1st
Qtr
  2nd
Qtr
  6 Months   3rd
Qtr
  9 Months   4th
Qtr
  Year   1st
Qtr
  2nd
Qtr
  6 Months   3rd Qtr   9 Months   4th Qtr   Year   Qtr vs. Qtr     YTD vs. YTD     Qtr vs. Qtr     YTD vs. YTD  

Total Company

  $ 2,638   $ 2,806   $ 5,444   $ 2,170   $ 7,614   $ 2,115   $ 9,729   $ 2,505   $ 2,830   $ 5,335           1 %   -2 %    

PHARMACEUTICALS

    2,076     2,205     4,281     1,619     5,900     1,517     7,417     1,944     2,243     4,187           2 %   -2 %    

Cardiovascular

    1,341     1,330     2,671     752     3,423     616     4,039     1,045     1,279     2,324           -4 %   -13 %    

Plavix

    850     988     1,838     474     2,312     343     2,655     787     1,015     1,802           3 %   -2 %   1 %   -18 %

Pravachol

    302     128     430     73     503     50     553     57     47     104           -63 %   -76 %   -74 %   -82 %

Avapro/ Avalide

    139     167     306     159     465     182     647     163     170     333           2 %   9 %   -2 %   -2 %

Coumadin

    47     46     93     45     138     48     186     38     43     81           -7 %   -13 %   -16 %   -16 %

Virology

    259     270     529     292     821     327     1,148     319     323     642           20 %   21 %    

Reyataz

    119     122     241     129     370     144     514     143     138     281           13 %   17 %   13 %   15 %

Sustiva Franchise*****

    108     115     223     128     351     144     495     144     147     291           28 %   30 %   25 %   25 %

Baraclude

    9     9     18     14     32     18     50     17     20     37           122 %   106 %   77 %   98 %

Oncology

    159     187     346     201     547     195     742     182     187     369           —       7 %    

Erbitux

    136     172     308     173     481     165     646     158     160     318           -7 %   3 %   N/A     N/A  

Taxol

    4     4     8     2     10     2     12     4     4     8           —       —       N/A     N/A  

Sprycel

    —       —       —       11     11     11     22     10     14     24           —       —       N/A     N/A  

Affective (Psychiatric) Disorders

    237     286     523     266     789     302     1,091     305     333     638           16 %   22 %    

Abilify**

    231     267     498     260     758     294     1,052     293     322     615           21 %   23 %   13 %   13 %

Immunoscience

    5     18     23     34     57     31     88     40     53     93           194 %   * **    

Orencia

    5     18     23     34     57     31     88     40     53     93           194 %   * **   N/A     N/A  

Other Pharmaceuticals

                                   

Efferalgan

    —       —       —       —       —       —       —       —       —       —             —       —       N/A     N/A  

NUTRITIONALS

    247     282     529     267     796     295     1,091     274     275     549           -2 %   4 %    

Enfamil

    155     174     329     169     498     190     688     171     177     348           2 %   6 %   N/A     N/A  

Enfagrow

    —       —       —       —       —       —       —       —       —       —             —       —       N/A     N/A  

OTHER HEALTH CARE

    231     226     457     215     672     232     904     214     236     450           4 %   -2 %    

CONVATEC

    73     85     158     84     242     101     343     78     93     171           9 %   8 %    

Ostomy

    34     41     75     39     114     45     159     34     41     75           —       —       N/A     N/A  

Wound Therapeutics

    30     34     64     36     100     43     143     32     36     68           6 %   6 %   N/A     N/A  

MEDICAL IMAGING

    158     141     299     131     430     131     561     136     143     279           1 %   -7 %    

Cardiolite

    91     91     182     86     268     90     358     87     92     179           1 %   -2 %   N/A     N/A  

* This table presents Total Company sales on a legal entity source basis and segment and product sales on a country management reported basis. As a result, the sum of segment sales does not tie to Total Company sales.
** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** In excess of +/- 200%
**** The estimated total U.S. prescription change for the retail and mail order channels are calculated based on Next-Generation Prescription Services (NGPS) version 2.0 data on a weighted-average basis. NGPS data is provided by IMS Health, a supplier of market research for the pharmaceutical industry. The weighted-average basis reflects the fact that mail order prescriptions include a greater volume of product supplied compared to retail prescriptions, which on average are 90 days for mail order and 30 days for retail. The calculation is derived by multiplying NGPS mail order prescription data by a factor that approximates three and adding to this the NGPS retail prescriptions.
***** Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc. The change in U.S. total prescriptions growth for the Sustiva Franchise includes both branded Sustiva and Atripla prescription units.

 

5


BRISTOL-MYERS SQUIBB COMPANY

INTERNATIONAL* NET SALES BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

     2006    2007    % Change  
     1st Qtr    2nd Qtr    6 Months    3rd Qtr    9 Months    4th Qtr    Year    1st Qtr    2nd Qtr    6 Months    3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Total Company

   $ 2,038    $ 2,065    $ 4,103    $ 1,984    $ 6,087    $ 2,098    $ 8,185    $ 1,971    $ 2,098    $ 4,069                2 %   -1 %
PHARMACEUTICALS      1,624      1,654      3,278      1,535      4,813      1,631      6,444      1,513      1,608      3,121                -3 %   -5 %

Cardiovascular

     576      577      1,153      487      1,640      477      2,117      430      484      914                -16 %   -21 %

    Plavix

     136      157      293      156      449      153      602      151      174      325                11 %   11 %

    Pravachol

     234      195      429      119      548      96      644      78      85      163                -56 %   -62 %

    Avapro/ Avalide

     94      113      207      118      325      125      450      107      127      234                12 %   13 %

    Coumadin

     8      9      17      8      25      9      34      8      9      17                —       —    
Virology      209      254      463      240      703      253      956      271      285      556                12 %   20 %

    Reyataz

     88      114      202      104      306      111      417      120      116      236                2 %   17 %

    Sustiva Franchise****

     67      78      145      73      218      78      296      82      86      168                10 %   16 %

    Baraclude

     2      5      7      8      15      18      33      28      39      67                * **   * **
Oncology      202      214      416      198      614      199      813      173      173      346                -19 %   -17 %

    Erbitux

     2      —        2      2      4      2      6      2      2      4                —       100 %

    Taxol

     143      145      288      135      423      128      551      107      91      198                -37 %   -31 %

    Sprycel

     —        —        —        —        —        3      3      11      21      32                —       —    
Affective (Psychiatric) Disorders      86      90      176      88      264      102      366      103      125      228                39 %   30 %

    Abilify**

     52      57      109      53      162      68      230      73      90      163                58 %   50 %
Immunoscience      —        —        —        —        —        1      1      1      2      3                —       —    

    Orencia

     —        —        —        —        —        1      1      1      2      3                —       —    
Other Pharmaceuticals                                               

    Efferalgan

     68      62      130      62      192      74      266      81      69      150                11 %   15 %
NUTRITIONALS      318      300      618      315      933      323      1,256      332      345      677                15 %   10 %

    Enfamil

     82      79      161      77      238      81      319      83      90      173                14 %   7 %

    Enfagrow

     67      59      126      69      195      67      262      72      70      142                19 %   13 %
OTHER HEALTH CARE      180      204      384      203      587      215      802      199      221      420                8 %   9 %
CONVATEC      157      177      334      181      515      190      705      176      193      369                9 %   10 %

    Ostomy

     89      100      189      100      289      106      395      96      109      205                9 %   8 %

    Wound Therapeutics

     68      73      141      77      218      80      298      75      83      158                14 %   12 %
MEDICAL IMAGING      23      27      50      22      72      25      97      23      28      51                4 %   2 %

    Cardiolite

     12      14      26      11      37      13      50      12      14      26                —       —    

 


* This table presents Total Company sales on a legal entity source basis and segment and product sales on a country management reported basis. As a result, the sum of segment sales does not tie to Total Company sales.
** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** In excess of +/- 200%
**** Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc.

 

6


BRISTOL-MYERS SQUIBB COMPANY

U.S. PHARMACEUTICALS NET SALES

EXCLUDING ESTIMATED IMPACT OF LAUNCH OF GENERIC CLOPIDOGREL BISULFATE

($ in millions)

 

     2007    2006    % Change  
     Q2    Q2    Qtr vs. Qtr  

U.S Pharmaceuticals Net Sales

        

U.S Pharmaceuticals Net Sales as Reported

   $ 2,235    $ 2,197    2 %

Estimated Impact of Launch of Generic Clopidogrel Bisulfate

     50 to 100      —      —    
                    

U.S Pharmaceuticals Net Sales Excluding the Estimated Impact of Launch of Generic Clopidogrel Bisulfate

   $ 2,285 to $2,335    $ 2,197    4% to 6%  
                    

 

7


BRISTOL-MYERS SQUIBB COMPANY

GROSS MARGIN

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2007  
     Q1     Q2                 TOTAL YEAR  

Net Sales

   $ 4,476     $ 4,928         $ 9,404  
                            

Gross Profit

          

Gross Profit

   $ 3,084     $ 3,379         $ 6,463  

Specified items*

     16       13           29  
                            

Gross Profit Excluding Specified Items

   $ 3,100     $ 3,392         $ 6,492  
                            

Gross Margin %

          

Gross Margin %

     68.9 %     68.6 %         68.7 %

Specified items*

     0.4 %     0.2 %         0.3 %
                            

Gross Margin % Excluding Specified Items

     69.3 %     68.8 %         69.0 %
                            
     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Net Sales

   $ 4,676     $ 4,871     $ 4,154     $ 4,213     $ 17,914  
                                        

Gross Profit

          

Gross Profit

   $ 3,200     $ 3,303     $ 2,689     $ 2,766     $ 11,958  

Specified items*

     46       20       72       29       167  
                                        

Gross Profit Excluding Specified Items

   $ 3,246     $ 3,323     $ 2,761     $ 2,795     $ 12,125  
                                        

Gross Margin %

          

Gross Margin %

     68.4 %     67.8 %     64.7 %     65.6 %     66.8 %

Specified items*

     1.0 %     0.4 %     1.7 %     0.7 %     0.9 %
                                        

Gross Margin % Excluding Specified Items

     69.4 %     68.2 %     66.4 %     66.3 %     67.7 %
                                        

* Please refer to the Specified Item - QTD tab for detail of specified items.

 

8


BRISTOL-MYERS SQUIBB COMPANY

RESEARCH AND DEVELOPMENT EXPENSES

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2007
     Q1    Q2              TOTAL YEAR

Research and Development Expenses

   $ 807    $ 778          $ 1,585

Specified items*

     80      17            97
                          

Research and Development Expenses Excluding Specified Items

   $ 727    $ 761          $ 1,488
                          
     2006
     Q1    Q2    Q3    Q4    TOTAL YEAR

Research and Development Expenses

   $ 750    $ 740    $ 756    $ 821    $ 3,067

Specified items*

     18      1      17      49      85
                                  

Research and Development Expenses Excluding Specified Items

   $ 732    $ 739    $ 739    $ 772    $ 2,982
                                  

* Please refer to the Specified Item - QTD tab for detail of specified items.

 

9


BRISTOL-MYERS SQUIBB COMPANY

EFFECTIVE TAX RATE

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2007  
     Q1     Q2                 TOTAL YEAR  

Provision for Income Taxes

          

Provision for Income Taxes

   $ 86     $ 257         $ 343  

Specified items*

     79       5           84  
                            

Provision for Income Taxes Excluding Specified Items

   $ 165     $ 262         $ 427  
                            

Earnings Before Minority Interest and Provision for Income Taxes

   $ 917     $ 1,157         $ 2,074  

Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,050     $ 1,182         $ 2,232  

Effective Tax Rate

          

Effective Tax Rate

     9.4 %     22.2 %         16.5 %

Effective Tax Rate Excluding Specified Items

     15.7 %     22.2 %         19.1 %
     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Provision for Income Taxes

          

Provision/(Benefit) for Income Taxes

   $ 328     $ 256     $ 193     $ (167 )   $ 610  

Specified items*

     (49 )     (3 )     (34 )     196       110  
                                        

Provision for Income Taxes Excluding Specified Items

   $ 279     $ 253     $ 159     $ 29     $ 720  
                                        

Earnings/(Loss) Before Minority Interest and Provision for Income Taxes

   $ 1,193     $ 1,110     $ 617     $ (285 )   $ 2,635  

Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,081     $ 1,120     $ 670     $ 425     $ 3,296  

Effective Tax Rate

          

Effective Tax Rate

     27.5 %     23.1 %     31.3 %     58.6 %     23.1 %

Effective Tax Rate Excluding Specified Items

     25.8 %     22.6 %     23.7 %     6.8 %     21.8 %

* Please refer to the Specified Item - QTD tab for detail of specified items.

 

10


BRISTOL-MYERS SQUIBB COMPANY

EARNINGS BEFORE MINORITY INTEREST AND INCOME TAXES

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2007  
     Q1     Q2                 TOTAL YEAR  

Earnings Before Minority Interest and Provision for Income Taxes

   $ 917     $ 1,157         $ 2,074  

Specified items:

          

Upfront and milestone payments

     80       17           97  

Downsizing and streamlining of worldwide operations

     53       20           73  

Litigation matters

     —         14           14  

Gain on sale of product assets

     —         (26 )         (26 )
                            

Subtotal

     133       25           158  
                            

Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,050     $ 1,182         $ 2,232  
                            
     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Earnings / (Loss) Before Minority Interest and Provision for Income Taxes

   $ 1,193     $ 1,110     $ 617     $ (285 )   $ 2,635  

Specified items:

          

Gain on sale of product asset

     (200 )     —         —         —         (200 )

Litigation matters

     40       (14 )     (29 )     353       350  

Insurance recoveries

     (21 )     —         (9 )     (7 )     (37 )

Downsizing and streamlining of worldwide operations

     69       24       91       131       315  

Debt retirement costs

     —         —         —         220       220  

Claim for damages

     —         —         —         13       13  
                                        

Subtotal

     (112 )     10       53       710       661  
                                        

Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,081     $ 1,120     $ 670     $ 425     $ 3,296  
                                        

 

11


BRISTOL-MYERS SQUIBB COMPANY

DILUTED EARNINGS PER COMMON SHARE

EXCLUDING SPECIFIED ITEMS

 

     2007  
     Q1     Q2                 TOTAL YEAR *  

Diluted Earnings per Common Share

   $ 0.35     $ 0.36         $ 0.71  

Specified items:

          

Upfront and milestone payments

     0.03       0.01           0.03  

Downsizing and streamlining of worldwide operations

     0.02       0.01           0.03  

Gain on sale of product assets

     —         (0.01 )         (0.01 )

Tax item

     (0.02 )     —             (0.02 )
                            

Subtotal

     0.03       0.01           0.03  
                            

Diluted Earnings per Common Share Excluding Specified Items

   $ 0.38     $ 0.37         $ 0.74  
                            
     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR *  

Diluted Earnings / (Loss) per Common Share

   $ 0.36     $ 0.34     $ 0.17     $ (0.07 )   $ 0.81  

Specified items:

          

Gain on sale of product asset

     (0.06 )     —         —         —         (0.06 )

Litigation matters

     0.01       —         (0.01 )     0.14       0.14  

Insurance recoveries

     (0.01 )     —         —         —         (0.01 )

Downsizing and streamlining of worldwide operations / other

     0.02       0.01       0.04       0.05       0.12  

Debt retirement costs

     —         —         —         0.07       0.07  

Tax item

     —         —         0.02       —         0.02  
                                        

Subtotal

     (0.04 )     0.01       0.05       0.26       0.28  
                                        

Diluted Earnings per Common Share Excluding Specified Items

   $ 0.32     $ 0.35     $ 0.22     $ 0.19     $ 1.09  
                                        

* quarterly amounts may not add to the annual total due to rounding of individual calculations.

 

12


BRISTOL-MYERS SQUIBB COMPANY

SPECIFIED ITEMS

FOR THE THREE MONTHS ENDED JUNE 30, 2007 AND 2006

($ in millions)

Three months ended June 30, 2007

 

    

Cost of

products
sold

  

Research and

development

  

Provision for

restructuring, net

  

Litigation settlement

expense, net

  

Gain on sale of

product assets

    Total  

Litigation Matters:

                

Litigation settlement

   $ —      $ —      $ —      $ 14    $ —       $ 14  

Other:

                

Upfront and milestone payments

     —        17      —        —        —         17  

Accelerated depreciation

     13      —        —        —        —         13  

Downsizing and streamlining of worldwide operations

     —        —        7      —        —         7  

Gain on sale of product assets

     —        —        —        —        (26 )     (26 )
                                            
   $ 13    $ 17    $ 7    $ 14    $ (26 )     25  
                                      

Income taxes on items above

                   (5 )
                      

Reduction to Net Earnings

                 $ 20  
                      

Three months ended June 30, 2006

 

    

Cost of

products

sold

  

Research and

development

  

Provision for

restructuring, net

   Litigation income, net     Total  

Litigation Matters:

             

Commercial litigation

   $ —      $ —      $ —      $ (14 )   $ (14 )

Other:

             

Accelerated depreciation

     20      1      —        —         21  

Downsizing and streamlining of worldwide operations

     —        —        3      —         3  
                                     
   $ 20    $ 1    $ 3    $ (14 )     10  
                               

Income taxes on items above

                3  
                   

Reduction to Net Earnings from Continuing Operations

              $ 13  
                   

 

13


BRISTOL-MYERS SQUIBB COMPANY

SPECIFIED ITEMS

FOR THE SIX MONTHS ENDED JUNE 30, 2007 AND 2006

($ in millions)

Six months ended June 30, 2007

 

     Cost of
products
sold
   Research and
development
   Provision for
restructuring, net
   Litigation settlement
expense, net
   Gain on sale of
product assets
    Total  
Litigation Matters:                 

Litigation settlement

   $ —      $ —      $ —      $ 14    $ —       $ 14  
Other:                 

Upfront and milestone payments

     —        97      —        —        —         97  

Downsizing and streamlining of worldwide operations

     —        —        44      —        —         44  

Accelerated depreciation

     29      —        —        —        —         29  

Gain on sale of product assets

     —        —        —        —        (26 )     (26 )
                                            
   $ 29    $ 97    $ 44    $ 14    $ (26 )     158  
                                      

Income taxes on items above

                   (45 )

Change in estimate for taxes on a prior year specified item

                   (39 )
                      

Reduction to Net Earnings

                 $ 74  
                      

Six months ended June 30, 2006

 

     Cost of
products
sold
   Marketing selling and
administrative
   Research and
development
   Provision for
restructuring, net
   Litigation
income, net
    Gain on sale of
product asset
    Other
expense, net
   Total  
Litigation Matters:                      

Insurance recovery

   $ —      $ —      $ —      $ —      $ (21 )   $ —       $ —      $ (21 )

Commercial litigations

     —        —        —        —        (14 )     —         40      26  
                                                           
     —        —        —        —        (35 )     —         40      5  
Other:                      

Accelerated depreciation, asset impairment and contract termination

     66      4      1      —        —         —         —        71  

Downsizing and streamlining of worldwide operations

     —        —        —        4      —         —         —        4  

Upfront and milestone payments

     —        —        18      —        —         —         —        18  

Gain on sale of product asset

     —        —        —        —        —         (200 )     —        (200 )
                                                           
   $ 66    $ 4    $ 19    $ 4    $ (35 )   $ (200 )   $ 40      (102 )
                                                     

Income taxes on items above

                        52  

Minority interest, net of taxes

                        (13 )
                           

Increase to Net Earnings from Continuing Operations

                      $ (63 )
                           

 

14


BRISTOL-MYERS SQUIBB COMPANY

SELECT BALANCE SHEET INFORMATION

($ in millions)

 

    

March 31,

2006

  

June 30,

2006

  

September 30,

2006

  

December 31,

2006

   

March 31,

2007

  

June 30,

2007

  

September 30,

2007

  

December 31,

2007

Cash, cash equivalents and marketable debt securities

   $ 5,281    $ 5,357    $ 5,505    $ 4,013     $ 4,012    $ 4,646      

Short-term borrowings

     234      189      630      187       241      256      

Long-term debt

     8,278      8,239      7,837      7,248       7,132      6,978      
                                                

Net debt

   $ 3,231    $ 3,071    $ 2,962    $ 3,422     $ 3,361    $ 2,588      
                                                

Receivables, net of allowances

   $ 3,236    $ 3,326    $ 2,945    $ 3,247     $ 3,381    $ 3,632      

Stockholders’ equity

     11,556      11,712      11,589      9,991 (1)     10,261      10,762      

Capital expenditures and capitalized software (for the quarter ended)

     202      160      199      224       202      206      

(1) Includes the impact of the adoption of SFAS 158, “Employers’ Accounting for Defined Benefit Pension and Other Postretirement Plans - an amendment of FASB Statements No. 87, 88, 106 and 132(R)”

 

15


BRISTOL-MYERS SQUIBB COMPANY

2007 FULL YEAR PROJECTED DILUTED EPS

EXCLUDING PROJECTED SPECIFIED ITEMS

 

     Full Year 2007  

Projected Diluted Earnings per Common Share

   $ 1.35 to $1.45  

Projected Specified Items:

  

Upfront and milestone payments

     0.06  

Downsizing and streamlining of worldwide operations

     0.05  

Gain on sale of product assets

     (0.09 )

Tax item

     (0.02 )
        

Total

     —    
        

Projected Diluted Earnings per Common Share Excluding Specified Items

   $ 1.35 to $1.45  
        

2007 and 2008 Gross Margin/Research and Development/Tax Rate Projections Excluding Specified Items

Gross margin on a GAAP basis for the six months ended June 30, 2007 was 68.7%, which included specified items of $29 million and had a 0.3% adverse impact on gross margin in aggregate. On a non-GAAP basis, for the six months ended June 30, 2007 gross margin was 69.0%. On a non-GAAP basis, based on historical trends in 2006 and for the six months ended June 30, 2007 the Company projects gross margin for the full year 2007 to be at least 100 basis points higher than 2006 and for the full year 2008 to improve slightly compared to the full year 2007 estimate. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on gross margin. See Gross Margin non comparable tab.

Research and development expenses on a GAAP basis for the six months ended June 30, 2007 were $1,585 million, which included specified items of $97 million. On a non-GAAP basis, for the six months ended June 30, 2007 research and development expenses were $1,488 million. On a non-GAAP basis, based on historical trends in 2006 and for the six months ended June 30, 2007 the Company projects research and development expenses for the full year 2007 to increase in the mid single digit range compared to 2006 and for the full year 2008 to increase in the mid single digit range compared to the full year 2007 estimate. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on research and development. See R&D non comparable tab.

The effective tax rate on a GAAP basis for the six months ended June 30, 2007 was 16.5%, which included specified items of $84 million in the tax provision, and had a 2.6% favorable impact on the effective tax rate in aggregate. On a non-GAAP basis, for the six months ended June 30, 2007 effective tax rate was 19.1%. On a non-GAAP basis, based on historical trends in 2006 and for the six months ended June 30, 2007 the Company projects effective tax rate for the full year 2007 to be in the 20% range and for the full year 2008 to be in the 22% to 24% range. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on the tax rate. See Tax Rate non comparable tab.

The GAAP results for the full year 2007 and 2008 would include specified items that may occur and impact results. These specified items could include charges and recoveries relating to significant legal proceedings, debt retirement costs and other charges related to new transactions, upfront and milestone payments, copromotion or alliance charges and charges for in-process research and development related to new external development transactions, gains or losses from asset disposals, restructuring activities and significant tax events. For a fuller discussion of certain of the litigation and other matters that could impact full year GAAP results, as well as the use of non-GAAP financial information, see Bristol-Myers Squibb Company Reports Financial Results For The Second Quarter of 2007, July 26, 2007, including “Outlook for 2007 and 2008” and “Use of Non-GAAP Financial Information” therein.

 

16


BRISTOL-MYERS SQUIBB COMPANY

ESTIMATED MONTHS ON HAND OF TOP 15 U.S. PHARMACEUTICAL PRODUCTS

IN THE U.S. WHOLESALER DISTRIBUTION CHANNEL

The following tables sets forth, for each of the Company’s top 15 pharmaceutical products (based on 2006 annual net sales) sold by the Company’s U.S. Pharmaceuticals business, the U.S. Pharmaceuticals net sales and the estimated number of months on hand of the applicable product in the U.S. wholesaler distribution channel for the quarters ended June 30, 2007 and 2006 and March 31, 2007 and 2006.

 

    June 30, 2007   June 30, 2006   March 31, 2007   March 31, 2006
   

Net

Sales

 

Months on

Hand

 

Net

Sales

 

Months on

Hand

 

Net

Sales

 

Months on

Hand

 

Net

Sales

 

Months on

Hand

    (Dollars in Millions)       (Dollars in Millions)       (Dollars in Millions)       (Dollars in Millions)    
               

Abilify (total revenue)

  $ 322   0.4   $ 267   0.5   $ 293   0.4   $ 231   0.5

Avapro/Avalide

    170   0.4     167   0.5     163   0.4     139   0.4

Baraclude

    20   0.7     9   0.7     17   0.6     9   1.0

Coumadin

    43   0.7     46   0.8     38   0.7     47   0.6

Erbitux (a)

    160   0.4     172   —       158   0.3     136   —  

Glucophage Franchise

    17   0.6     22   0.6     21   0.6     25   0.7

Kenalog

    26   0.5     22   0.8     18   0.5     23   0.7

Orencia (b)

    53   0.5     18   0.3     40   0.3     5   0.9

Paraplatin

    1   17.5     2   1.7     5   13.8     7   1.2

Plavix

    1,015   0.4     988   0.5     787   0.6     850   0.4

Pravachol

    47   0.5     128   1.0     57   0.6     302   0.4

Reyataz

    138   0.6     122   0.6     143   0.7     119   0.6

Sprycel

    14   0.8     —     —       10   0.7     —     —  

Sustiva Franchise (c) (total revenue)

    147   0.7     115   0.5     144   0.7     108   0.5

Zerit

    15   0.7     18   0.7     12   0.6     19   0.7

For all products other than Erbitux and Orencia, the Company determines the above months on hand estimates by dividing the estimated amount of the product in the U.S. wholesaler distribution channel by the estimated amount of out-movement of the product from the U.S. wholesaler distribution channel over a period of 31 days, all calculated as described below. Factors that may influence the Company’s estimates include generic competition, seasonality of products, wholesaler purchases in light of increases in wholesaler list prices, new product launches, new warehouse openings by wholesalers and new customer stockings by wholesalers. In addition, such estimates are calculated using third-party data, which represent their own record-keeping processes and as such, may also reflect estimates.

Estimates of product in the wholesaler distribution channel and out-movement are based on weekly information received directly from third-parties, and excludes any inventory held by intermediaries such as retailers and hospitals, and excludes goods in transit to such wholesalers. The Company determines the amount of out-movement of a product over a period of 31 days by using the most recent out-movement of a product as provided by these third parties, adjusted to reflect the Company’s estimate of goods in transit to these wholesalers. The Company estimates the amount of goods in transit by using information provided by these wholesalers with respect to their open orders and the Company’s records of sales to these wholesalers with respect to such open orders.

 


(a) In the first and second quarter of 2006, the Company sold Erbitux to intermediaries (such as wholessalers and specialty oncology distributors) and shipped Erbitux directly to the end-users of the product who are the customers of those intermediaries. Beginning in the third quarter of 2006, the Company expanded its distribution model to include two distributors who then held Erbitux inventory. One additional distributor was added for Erbitux in the first quarter of 2007. The Company recognizes revenue upon such shipment consistent with its revenue recognition policy. The above estimate of months on hand was calculated by dividing the inventories of Erbitux held by the distributors for their own accounts as reported by the distributors as of the end of the quarter by the out-movements of the product reported by the distributors over the last 31 day period. The inventory levels reported by the distributors are a product of their record-keeping process.
(b) Orencia was launched in February 2006. From launch through the second quarter of 2006, the Company distributed Orencia through an exclusive distribution arrangement with a single distributor. Following approval of the supplemental Biologics License Application that allows a third party to manufacture Orencia at an additional site, the exclusive distribution arrangement terminated on July 17, 2006 and the Company expanded its distribution network for Orencia to multiple distributors. The above estimates of months on hand was calculated by dividing the inventories of Orencia held by these distributors at the end of the quarter by the out-movement of the product over the last 31 day period, as reported by these distributors. The inventory on hand and out-movements reported by these distributors are a product of the distributors’ own record-keeping process.
(c) Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. The estimated months on hand of the product in the U.S. wholesale distribution channel only include branded Sustiva inventory.

 

17


BRISTOL-MYERS SQUIBB COMPANY

ESTIMATED MONTHS ON HAND OF TOP INTERNATIONAL PHARMACEUTICAL

AND WORLDWIDE NON-PHARMACEUTICAL PRODUCTS

The following table, which was posted on the Company’s website and filed on Form 8-K on May 31, 2007, sets forth for each of the Company’s key products sold by the businesses listed below, the net sales of the applicable product for each of the quarters ended March 31, 2007, December 31, 2006, March 31, 2006 and December 31, 2005, and the estimated number of months on hand of the applicable product in the direct customer distribution channel for the business as of the end of each of the four quarters. The estimates of months on hand for key products described below for the International Pharmaceuticals business are based on data collected for all of the Company’s significant business units outside of the U.S. For the other non-Pharmaceuticals reporting segments, estimates are based on data collected for the U.S. and all significant business units outside of the U.S.

 

    March 31, 2007   December 31, 2006   March 31, 2006   December 31, 2005
   

Net

Sales

  Months on
Hand
 

Net

Sales

  Months on
Hand
 

Net

Sales

  Months on
Hand
 

Net

Sales

  Months on
Hand
    (Dollars in Millions)       (Dollars in Millions)       (Dollars in Millions)       (Dollars in Millions)    

International Pharmaceuticals

               

Abilify (total revenue)

  $ 73   0.6   $ 68   0.7   $ 52   0.6   $ 49   0.6

Avapro/Avalide

    107   0.5     125   0.6     94   0.5     109   0.6

Baraclude

    28   0.7     18   0.8     2   1.1     1   —  

Bufferin

    24   0.5     32   0.5     22   0.6     36   0.7

Capoten

    26   0.8     31   0.8     35   0.8     38   0.8

Dafalgan

    44   1.2     40   1.0     37   1.4     34   1.2

Efferalgan

    81   1.1     74   0.7     68   1.2     74   1.0

Maxipime

    29   0.5     33   0.6     40   0.8     48   0.8

Monopril

    36   0.8     35   0.9     46   1.1     43   0.9

Perfalgan

    58   0.5     54   0.5     46   0.6     43   0.6

Plavix

    151   0.5     153   0.6     136   0.5     155   0.6

Pravachol

    78   0.6     96   0.8     234   1.5     218   0.8

Reyataz

    120   0.9     111   1.0     88   0.6     78   0.6

Sustiva Franchise (a)

    82   0.5     78   0.5     67   0.5     68   0.6

Taxol

    107   0.7     128   0.7     143   0.6     176   0.8

Videx/Videx EC

    27   1.1     29   1.4     31   0.8     34   0.9

Nutritionals

               

Enfamil/Enfagrow

    326   0.8     338   0.9     304   0.9     330   1.0

Nutramigen

    52   0.9     54   1.0     48   1.0     48   1.1

Other Health Care

               

ConvaTec

               

Ostomy

    130   0.9     151   1.0     123   0.9     145   1.0

Wound Therapeutics

    107   0.9     123   1.0     98   0.9     112   0.9

Medical Imaging

               

Cardiolite

    99   0.7     103   0.9     103   0.8     100   1.0

(a) Beginning in the third quarter of 2006, the SUSTIVA Franchise includes sales of SUSTIVA, as well as revenue of bulk efavirenz included in the combination therapy, ATRIPLA. The estimated months on hand of the product in the distribution channel only include branded SUSTIVA inventory.

The above months on hand information represents the Company’s estimates of aggregate product level inventory on hand at direct customers divided by the expected demand for the applicable product. Expected demand is the estimated ultimate patient/consumer demand calculated based on estimated end-user consumption or direct customer out-movement data over the most recent 31 day period or other reasonable period. Factors that may affect the Company’s estimates include generic competition, seasonality of products, direct customer purchases in light of price increases, new product or product presentation launches, new warehouse openings by direct customers, new customer stockings by direct customers and expected direct customer purchases for governmental bidding situations.

 

18


U.S. Pharmaceuticals

Estimated End-User Demand

The following tables set forth for each of the Company’s top 15 pharmaceutical products (based on 2006 annual net sales) sold by the U.S. Pharmaceuticals business, for the three months ended June 30, 2007 compared to the same periods in the prior year: (i) changes in reported U.S. net sales for the period; (ii) estimated total U.S. prescription change for the retail and mail order channels calculated by the Company based on NGPS version 2.0 data on a weighted average basis; and (iii) the estimated U.S. therapeutic category share of the applicable product calculated by the Company based on NGPS version 2.0 data on a weighted-average basis. Prior year prescription data has been adjusted to conform to the NGPS version 2.0 data.

 

     Three Months Ended June 30, 2007     Month Ended June 30, 2007  
     Change
in U.S.
Net Sales(a)
    Change in U.S.
Total
Prescriptions(b)
   

Estimated TRx

Therapeutic

Category
Share (b, c)

 

ABILIFY* (total revenue)

   21 %   13 %   13 %

AVAPRO*/AVALIDE*

   2     (2 )   13  

BARACLUDE

   122     77     27  

COUMADIN

   (7 )   (16 )   14  

ERBITUX* (d)

   (7 )   N/A     N/A  

GLUCOPHAGE* Franchise

   (23 )   (33 )   1  

KENALOG (e)

   18     N/A     N/A  

ORENCIA(d)

   194     N/A     N/A  

PARAPLATIN (d)

   (50 )   N/A     N/A  

PLAVIX*

   3     1     86  

PRAVACHOL

   (63 )   (74 )   1  

REYATAZ (f)

   13     13     19  

SPRYCEL (g)

   —       —       5  

SUSTIVA Franchise (f, h) (total revenue)

   28     25     35  

ZERIT

   (17 )   (27 )   4  
     Three Months Ended June 30, 2006     Month Ended June 30, 2006  
     Change in
U.S. Net
Sales(a)
    Change in U.S.
Total
Prescriptions(b)
    Estimated TRx
Therapeutic
Category
Share(b, c)
 

ABILIFY* (total revenue)

   34 %   22 %   12 %

AVAPRO*/AVALIDE*

   6     2     14  

BARACLUDE

   80     * *   20  

COUMADIN

   10     (21 )   17  

ERBITUX* (d)

   77     N/A     N/A  

GLUCOPHAGE* Franchise

   (50 )   (51 )   1  

KENALOG (e)

   47     N/A     N/A  

ORENCIA (d)

   —       N/A     N/A  

PARAPLATIN (d)

   * *   N/A     N/A  

PLAVIX*

   20     12     87  

PRAVACHOL

   (64 )   (59 )   1  

REYATAZ (f)

   24     13     19  

SPRYCEL (g)

   —       —       —    

SUSTIVA (f)

   19     4     31  

ZERIT

   (31 )   (33 )   6  

(a) Reflects percentage change in net sales in dollar terms, including change in average selling prices and wholesaler buying patterns.

 

19


(b) Derived by multiplying NGPS mail order prescription data by a factor that approximates three and adding to this the NGPS retail prescriptions.

 

(c) The therapeutic categories are determined by the Company as those products considered to be in direct competition with the Company’s own products. The products listed above compete in the following therapeutic categories: ABILIFY* (antipsychotics), AVAPRO*/AVALIDE* (angiotensin receptor blockers), BARACLUDE (oral antiviral agent), COUMADIN (warfarin), ERBITUX* (oncology), GLUCOPHAGE* Franchise (oral antidiabetics), KENALOG (intra-articular/intramuscular steroid), ORENCIA (fusion protein), PARAPLATIN (carboplatin), PLAVIX* (antiplatelet agents), PRAVACHOL (HMG CoA reductase inhibitors), REYATAZ and the SUSTIVA Franchise (antiretrovirals - third agents excluding NORVIR* and TRIZIVIR*), SPRYCEL (TKIs for leukemia), and ZERIT (nucleoside reverse transcriptase inhibitors).

 

(d) ERBITUX*, ORENCIA and PARAPLATIN are parenterally administered products and do not have prescription-level data as physicians do not write prescriptions for these products. The Company believes therapeutic category share information provided by third parties for these products may not be reliable and accordingly, none is presented here.

 

(e) The Company does not have prescription level data because the product is not dispensed through a retail pharmacy. The Company believes therapeutic category share information provided by third parties for this product may not be reliable and accordingly, none is presented here.

 

(f) REYATAZ and the SUSTIVA Franchise have been recalculated as a percentage share of antiretrovirals – third agents excluding NORVIR* and TRIZIVIR*.

 

(g) SPRYCEL was launched in the U.S. in July 2006.

 

(h) Beginning in the third quarter of 2006, SUSTIVA Franchise (total revenue) includes sales of SUSTIVA, as well as revenue of bulk efavirenz included in the combination therapy, ATRIPLA*. The therapeutic category share information and change in U.S. total prescriptions growth for SUSTIVA Franchise (antiretrovirals – third agents excluding NORVIR* and TRIZIVIR*) includes both branded SUSTIVA and ATRIPLA* prescription units.

 

** In excess of 200%.

The Company is reporting REYATAZ’s estimated TRx category share within the antiretrovirals - third agents (excluding NORVIR* and TRIZIVIR*) category rather than the protease inhibitors (excluding NORVIR*) category. The Company believes that the antiretrovirals - third agents (excluding NORVIR* and TRIZIVIR*) category more closely reflects the use of protease inhibitors, which has evolved and competes with other products within the antiretrovirals - third agents (excluding NORVIR* and TRIZIVIR*) category. The historical trends of growth in REYATAZ’s estimated TRx category share between the two categories are not materially different.

On July 23, 2007, IMS issued a Product News bulletin announcing that it had revised its previously issued projected prescription and unit volumes for PLAVIX* and Apotex’s generic clopidogrel bisulfate product, which IMS had overstated for the months August 2006 through June 2007 due to market events surrounding the at-risk launch of generic clopidogrel bisulfate. Due to these unique circumstances, the high degree of volatility and the compressed timeframe of these events, IMS applied a custom approach to estimate PLAVIX* and generic clopidogrel bisulfate product and market volumes beginning in July 2007.

The IMS overstatement of PLAVIX* prescription and unit volumes did not impact the Company’s financial results or its reported net sales for PLAVIX* for the quarters ended September 30, 2006, December 31, 2006 or March 31, 2007.

 

20


The following table sets forth the Company’s (i) previously reported estimated prescription change data and estimated therapeutic category share based on National Prescription Audit (NPA) data for the quarters ended September 30, 2006 and December 31, 2006; (ii) previously reported estimated prescription change data and estimated therapeutic category share based on NGPS version 2.0 data for the quarter ended March 31, 2007; and (iii) revised estimated prescription change data and estimated therapeutic category share based on revised NGPS version 2.0 data using the IMS custom approach.

 

     PLAVIX*    

Clopidogrel Bisulfate

(Branded and Generic)

 
    

As Reported

(NPA Data)

   

Revised

(NGPS v2 Data)

   

As Reported

(NPA Data)

   

Revised

(NGPS v2 Data)

 

Change in U.S. Total Prescriptions

        

Three Months Ended March 31, 2007(a)

   (28 )%   (36 )%   18 %   9 %

Three Months Ended December 31, 2006

   (64 )   (70 )   14     11  

Three Months Ended September 30, 2006

   (32 )   (36 )   14     11  

Twelve Months Ended December 31, 2006

   (18 )   (21 )   14     12  

Nine Months Ended September 30, 2006

   (2 )   (4 )   N/A     N/A  

Estimated TRx Therapeutic Category Share

        

Month Ended March 31, 2007(a)

   65     62     N/A     N/A  

Month Ended December 31, 2006

   34     29     N/A     N/A  

Month Ended September 30, 2006

   23     19     N/A     N/A  

(a) NGPS version 2.0 data

The above IMS overstated data also impacted the Company’s previously reported estimate of the adverse effect of the at-risk launch of generic clopidogrel bisulfate of $300 million to $350 million for the three months ended March 31, 2007. Based on the revised data issued by IMS, the Company now estimates the adverse effect of the at-risk launch of generic clopidogrel bisulfate to be $200 million to $250 million for the three months ended March 31, 2007.

The estimated prescription change data and estimated therapeutic category share reported throughout this Form 10-Q only include information from the retail and mail order channels and do not reflect information from other channels, such as hospitals, institutions and long-term care, among others. The data provided by IMS are a product of IMS’ own record-keeping processes and are estimates based on IMS’ sampling procedures, subject to the inherent limitations of estimates based on sampling.

Estimated Inventory Months on Hand in the Distribution Channel

The following tables set forth for each of the Company’s top 15 pharmaceutical products (based on 2006 annual net sales) sold by the Company’s U.S. Pharmaceuticals business, the U.S. Pharmaceuticals net sales and the estimated number of months on hand of the applicable product in the U.S. wholesaler distribution channel for the quarters ended June 30, 2007 and 2006 and March 31, 2007 and 2006.

 

     June 30, 2007    June 30, 2006

Dollars in Millions

   Net Sales    Months on
Hand
   Net Sales    Months on
Hand

ABILIFY* (total revenue)

   $ 322    0.4    $ 267    0.5

AVAPRO*/AVALIDE*

     170    0.4      167    0.5

BARACLUDE

     20    0.7      9    0.7

COUMADIN

     43    0.7      46    0.8

ERBITUX*

     160    0.4      172    —  

GLUCOPHAGE* Franchise

     17    0.6      22    0.6

KENALOG

     26    0.5      22    0.8

ORENCIA

     53    0.5      18    0.3

PARAPLATIN

     1    17.5      2    1.7

PLAVIX*

     1,015    0.4      988    0.5

PRAVACHOL

     47    0.5      128    1.0

REYATAZ

     138    0.6      122    0.6

SPRYCEL

     14    0.8      —      —  

SUSTIVA Franchise (a) (total revenue)

     147    0.7      115    0.5

ZERIT

     15    0.7      18    0.7

 

21


     March 31, 2007    March 31, 2006

Dollars in Millions

   Net Sales    Months on
Hand
   Net Sales    Months on
Hand

ABILIFY* (total revenue)

   $ 293    0.4    $ 231    0.5

AVAPRO*/AVALIDE*

     163    0.4      139    0.4

BARACLUDE

     17    0.6      9    1.0

COUMADIN

     38    0.7      47    0.6

ERBITUX*

     158    0.3      136    —  

GLUCOPHAGE* Franchise

     21    0.6      25    0.7

KENALOG

     18    0.5      23    0.7

ORENCIA

     40    0.3      5    0.9

PARAPLATIN

     5    13.8      7    1.2

PLAVIX*

     787    0.6      850    0.4

PRAVACHOL

     57    0.6      302    0.4

REYATAZ

     143    0.7      119    0.6

SPRYCEL

     10    0.7      —      —  

SUSTIVA Franchise (a) (total revenue)

     144    0.7      108    0.5

ZERIT

     12    0.6      19    0.7

(a) Beginning in the third quarter of 2006, the SUSTIVA Franchise includes sales of SUSTIVA, as well as revenue of bulk efavirenz included in the combination therapy, ATRIPLA*. The estimated months on hand of the product in the U.S. wholesale distribution channel only include branded SUSTIVA inventory.

In October 2004, the U.S. pediatric exclusivity period for PARAPLATIN expired. The resulting entry of multiple generic competitors for PARAPLATIN led to a significant decrease in demand for PARAPLATIN, which in turn led to the months on hand of the product in the U.S. wholesaler distribution channel exceeding one month on hand at June 30, 2007, March 31, 2007, June 30, 2006 and March 31, 2006. The estimated value of PARAPLATIN inventory in the U.S. wholesaler distribution channel over one month on hand was approximately $0.3 million at June 30, 2007, $0.4 million at March 31, 2007, $1.4 million at June 30, 2006 and $0.9 million at March 31, 2006. The Company no longer produces PARAPLATIN for the U.S. market and will continue to monitor PARAPLATIN wholesaler inventory levels until they have been depleted.

For all products other than ERBITUX* and ORENCIA, the Company determines the above months on hand estimates by dividing the estimated amount of the product in the U.S. wholesaler distribution channel by the estimated amount of out-movement of the product from the U.S. wholesaler distribution channel over a period of 31 days, all calculated as described below. Factors that may influence the Company’s estimates include generic competition, seasonality of products, wholesaler purchases in light of increases in wholesaler list prices, new product launches, new warehouse openings by wholesalers and new customer stockings by wholesalers. In addition, such estimates are calculated using third-party data, which represent their own record-keeping processes and as such, may also reflect estimates.

The Company maintains inventory management agreements (IMAs) with most of its U.S. Pharmaceuticals wholesalers, which account for nearly 100% of total gross sales of U.S. pharmaceutical products. Under the current terms of the IMAs, the Company’s three largest wholesaler customers provide the Company with weekly information with respect to inventory levels of product on hand and the amount of out-movement of products. These three wholesalers accounted for 90% of total gross sales of U.S. Pharmaceuticals products in the second quarter of 2007. The inventory information received from these wholesalers excludes inventory held by intermediaries to whom they sell, such as retailers and hospitals, and excludes goods in transit to such wholesalers. The Company uses the information provided by these three wholesalers as of the Friday closest to quarter end to calculate the amount of inventory on hand for these wholesalers at the applicable quarter end. This amount is then increased by the Company’s estimate of goods in transit to these wholesalers based on the Company’s records of sales to these wholesalers, which have not been reflected in the weekly data provided by the wholesalers. Under the Company’s revenue recognition policy, sales are recorded when substantially all the risks and rewards of ownership are transferred, which in the U.S. Pharmaceuticals business is generally when product is shipped. In such cases, goods in transit to a wholesaler are owned by the applicable wholesaler and, accordingly, are reflected in the calculation of inventories in the wholesaler distribution channel. The Company determines the out-movement of a product from these wholesalers over a period of 31 days by using the most recent four weeks of out-movement of a product as provided by these wholesalers and extrapolating such amount to a 31 day basis.

 

22


The Company estimates for each product, inventory levels on hand and out-movements for all its U.S. Pharmaceuticals business wholesaler customers, by adjusting the three largest wholesalers’ inventory levels and out-movements by a factor that approximates the other remaining wholesalers’ percentage share of total gross sales for such product in the U.S. In addition, the Company receives inventory information from these other wholesalers on a selective basis for certain key products.

The Company’s U.S. Pharmaceuticals business through the IMAs discussed above, has arrangements with substantially all of its direct wholesaler customers and requires those wholesalers to maintain inventory at levels that are no more than one month of their demand.

ORENCIA was launched in February 2006. From launch through the second quarter of 2006, the Company distributed ORENCIA through an exclusive distribution arrangement with a single distributor. Following approval of the sBLA that allows a third party to manufacture ORENCIA at an additional site, the exclusive distribution arrangement terminated on July 17, 2006 and the Company expanded its distribution network for ORENCIA to multiple distributors. The above estimates of months on hand was calculated by dividing the inventories of ORENCIA held by these distributors at the end of the quarter by the out-movement of the product over the last 31 day period, as reported by these distributors. The inventory on hand and out-movements reported by these distributors are a product of the distributors’ own record-keeping processes.

In the first and second quarter of 2006, the Company sold ERBITUX* to intermediaries (such as wholesalers and specialty oncology distributors) and shipped ERBITUX* directly to the end-users of the product who are the customers of those intermediaries. Beginning in the third quarter of 2006, the Company expanded its distribution model to include two distributors who then held ERBITUX* inventory. One additional distributor was added for ERBITUX* in the first quarter of 2007.

The above estimate of months on hand was calculated by dividing the inventories of ERBITUX* held by the distributors for their own accounts as reported by the distributors as of the end of the quarter by the out-movements of the product reported by the distributors over the last 31 day period. The inventory levels reported by the distributors are a product of their record-keeping process.

 

23


International Pharmaceuticals, Nutritionals and Other Health Care

The following table sets forth for each of the Company’s key pharmaceutical products and other growth drivers sold by the Company’s International Pharmaceuticals reporting segment, including the top 15 pharmaceutical products sold in the Company’s major non-U.S. countries (based on 2006 net sales), and for each of the key products sold by the other reporting segments listed below, the percentage change in the Company’s estimated ultimate patient/consumer demand for the months of March 2007 and December 2006 compared to the same period in the prior year.

 

     % Change in Demand on a Constant U.S. Dollar Basis  
    

June 2007

vs. June 2006

   

March 2007

vs. March 2006

 

International Pharmaceuticals

    

ABILIFY* (total revenue)

   45     33  

AVAPRO*/AVALIDE*

   0     5  

BARACLUDE

   * *   * *

BUFFERIN*

   (8 )   (8 )

CAPOTEN

   (21 )   (16 )

DAFALGAN

   39     12  

EFFERALGAN

   29     16  

MAXIPIME

   (18 )   (24 )

MONOPRIL

   (25 )   (13 )

ORENCIA

   * *   * *

PERFALGAN

   31     15  

PLAVIX*

   0     (2 )

PRAVACHOL

   (64 )   (73 )

REYATAZ

   5     24  

SPRYCEL

   N/A     N/A  

SUSTIVA Franchise (total revenue)

   (1 )   9  

TAXOL® (paclitaxel)

   (29 )   (24 )

VIDEX/VIDEX EC

   (9 )   (2 )

Nutritionals

    

ENFAMIL/ENFAGROW

   4     5  

NUTRAMIGEN

   (3 )   4  

Other Health Care

    

ConvaTec

    

Ostomy

   2     0  

Wound Therapeutics

   3     (2 )

Medical Imaging

    

CARDIOLITE

   (2 )   (8 )

** In excess of 200%

 

24


Estimated Inventory Months on Hand in the Distribution Channel

The following table sets forth for each of the Company’s key products sold by the reporting segments listed below, the net sales of the applicable product for each of the quarters ended June 30, 2007, March 31, 2007, June 30, 2006, and March 31, 2006, and the estimated number of months on hand of the applicable product in the direct customer distribution channel for the reporting segment as of the end of each of the four quarters. The estimates of months on hand for key products described below for the International Pharmaceuticals reporting segment are based on data collected for all of the Company’s significant business units outside of the U.S. Also described further below is information on non-key product(s) where the amount of inventory on hand at direct customers is more than approximately one month and the impact is not de minimis. For the other reporting segments, estimates are based on data collected for the U.S. and all significant business units outside of the U.S.

 

     June 30, 2007    March 31, 2007

Dollars in Millions

   Net Sales   

Months

On Hand

   Net Sales   

Months

On Hand

International Pharmaceuticals

           

ABILIFY* (total revenue)

   $ 90    0.6    $ 73    0.6

AVAPRO*/AVALIDE*

     127    0.5      107    0.5

BARACLUDE

     39    0.7      28    0.7

BUFFERIN*

     27    0.5      24    0.5

CAPOTEN

     25    0.9      26    0.8

DAFALGAN

     42    1.4      44    1.2

EFFERALGAN

     69    1.4      81    1.1

MAXIPIME

     39    0.8      29    0.5

MONOPRIL

     42    1.2      36    0.8

ORENCIA

     2    0.4      1    0.3

PERFALGAN

     65    0.5      58    0.5

PLAVIX*

     174    0.6      151    0.5

PRAVACHOL

     85    0.6      78    0.6

REYATAZ

     116    0.7      120    0.9

SPRYCEL

     21    0.4      11    0.4

SUSTIVA Franchise (a) (total revenue)

     86    0.5      82    0.5

TAXOL® (paclitaxel)

     91    0.6      107    0.7

VIDEX/VIDEX EC

     27    1.1      27    1.1

Nutritionals

           

ENFAMIL/ENFAGROW

     337    0.9      326    0.8

NUTRAMIGEN

     54    1.0      52    0.9

Other Health Care

           

ConvaTec

           

Ostomy

     150    0.9      130    0.9

Wound Therapeutics

     119    0.9      107    0.9

Medical Imaging

           

CARDIOLITE

     106    0.7      99    0.7

(a) Beginning in the third quarter of 2006, the SUSTIVA Franchise includes sales of SUSTIVA, as well as revenue of bulk efavirenz included in the combination therapy, ATRIPLA*. The estimated months on hand of the product in the distribution channel only include branded SUSTIVA inventory.

 

25


     June 30, 2006    March 31, 2006

Dollars in Millions

   Net Sales   

Months

on Hand

   Net Sales   

Months

on Hand

International Pharmaceuticals

           

ABILIFY* (total revenue)

   $ 57    0.6    $ 52    0.6

AVAPRO*/AVALIDE*

     113    0.5      94    0.5

BARACLUDE

     5    1.0      2    1.1

BUFFERIN*

     31    0.5      22    0.6

CAPOTEN

     31    0.9      35    0.8

DAFALGAN

     37    1.1      37    1.4

EFFERALGAN

     62    0.9      68    1.2

MAXIPIME

     43    0.8      40    0.8

MONOPRIL

     48    1.1      46    1.1

ORENCIA

     —      —        —      —  

PERFALGAN

     51    0.6      46    0.6

PLAVIX*

     157    0.5      136    0.5

PRAVACHOL

     195    1.4      234    1.5

REYATAZ

     114    0.7      88    0.6

SPRYCEL

     —      —        —      —  

SUSTIVA

     78    0.5      67    0.5

TAXOL® (paclitaxel)

     145    0.5      143    0.6

VIDEX/VIDEX EC

     35    1.2      31    0.8

Nutritionals

           

ENFAMIL/ENFAGROW

     312    0.9      304    0.9

NUTRAMIGEN

     54    1.0      48    1.0

Other Health Care

           

ConvaTec

           

Ostomy

     141    1.0      123    0.9

Wound Therapeutics

     107    0.9      98    0.9

Medical Imaging

           

CARDIOLITE

     105    0.8      103    0.8

The above months on hand information represents the Company’s estimates of aggregate product level inventory on hand at direct customers divided by the expected demand for the applicable product. Expected demand is the estimated ultimate patient/consumer demand calculated based on estimated end-user consumption or direct customer out-movement data over the most recent 31 day period or other reasonable period. Factors that may affect the Company’s estimates include generic competition, seasonality of products, direct customer purchases in light of price increases, new product or product presentation launches, new warehouse openings by direct customers, new customer stockings by direct customers and expected direct customer purchases for governmental bidding situations.

The Company relies on a variety of methods to calculate months on hand for these reporting segments. Where available, the Company relies on information provided by third parties to determine estimates of aggregate product level inventory on hand at direct customers and expected demand. For the reporting segments listed above; however, the Company has limited information on direct customer product level inventory, end-user consumption and direct customer out-movement data. Further, the quality of third-party information, where available, varies widely. In some circumstances, such as the case with new products or seasonal products, such historical end-user consumption or out-movement information may not be available or applicable. In such cases, the Company uses estimated prospective demand. In cases where direct customer product level inventory, ultimate patient/consumer demand or out-movement data do not exist or are otherwise not available, the Company has developed a variety of other methodologies to calculate estimates of such data, including using such factors as historical sales made to direct customers and third-party market research data related to prescription trends and end-user demand.

 

26


As of March 31, 2006, BARACLUDE, an antiviral product, had approximately 1.1 months of inventory on hand at direct customers. The level of inventory on hand is due primarily to stocking of the product in support of the launch in China.

As of June 30, 2007, March 31, 2007, June 30, 2006, and March 31, 2006, DAFALGAN, an analgesic product sold principally in Europe, had approximately 1.4 months, 1.2 months, 1.1 months and 1.4 months of inventory on hand, respectively, at direct customers. The level of inventory on hand is due primarily to private pharmacists purchasing DAFALGAN approximately once every eight weeks and the seasonality of the product.

As of June 30, 2007, March 31, 2007, and March 31, 2006, EFFERALGAN, an analgesic product sold principally in Europe, had approximately 1.4 months, 1.1 months and 1.2 months of inventory on hand, respectively, at direct customers. The level of inventory on hand is due primarily to private pharmacists purchasing EFFERALGAN approximately once every eight weeks and the seasonality of the product.

As of June 30, 2007, June 30, 2006 and March 31, 2006, MONOPRIL, a cardiovascular product, had approximately 1.2 months, 1.1 months and 1.1 months of inventory on hand, respectively, at direct customers. The level of inventory on hand as of June 30, 2007, is due primarily to initial stocking of a new, exclusive distributor in Poland and stocking in support of the launch of MONOPRIL in Poland in 2007. The level of inventory on hand as of June 30, 2006 and March 31, 2006, was due primarily to supply of the product in support of its inclusion in a government program in Russia.

As of June 30, 2006 and March 31, 2006, PRAVACHOL, a cardiovascular product, had approximately 1.4 months and 1.5 months of inventory on hand, respectively, at direct customers. The increased level of inventory on hand was due primarily to an increase in orders from a significant direct customer in France.

As of June 30, 2007, March 31, 2007 and June 30, 2006, VIDEX/VIDEX EC, an antiviral product, had approximately 1.1 months, 1.1 months, and 1.2 months of inventory on hand at direct customers. The increased level of inventory on hand is due primarily to government purchasing patterns in Brazil. The Company is contractually obligated to provide VIDEX/VIDEX EC to the Brazilian government upon placement of an order for product by the government. Under the terms of the contract, the Company has no control over the inventory levels relating to such orders.

The Company continuously seeks to improve the quality of its estimates of months on hand of inventories held by its direct customers including thorough review of its methodologies and processes for calculation of these estimates and review and analysis of its own and third parties’ data used in such calculations. The Company expects that it will continue to review and refine its methodologies and processes for calculation of these estimates and will continue to review and analyze its own and third parties’ data in such calculations.

 

27

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