-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, DSI/G5IybGMVZLWblFIqDg2BOwmOBE5XqdFLtmb0udjBUpvIH4i+TbvwMUyF3sOO u+upIgolGitGdbp+YRuDWw== 0001193125-07-012503.txt : 20070125 0001193125-07-012503.hdr.sgml : 20070125 20070125100441 ACCESSION NUMBER: 0001193125-07-012503 CONFORMED SUBMISSION TYPE: 8-K PUBLIC DOCUMENT COUNT: 4 CONFORMED PERIOD OF REPORT: 20070125 ITEM INFORMATION: Results of Operations and Financial Condition ITEM INFORMATION: Financial Statements and Exhibits FILED AS OF DATE: 20070125 DATE AS OF CHANGE: 20070125 FILER: COMPANY DATA: COMPANY CONFORMED NAME: BRISTOL MYERS SQUIBB CO CENTRAL INDEX KEY: 0000014272 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 220790350 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 8-K SEC ACT: 1934 Act SEC FILE NUMBER: 001-01136 FILM NUMBER: 07551472 BUSINESS ADDRESS: STREET 1: 345 PARK AVE CITY: NEW YORK STATE: NY ZIP: 10154 BUSINESS PHONE: 2125464000 MAIL ADDRESS: STREET 1: 345 PARK AVE CITY: NEW YORK STATE: NY ZIP: 10154 FORMER COMPANY: FORMER CONFORMED NAME: BRISTOL MYERS CO DATE OF NAME CHANGE: 19891012 8-K 1 d8k.htm FORM 8-K Form 8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 


FORM 8-K

 


CURRENT REPORT

Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): January 25, 2007

 


BRISTOL-MYERS SQUIBB COMPANY

(Exact Name of Registrant as Specified in its Charter)

 


 

Delaware   1-1136   22-079-0350

(State or Other Jurisdiction of

Incorporation)

  (Commission File Number)  

(IRS Employer

Identification Number)

345 Park Avenue

New York, NY, 10154

(Address of Principal Executive Office)

Registrant’s telephone number, including area code: (212) 546-4000

 


Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

¨ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 



Item 2.02. Results of Operations and Financial Condition.

On January 25, 2007, Bristol-Myers Squibb Company (the “Company”) issued a press release reporting its financial results for the fourth quarter and twelve months of 2006 and announcing 2007 earnings guidance. A copy of the press release is furnished as Exhibit 99.1 to this report and incorporated herein by reference. Also furnished and incorporated by reference as Exhibit 99.2 is certain supplemental information posted on the Company’s website at www.bms.com.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.

 

99.1    Press release of Bristol-Myers Squibb Company dated January 25, 2007
99.2    Certain supplemental information posted on Bristol-Myers Squibb Company’s website at www.bms.com not included in the press release


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

Dated: January 25, 2007  

BRISTOL-MYERS SQUIBB COMPANY

 

By:

 

/s/ Sandra Leung

  Name:   Sandra Leung
  Title:   Secretary


EXHIBIT INDEX

 

Exhibit No.  

Description

99.1   Press release of Bristol-Myers Squibb Company dated January 25, 2007
99.2   Certain supplemental information posted on Bristol-Myers Squibb Company’s website at www.bms.com not included in the press release
EX-99.1 2 dex991.htm PRESS RELEASE OF BRISTOL-MYERS SQUIBB COMPANY DATED JANUARY 25, 2007 Press release of Bristol-Myers Squibb Company dated January 25, 2007

Exhibit 99.1

LOGO

 

Contact:    Media    Investors
   Tony Plohoros    John Elicker
   Communications    Investor Relations
   212-546-4379    212-546-3775
   tony.plohoros@bms.com    john.elicker@bms.com
   Jeff Macdonald    Blaine Davis
   Communications    Investor Relations
   212-546-4824    212-546-4631
   jeffrey.macdonald@bms.com    blaine.davis@bms.com

BRISTOL-MYERS SQUIBB COMPANY REPORTS FINANCIAL RESULTS FOR THE

FOURTH QUARTER AND TWELVE MONTHS OF 2006 AND ANNOUNCES EPS GUIDANCE FOR 2007

 

    Posts Fourth Quarter 2006 GAAP Loss Per Share of $0.07 Impacted by Previously Announced Specified Items and Records Full Year 2006 GAAP EPS of $0.81

 

    Posts Fourth Quarter 2006 Non-GAAP EPS of $0.19 and Records Full Year 2006 Non-GAAP EPS of $1.09

 

    Announces Full Year 2007 GAAP EPS Guidance at $1.12 to $1.22

 

    Announces Full Year 2007 Non-GAAP Guidance at $1.20 to $1.30

(NEW YORK, January 25, 2007) – Bristol-Myers Squibb Company (NYSE:BMY) today reported financial results for the fourth quarter and twelve months ended December 31, 2006 and announced 2007 earnings guidance.

Bristol-Myers Squibb posted fourth quarter 2006 net sales from continuing operations of $4.2 billion, compared with $5.0 billion for the same period in 2005. The company reported a fourth quarter 2006 net loss from continuing operations of $134 million, or a loss of $0.07 per diluted share, under U.S. Generally Accepted Accounting Principles (GAAP), compared to net earnings of $499 million, or $0.26 per diluted share for the same period in 2005. The net loss was driven by an increase in litigation reserves and early debt retirement costs. On a non-GAAP basis excluding specified items, fourth quarter 2006 net earnings from continuing operations were $380 million, or $0.19 per diluted share, compared to $601 million, or $0.31 per diluted share for the same period in 2005. The decrease in


non-GAAP net earnings in 2006 as compared to 2005 is mainly due to the impact of the at-risk launch of generic clopidogrel bisulfate in August 2006, which continued to have a significant adverse effect in the fourth quarter, and the loss of patent exclusivity on PRAVACHOL® in major markets.

“The company remains focused on executing our strategy and building shareholder value, with an expected return to sales and earnings growth beginning this year,” said Jim Cornelius, chief executive officer, Bristol-Myers Squibb. “Our ongoing commitment to increasing investment in R&D has yielded a robust late-stage pipeline, demand for our major products continues to increase at a double-digit rate, and PLAVIX® market share is increasing as remaining generic inventory depletes.”

For the twelve months ended December 31, 2006, net sales from continuing operations decreased 7% to $17.9 billion compared with net sales of $19.2 billion for the same period in 2005. Net earnings from continuing operations for the full year 2006 on a GAAP basis were $1.6 billion, or $0.81 per diluted share, compared to $3.0 billion, or $1.52 per diluted share for the same period last year. On a non-GAAP basis excluding specified items, Bristol-Myers Squibb reported net earnings from continuing operations for the full year 2006 of $2.1 billion, or $1.09 per diluted share, compared to $2.8 billion, or $1.43 per diluted share for the same period last year.

NEW PRODUCT AND PIPELINE DEVELOPMENTS

On January 11, Bristol-Myers Squibb and AstraZeneca PLC (AstraZeneca) announced a collaboration to develop and commercialize two investigational compounds, saxagliptin and dapagliflozin, being studied for the treatment of Type 2 diabetes. Both compounds were discovered by Bristol-Myers Squibb. The collaboration on these compounds is worldwide, except for Japan. Terms of the agreements include an upfront payment of $100 million by AstraZeneca to Bristol-Myers Squibb, as well as additional payments of up to $650 million based on development and regulatory milestones for the two compounds and potential sales milestones up to $300 million per product. Additionally, the companies have agreed upon initial development plans for the two compounds, with AstraZeneca funding the majority of development costs from 2007 through 2009. Separately, the company also announced a collaboration with Otsuka Pharmaceutical Co., Ltd. to develop saxagliptin in Japan.

On January 10, Bristol-Myers Squibb and ImClone Systems Incorporated announced that data from a pivotal Phase III study of ERBITUX® plus FOLFIRI (an irinotecan-based chemotherapy) met the primary endpoint of increasing median duration of progression-free survival over FOLFIRI alone in patients with previously untreated metastatic colorectal cancer (mCRC).

 

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In November 2006, the U.S. Food and Drug Administration (FDA) granted Fast Track designation for ipilimumab used as combination with chemotherapy (dacarbazine) in previously untreated metastatic melanoma patients. The FDA also granted Fast Track designation for ipilimumab used as a monotherapy in previously treated metastatic melanoma patients. The company is working toward a potential submission date of late 2007.

In November 2006, the company received European Medicine Evaluation Agency (EMEA) approval of SPRYCEL (dasatinib) for the treatment of adults with chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia (CML) or Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) with resistance or intolerance to prior therapy, including GLEEVEC® (imatinib mesylate). SPRYCEL was launched in the U.S. and certain European markets during 2006.

FOURTH QUARTER RESULTS

 

  Fourth quarter 2006 net sales from continuing operations decreased 16% to $4.2 billion compared to the same period in 2005. U.S. net sales decreased 26% to $2.1 billion for the quarter compared to 2005, while international net sales decreased 3%, including a 4% favorable foreign exchange impact, to $2.1 billion.

 

  Cost of products sold, as a percentage of net sales, increased to 34.3% in the fourth quarter of 2006 compared to 31.8% in 2005 in the same period. This increase was primarily due to the unfavorable impact of pharmaceutical net sales mix, including lower sales of PLAVIX® as well as a reclassification of certain costs from marketing, selling and administrative expenses to cost of products sold.

 

  Marketing, selling and administrative expenses decreased by 4% to $1.3 billion in the fourth quarter of 2006 compared to the same period in 2005, mainly due to the reclassification of certain costs from marketing, selling and administrative expenses to cost of products sold as noted above; lower sales force expenses resulting from the previously announced restructuring of the U.S. primary care sales organization that became effective in March 2006; and lower expenses for PRAVACHOL®.

 

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  Advertising and product promotion spending decreased by 6% to $418 million in the fourth quarter of 2006 from $444 million in the same period in 2005, primarily driven by lower spending across various brands, partially offset by increased investments in new products.

 

  Research and development expenses increased by 6% to $821 million in the fourth quarter of 2006 from $775 million in the same period in 2005, principally reflecting continued investments in late-stage compounds and higher licensing milestone payments.

 

  In the fourth quarter of 2006, the company recorded pre-tax charges of $22 million related to the adoption of a new accounting standard for stock option expensing that became effective on January 1, 2006. The charges were recorded in cost of products sold, marketing, selling and administrative expenses, and research and development expenses.

INCOME TAXES

The effective income tax rate on loss from continuing operations before minority interest and income taxes was a benefit of 58.6% for the three months ended December 31, 2006, compared with an effective tax rate of 21.4% for the earnings from continuing operations before minority interest and income taxes for the three months ended December 31, 2005. The fourth quarter 2006 tax benefit was in part attributable to the reinstatement of the U. S. Federal Research and Development credit in December 2006, which was partially offset by the treatment of provisions for a portion of certain litigation reserves as non-deductible.

SPECIFIED ITEMS

In the three months ended December 31, 2006 and 2005, the company recorded specified income and expense items that affected the comparability of the results.

The pre-tax specified items in 2006 included:

 

    $353 million charge for an increase in reserves for the settlement in principle of pricing and sales investigations, a $13 million charge related to a claim for damages and $7 million of income from insurance recovery from an unrelated matter
    $220 million net charge primarily associated with early debt retirement costs in connection with the repurchase of the company’s $2.5 billion Notes due 2011

 

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    $96 million charge related to asset impairment, accelerated depreciation, and downsizing and streamlining of worldwide operations
    $35 million charge for milestone payments

The pre-tax specified items in 2005 included:

 

    $197 million charge for increase in litigation reserves
    $86 million charge related to asset impairment, accelerated depreciation, and downsizing and streamlining of worldwide operations
    $9 million charge primarily related to milestone payments
    $138 million deferred income recognized, net of other costs, resulting from the company’s termination of its collaborative agreement with Merck, Inc. for muraglitazar

For additional information on specified items, see “Use of Non-GAAP Financial Information” and Appendix 1. Details reconciling these non-GAAP amounts with GAAP amounts including specified items are provided in supplemental materials available on the company’s website.

PHARMACEUTICALS

Worldwide pharmaceutical sales decreased 22%, including a 2% favorable foreign exchange impact, to $3.1 billion in the fourth quarter of 2006 compared to the same period in 2005. Worldwide sales of the products that the company views as growth drivers* decreased by 15% in the fourth quarter of 2006 as compared to the same period in 2005. Excluding PLAVIX®, worldwide sales of the other growth drivers* increased 35% in the fourth quarter of 2006 as compared to the same period in 2005.

U.S. pharmaceutical sales decreased 32% to $1.5 billion in the fourth quarter of 2006 compared to the same period in 2005, primarily due to lower sales of PLAVIX® and the loss of exclusivity of PRAVACHOL® primarily offset by continued growth of ABILIFY®, ERBITUX®, the SUSTIVA® franchise, REYATAZ® and AVAPRO®/AVALIDE® and sales of new products ORENCIA®, BARACLUDE® and SPRYCEL. In aggregate, estimated U.S. wholesaler inventory levels of the company’s key pharmaceutical products sold by the U.S. Pharmaceutical business at the end of the fourth quarter decreased to less than three weeks.

International pharmaceutical sales decreased 8%, including a 4% favorable foreign exchange impact, to $1.6 billion for the fourth quarter of 2006 compared to the same period in 2005. The decrease was mainly due to a decline in PRAVACHOL® and TAXOL® sales resulting from increased generic

 

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competition in Europe, partially offset by increased sales of newer products including REYATAZ®, ABILIFY® and BARACLUDE®. The company’s reported international sales do not include copromotion sales reported by its alliance partner, sanofi-aventis, for PLAVIX® and AVAPRO®/AVALIDE®, which continued to show growth in the fourth quarter of 2006.

Product Sales

 

  Sales of PLAVIX®, a platelet aggregation inhibitor that is part of the company’s alliance with sanofi-aventis, decreased 53%, including a 1% favorable foreign exchange impact, to $496 million in the fourth quarter of 2006 from $1,061 million in the same period in 2005. Sales of PLAVIX® decreased 62% in the U.S. in the fourth quarter of 2006 to $343 million from $906 million in the same period in 2005. The at-risk launch of generic clopidogrel bisulfate continued to have a significant adverse effect on sales in the fourth quarter, which the company estimates to be in the range of $700 million to $750 million. Estimated total U.S. prescription demand for clopidogrel bisulfate (branded and generic) increased by 14% in the fourth quarter of 2006 compared to 2005, while estimated total U.S. prescription demand for branded PLAVIX® decreased by 64% in the same period. Estimated U.S. wholesaler inventory levels for PLAVIX® decreased to approximately two and a half weeks at December 31, 2006 as a result of an inventory workdown during the fourth quarter. The full impact of the Apotex Corp. and Apotex Inc. (Apotex) launch of its generic clopidogrel bisulfate product on the company cannot be estimated with certainty at this time and will depend on a number of factors, including the amount of generic product Apotex sold into the distribution channels in August 2006 before the preliminary injunction was granted halting further sales, the extent to which the launch by Apotex will permanently adversely impact the pricing for PLAVIX® and the impact on prescription demand for clopidogrel bisulfate had Apotex not launched the generic product at risk.

 

  Sales of AVAPRO®/AVALIDE®, an angiotensin II receptor blocker for the treatment of hypertension that is also part of the sanofi-aventis alliance, increased 11%, including a 2% favorable foreign exchange impact, to $307 million in the fourth quarter of 2006 from $277 million in the same period in 2005. U.S. sales increased 8% to $182 million in the fourth quarter of 2006 from $168 million in the same period in 2005, primarily due to higher demand and higher average net selling prices. Estimated total U.S. prescription demand increased approximately 2% compared to 2005. International sales increased 15%, including a 5% favorable foreign exchange impact, to $125 million compared to $109 million in the same period in 2005.

 

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  Total revenue for ABILIFY®, an antipsychotic agent for the treatment of schizophrenia, acute bipolar mania and bipolar disorder, increased 62%, including a 2% favorable foreign exchange impact, to $362 million in the fourth quarter of 2006 from $224 million in the same period in 2005. U.S. sales increased 68% to $294 million in the fourth quarter 2006 from $175 million in the same period in 2005, primarily due to higher demand, higher average net selling prices and a benefit resulting from a reduction in U.S. wholesaler inventory in 2005. Estimated total U.S. prescription demand increased approximately 17% compared to the same period last year. International sales of ABILIFY® have begun to gain momentum, increasing 39% in the fourth quarter of 2006 to $68 million. Total revenue for ABILIFY® primarily consists of alliance revenue representing the company’s 65% share of net sales in countries where it copromotes with Otsuka Pharmaceutical Co., Ltd.

 

  Sales of REYATAZ®, a protease inhibitor for the treatment of HIV, increased 36%, including a 3% favorable foreign exchange impact, to $255 million in the fourth quarter of 2006 from $188 million in the same period in 2005, primarily due to increased demand in the U.S., Europe and Latin America. U.S. sales increased 31% to $144 million in the fourth quarter of 2006 from $110 million in the same period in 2005, primarily due to higher demand and higher average net selling prices. Estimated total U.S. prescription demand increased approximately 20% compared to 2005. International sales increased 42%, including a 8% favorable foreign exchange impact, to $111 million in the fourth quarter of 2006 from $78 million in the same period in 2005.

 

  Sales of ERBITUX®, which is sold by the company almost exclusively in the U.S., increased 38% to $167 million in the fourth quarter of 2006 from $121 million in the same period in 2005, driven by increased demand for usage in the treatment of both head and neck cancer and colorectal cancer. ERBITUX® is marketed by the company under a distribution and copromotion agreement with ImClone Systems Incorporated.

 

  Sales for BARACLUDE®, ORENCIA® and SPRYCEL were $36 million, $32 million and $14 million, respectively, in the fourth quarter of 2006. These recently launched products continue to gain market share.

 

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  Total revenue for the SUSTIVA® franchise, a non-nucleoside reverse transcriptase inhibitor for the treatment of HIV, increased 31%, including a 3% favorable foreign exchange impact, to $222 million in the fourth quarter of 2006 from $170 million in the same period in 2005. Estimated total U.S. prescription demand for the SUSTIVA® franchise increased approximately 21% compared to 2005. Total revenue for the SUSTIVA® franchise includes sales of SUSTIVA® as well as revenue from bulk efavirenz included in the combination therapy ATRIPLATM, which is sold through a joint venture with Gilead Sciences, Inc.

 

  Sales of PRAVACHOL®, an HMG Co-A reductase inhibitor, decreased 75%, including a 1% favorable foreign exchange impact, to $146 million in the fourth quarter of 2006 from $584 million in the same period in 2005, due to loss of market exclusivity resulting in generic competition for most strengths in the U.S. beginning in April 2006, and generic competition in key European markets, including France, beginning in July 2006.

 

  Sales of TAXOL®, an anti-cancer agent sold almost exclusively in non-U.S. markets, decreased 28%, including a 1% favorable foreign exchange impact, to $130 million in the fourth quarter of 2006 from $181 million in the same period in 2005, primarily due to increased generic competition in Europe and generic entry in Japan during the third quarter of 2006.

HEALTH CARE GROUP

The combined fourth quarter 2006 revenues from the Health Care Group increased 6% to $1.1 billion compared to the same period in 2005.

Nutritionals

Worldwide Nutritional sales increased 6%, including a 2% favorable foreign exchange impact, to $618 million in the fourth quarter of 2006 from $584 million in the same period in 2005. U.S. Nutritional sales increased 5% to $295 million in the fourth quarter of 2006, primarily due to increased sales of ENFAMIL®, the company’s best selling infant formula. International Nutritional sales increased 7% to $323 million in the fourth quarter of 2006, including a 4% favorable foreign exchange impact, primarily due to increased sales of ENFAGROW®.

 

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Other Health Care

 

  Worldwide ConvaTec sales increased 9%, including a 5% favorable foreign exchange impact, to $291 million in the fourth quarter of 2006 from $267 million in the same period in 2005. Sales of wound therapeutic products increased 10%, including a 5% favorable foreign exchange impact, to $123 million in the fourth quarter of 2006 from $112 million in the same period in 2005, primarily due to continued growth of the AQUACEL® franchise.

 

  Worldwide Medical Imaging sales remained relatively flat at $156 million in the fourth quarter of 2006 as compared to the same period in 2005. CARDIOLITE® sales increased 3% from the same period in 2005.

2007 GUIDANCE

Bristol-Myers Squibb estimates its 2007 fully-diluted earnings guidance for fully-diluted earnings per share from continuing operations on a GAAP basis to be between $1.12 and $1.22.

The company also estimates its 2007 fully-diluted earnings per share guidance to be between $1.20 and $1.30 on a non-GAAP basis, which excludes specified items as discussed under “Use of Non-GAAP Financial Information.” Details reconciling adjusted non-GAAP amounts with the amounts reflecting specified items are provided in supplemental materials available on the company’s website.

The company expects generic clopidogrel bisulfate that was sold into distribution channels following the Apotex at-risk launch in August 2006 will have a residual impact on PLAVIX® net sales and the company’s overall financial results into 2007; the amount and duration of which will depend on the amount of generic product Apotex sold into the distribution channels. The company’s 2007 guidance range assumes that up to six months of total generic inventory was sold into the distribution channels in August 2006 before the preliminary injunction was granted halting further sales. PLAVIX® net sales are expected to increase over time as generic inventory in the distribution channels is depleted.

For 2007, the company expects reductions of net sales for products that have lost exclusivity in previous years to moderate to a range between $900 million and $1.0 billion, as compared to $1.4

 

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billion in 2006, and $1.3 billion in 2005. While the company expects generic clopidogrel bisulfate inventory in the market to have a continued residual impact on 2007 PLAVIX® net sales, the company does expect PLAVIX® net sales and earnings growth in 2007, assuming the absence of renewed or additional generic competition. The company expects increased prescription demand for PLAVIX® as well as for other key brands and newly launched products. Compared to 2006, the gross margin is expected to improve due to net sales growth of higher margin products, lower margin erosion related to exclusivity losses, and manufacturing efficiencies. Marketing, selling and administrative expense is expected to remain relatively unchanged as the company continues to focus on high value primary care and specialist physicians and implements various productivity initiatives. The company expects to continue to increase investments to develop additional new compounds and support the introduction of new products.

The company and its subsidiaries are the subject of a number of significant pending lawsuits, claims, proceedings and investigations in addition to the pending PLAVIX® litigation, described below. It is not possible at this time reasonably to assess the final outcome of these investigations or litigations. Management continues to believe, as previously disclosed, that the aggregate impact, beyond current reserves, of the pending PLAVIX® patent litigation, these other litigations and investigations and other legal matters affecting the company is reasonably likely to be material to the company’s results of operations and cash flows, and may be material to its financial condition and liquidity. The company’s GAAP and non-GAAP guidance for 2007 described above does not reflect the potential impact of either the pending PLAVIX® patent litigation as described below or the impact of any other legal matters on the company’s results of operations for 2007, beyond current reserves for ongoing matters.

As previously disclosed, the composition of matter patent for PLAVIX®, which expires in 2011, is subject to litigation in the U.S. with Apotex. The trial in the patent litigation began on January 22, 2007. If Apotex were to prevail in the trial in the patent litigation, the company would expect to face renewed generic competition for PLAVIX® promptly thereafter. There are other pending PLAVIX® patent litigations in the United States and in other less significant markets for the product. The company continues to believe that the PLAVIX® patents are valid and infringed, and with sanofi-aventis, is vigorously pursuing these cases.

 

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It is not possible at this time reasonably to assess the ultimate outcome of the patent litigation with Apotex or of the other PLAVIX® patent litigations, or the timing of any renewed generic competition for PLAVIX® from Apotex or additional generic competition for PLAVIX® from other generic pharmaceutical companies. Loss of market exclusivity of PLAVIX® and/or the development of sustained generic competition would be material to the company’s sales of PLAVIX®, results of operations and cash flows, and could be material to the company’s financial condition and liquidity. PLAVIX® is the company’s largest product by net sales, and U.S. net sales for PLAVIX® were $2.7 billion and $3.2 billion in 2006 and 2005, respectively.

As previously disclosed, the Antitrust Division of the United States Department of Justice is conducting a criminal investigation regarding the proposed settlement of the pending PLAVIX® patent litigation with Apotex. The company is cooperating fully with the investigation. It is not possible at this time reasonably to assess the outcome of the investigation or its impact on the company. It is also not possible at this time reasonably to assess the impact of the investigation, if any, on the company’s compliance with the Deferred Prosecution Agreement (DPA) with the United States Attorney’s Office for the District of New Jersey (USAO). Also as previously disclosed, the USAO initiated an investigation that is being conducted by the Monitor and the USAO into the company’s negotiations of the proposed settlement with Apotex. This investigation includes a review of corporate governance issues and whether there was any violation of Federal securities laws in connection with the proposed settlement with Apotex under the terms of the previously disclosed Consent Order the company entered into with the U.S. Securities and Exchange Commission in August 2004 (SEC Consent). It is not possible at this time reasonably to assess the outcome of the investigation or its impact on the company.

As previously disclosed, in December 2006, the company, the United States Department of Justice (DOJ), and the Office of the United States Attorney for the District of Massachusetts have reached an agreement in principle, subject to approval by the DOJ, to settle several investigations involving the company’s drug pricing, and sales and marketing activities. The agreement in principle provides for a civil resolution and an expected payment of $499 million. There would be no criminal charges against the company. The agreement in principle also provides for the company to enter into a corporate integrity agreement with the Office of Inspector General of the U.S. Department of Health and Human Services. The settlement is contingent upon the parties’ agreement to the terms of a final settlement agreement, including on the terms of the corporate integrity agreement, and approval by the DOJ. There can be no assurance that the settlement will be

 

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finalized. As a result of the agreement in principle, the company in the fourth quarter of 2006 increased its reserves related to these investigations by $353 million, bringing the aggregate reserves for these matters to $499 million.

For additional discussion of legal matters, including the PLAVIX® patent litigation, the Antitrust Division investigation related to the proposed settlement with Apotex and the terms of the DPA and SEC Consent, see “Item 1. Financial Statements Note 18. Legal Proceedings and Contingencies,” and “Management’s Discussion and Analysis – SEC Consent Order and Deferred Prosecution Agreement” in the company’s Form 10-Q Quarterly Report for the period ended September 30, 2006.

Use of Non-GAAP Financial Information

This press release contains non-GAAP earnings and earnings per share information adjusted to exclude certain costs, expenses, gains and losses and other specified items. Among the items in GAAP earnings but excluded for purposes of determining adjusted earnings are: gains or losses from sale of businesses and product lines; from sale or write-down of equity investments and from discontinuations of operations; restructuring items that meet the requirements of SFAS 112 for severance and SFAS 146 for other exit costs; accelerated depreciation charges under SFAS 144 related to restructuring items described above; asset impairments; charges and recoveries relating to significant legal proceedings; upfront and milestone payments for in-licensing of products that have not achieved regulatory approval that are immediately expensed; copromotion or alliance charges and payments for in-process research and development which under GAAP are immediately expensed rather than amortized over the life of the agreement; income from upfront and milestone payments that is immediately recognized for out-licensing of products, including deferred income recognized upon termination; costs of early debt retirement; and significant tax events, including the repatriation of special dividends pursuant to the American Jobs Creation Act of 2004. This information is intended to enhance an investor’s overall understanding of the company’s past financial performance and prospects for the future. For example, non-GAAP earnings per share information is an indication of the company’s baseline performance before items that are considered by the company not to be reflective of the company’s ongoing results. In addition, this information is among the primary indicators the company uses as a basis for evaluating company performance, allocating resources, setting incentive compensation targets, and planning and forecasting of future periods. This information is not intended to be considered in isolation or as a substitute for diluted earnings per share prepared in accordance with GAAP.

Statement on Cautionary Factors

This press release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 regarding, among other things, statements relating to goals, plans and projections regarding the company’s financial position, results of operations, market position, product development and business strategy. These statements may be identified by the fact that they use words such as “anticipate”, “estimates”, “should”, “expect”, “guidance”, “project”, “intend”, “plan”, “believe” and other words and terms of similar meaning in connection with any discussion of future operating or financial performance. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual outcomes and results to differ materially from current expectations. These

 

12


factors include, among other things, market factors, competitive product development, pricing controls and pressures (including changes in rules and practices of managed care groups and institutional and governmental purchasers), economic conditions such as interest rate and currency exchange rate fluctuations, judicial decisions and governmental laws and regulations related to Medicare, Medicaid and healthcare reform, pharmaceutical rebates and reimbursement, claims and concerns that may arise regarding the safety and efficacy of in-line products and product candidates, changes to wholesaler inventory levels, changes in, and interpretation of, governmental regulations and legislation affecting domestic or foreign operations, including tax obligations, difficulties and delays in product development, manufacturing and sales, patent positions and the unpredictability of the ultimate outcome of any litigation matter, including whether the company will prevail at trial in the patent litigation with Apotex, as well as any risks associated with the criminal investigation conducted by the Department of Justice in connection with the proposed settlement with Apotex, and the launch of a generic clopidogrel bisulfate product by Apotex, including the amount of generic product distributed and the rate at which it will be utilized by prescription demand, and the time-period in which it will impact the company’s results. These factors also include the ability to realize projected cost savings and the expiration of patents on certain other products, and the impact and result of governmental investigations. There can be no guarantees with respect to pipeline products that future clinical studies will support the data described in this release, that the products will receive necessary regulatory approvals, or that they will prove to be commercially successful; nor are there guarantees that regulatory approvals will be sought, or sought within currently expected timeframes, or that contractual milestones will be achieved. For further details and a discussion of these and other risks and uncertainties, see the company’s periodic reports, including current reports on Form 8-K, quarterly reports on Form 10-Q and the annual report on Form 10-K, furnished to and filed with the Securities and Exchange Commission. The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

Company and Conference Call Information

Bristol-Myers Squibb is a global pharmaceutical and related health care products company whose mission is to extend and enhance human life.

There will be a conference call on January 25, 2007 at 10:30 a.m. (EDT) during which company executives will address inquiries from investors and analysts. Investors and the general public are invited to listen to a live webcast of the call at www.bms.com/ir or by dialing 913-981-4911. Materials related to the call will be available at the same website prior to the call.

For more information, contact: Tony Plohoros, 212-546-4379, or Jeff Macdonald, 212-546-4824, Communications, or John Elicker, 212-546-3775, or Blaine Davis, 212-546-4631, Investor Relations.

# # #

ABILIFY® is a trademark of Otsuka Pharmaceutical Co., Ltd.

AVAPRO®, AVALIDE® and PLAVIX® are trademarks of sanofi-aventis

ERBITUX® is a trademark of Imclone Systems Incorporated

EMSAM® is a trademark of Somerset Pharmaceuticals, Inc.

GLEEVEC® is a trademark of Novartis, Inc.

ATRIPLA is a trademark of both Bristol-Myers Squibb Co. and Gilead Sciences, Inc.


* Growth drivers include PLAVIX®, AVAPRO®/AVALIDE®, ABILIFY®, REYATAZ® and ERBITUX®

 

13


BRISTOL-MYERS SQUIBB COMPANY

NET SALES BY OPERATING SEGMENTS

FOR THE THREE AND TWELVE MONTHS ENDED DECEMBER 31, 2006 AND 2005

(Unaudited, dollars in millions)

 

      

Three Months

Ended December 31

    

Twelve Months

Ended December 31

     2006      2005      2006      2005

Pharmaceuticals

     $ 3,148      $ 4,012      $ 13,861      $ 15,254

Nutritionals

       618        584        2,347        2,205

Other Health Care

       447        423        1,706        1,748
                                   

Health Care Group

       1,065        1,007        4,053        3,953
                                   

Net Sales

     $ 4,213      $ 5,019      $ 17,914      $ 19,207
                                   

 

14


BRISTOL-MYERS SQUIBB COMPANY

SELECTED PRODUCTS

FOR THE THREE AND TWELVE MONTHS ENDED DECEMBER 31, 2006 AND 2005

(Unaudited, dollars in millions)

The following table sets forth worldwide and U.S. reported net sales for selected products for the three and twelve months ended December 31, 2006 compared to the three and twelve months ended December 31, 2005. In addition, the table includes, where applicable, the estimated total (both retail and mail-order customers) prescription growth, for the comparative periods presented, for certain of the company’s U.S. primary care pharmaceutical prescription products. The estimated prescription growth amounts are based on third-party data. A significant portion of the company’s U.S pharmaceutical sales is made to wholesalers. Where changes in reported net sales differ from prescription growth, this change in net sales may not reflect underlying prescriber demand.

 

     Three Months Ended December 31  
     Worldwide Net Sales     U.S. Net Sales        
     2006    2005    %
Change
    2006     2005    %
Change
    % Change in U.S. Total
Prescriptions vs. 2005
 

Pharmaceuticals

                 

Cardiovascular

                 

Plavix

   $ 496    $ 1,061    (53 )%   $ 343     $ 906    (62 )%   (64 )%

Pravachol

     146      584    (75 )%     50       366    (86 )%   (84 )%

Avapro/Avalide

     307      277    11 %     182       168    8 %   2 %

Coumadin

     57      56    2 %     48       50    (4 )%   (19 )%

Monopril

     28      46    (39 )%     (7 )     3      **   (53 )%

Virology

                 

Reyataz

     255      188    36 %     144       110    31 %   20 %

Sustiva franchise (total revenue)

     222      170    31 %     144       102    41 %   21 %

Zerit

     36      47    (23 )%     19       21    (10 )%   (27 )%

Baraclude

     36      5      **     18       4      **     **

Other Infectious Diseases

                 

Cefzil

     23      75    (69 )%     (5 )     46    (111 )%   (97 )%

Oncology

                 

Erbitux

     167      121    38 %     165       121    36 %   N/A  

Taxol

     130      181    (28 )%     2       5    (60 )%   N/A  

Sprycel

     14      —      —         11       —      —       N/A  

Affective (Psychiatric) Disorders

                 

Abilify (total revenue)

     362      224    62 %     294       175    68 %   17 %

EMSAM

     3      —      —         3       —      —       N/A  

Immunoscience

                 

Orencia

     32      —      —         31       —      —       N/A  

Other Pharmaceuticals

                 

Efferalgan

     74      74    —         —         —      —       N/A  

Nutritionals

                 

Enfamil

     271      277    (2 )%     190       184    3 %   N/A  

Enfagrow

     67      53    26 %     —         —      —       N/A  

Other Health Care

                 

Ostomy

     151      145    4 %     45       46    (2 )%   N/A  

Wound Therapeutics

     123      112    10 %     43       40    8 %   N/A  

Cardiolite

     103      100    3 %     90       88    2 %   N/A  

 

15


     Twelve Months Ended December 31  
     Worldwide Net Sales     U.S. Net Sales        
     2006    2005    %
Change
    2006     2005    %
Change
   

% Change in U.S. Total

Prescriptions vs. 2005

 

Pharmaceuticals

                 

Cardiovascular

                 

Plavix

   $ 3,257    $ 3,823    (15 )%   $ 2,655     $ 3,235    (18 )%   (18 )%

Pravachol

     1,197      2,256    (47 )%     553       1,274    (57 )%   (59 )%

Avapro/Avalide

     1,097      982    12 %     647       574    13 %   4 %

Coumadin

     220      212    4 %     186       183    2 %   (21 )%

Monopril

     159      208    (24 )%     (4 )     9    (144 )%   (54 )%

Virology

                 

Reyataz

     931      696    34 %     514       405    27 %   18 %

Sustiva franchise (total revenue)

     791      680    16 %     495       403    23 %   11 %

Zerit

     155      216    (28 )%     75       97    (23 )%   (30 )%

Baraclude

     83      12      **     50       11      **     **

Other Infectious Diseases

                 

Cefzil

     87      259    (66 )%     (10 )     153    (107 )%   (91 )%

Oncology

                 

Erbitux

     652      413    58 %     646       411    57 %   N/A  

Taxol

     563      747    (25 )%     12       17    (29 )%   N/A  

Sprycel

     25      —      —         22       —      —       N/A  

Affective (Psychiatric) Disorders

                 

Abilify (total revenue)

     1,282      912    41 %     1,052       750    40 %   21 %

EMSAM

     18      —      —         18       —      —       N/A  

Immunoscience

                 

Orencia

     89      —      —         88       —      —       N/A  

Other Pharmaceuticals

                 

Efferalgan

     266      283    (6 )%     —         —      —       N/A  

Nutritionals

                 

Enfamil

     1,007      992    2 %     688       685    —       N/A  

Enfagrow

     262      206    27 %     —         —      —       N/A  

Other Health Care

                 

Ostomy

     554      550    1 %     159       161    (1 )%   N/A  

Wound Therapeutics

     441      416    6 %     143       133    8 %   N/A  

Cardiolite

     408      416    (2 )%     358       370    (3 )%   N/A  

** Change is in excess of 200%

 

16


BRISTOL-MYERS SQUIBB COMPANY

CONSOLIDATED STATEMENTS OF EARNINGS

FOR THE THREE AND TWELVE MONTHS ENDED DECEMBER 31, 2006 AND 2005

(Unaudited, amounts in millions except per share data)

 

     Three Months Ended December 31     Twelve Months Ended December 31  
     2006     2005     2006     2005  

Net Sales

   $ 4,213     $ 5,019     $ 17,914     $ 19,207  
                                

Cost of products sold

     1,447       1,595       5,956       5,928  

Marketing, selling and administrative

     1,311       1,369       4,919       5,106  

Advertising and product promotion

     418       444       1,351       1,476  

Research and development

     821       775       3,067       2,746  

Provision for restructuring, net

     53       32       59       32  

Litigation charges, net

     346       197       302       269  

Gain on sale of businesses

     —         —         (200 )     (569 )

Equity in net income of affiliates

     (138 )     (94 )     (474 )     (334 )

Other expense/(income), net (a)

     240       (131 )     299       37  
                                
     4,498       4,187       15,279       14,691  
                                

(Loss)/Earnings from Continuing Operations Before Minority Interest and Income Taxes

     (285 )     832       2,635       4,516  

(Benefit)/provision for income taxes

     (167 )     178       610       932  

Minority interest, net of taxes

     16       155       440       592  
                                

(Loss)/Earnings from Continuing Operations

     (134 )     499       1,585       2,992  
                                

Discontinued Operations

        

Loss, net of taxes

     —         —         —         (5 )

Gain on disposal, net of taxes

     —         —         —         13  
                                
     —         —         —         8  
                                

Net (Loss)/Earnings

   $ (134 )   $ 499     $ 1,585     $ 3,000  
                                

Earnings per Common Share:

        

Basic:

        

(Loss)/Earnings from Continuing Operations

   $ (0.07 )   $ 0.26     $ 0.81     $ 1.53  

Discontinued Operations

        

Loss, net of taxes

     —         —         —         —    

Gain on disposal, net of taxes

     —         —         —         —    
                                

Net (Loss)/Earnings per Common Share

   $ (0.07 )   $ 0.26     $ 0.81     $ 1.53  
                                

Diluted:

        

(Loss)/Earnings from Continuing Operations

   $ (0.07 )   $ 0.26     $ 0.81     $ 1.52  

Discontinued Operations

        

Loss, net of taxes

     —         —         —         —    

Gain on disposal, net of taxes

     —         —         —         —    
                                

Net (Loss)/Earnings per Common Share (1), (2)

   $ (0.07 )   $ 0.26     $ 0.81     $ 1.52  
                                

Average Common Shares Outstanding:

        

Basic

     1,961       1,953       1,960       1,952  

Diluted (1), (2)

     1,961       1,983       1,963       1,983  

        

(a) Other expense/(income), net

        

Interest expense

   $ 128     $ 100     $ 498     $ 349  

Interest income

     (73 )     (52 )     (274 )     (148 )

Foreign exchange transaction losses

     6       11       6       58  

Other expense/(income), net

     179       (190 )     69       (222 )
                                
   $ 240     $ (131 )   $ 299     $ 37  
                                

(1) For the three months ended December 31, 2006, as a result of the net loss, diluted average common shares and loss per common share are equal to basic average common shares and loss per common share
(2) For the twelve months ended December 31, 2006, the assumed shares of convertible debt are not used for diluted earnings per common share calculation as the impact of convertible debt is not dilutive

 

17


APPENDIX 1

BRISTOL-MYERS SQUIBB COMPANY

SPECIFIED ITEMS

FOR THE THREE MONTHS ENDED DECEMBER 31, 2006 AND 2005

(Unaudited, dollars in millions)

Three months ended December 31, 2006

 

     Cost of
products
sold
   Research
and
development
   Provision for
restructuring,
net
   Litigation
settlement
expense/
(income)
   

Other
expense/

(income),
net

   Total  

Litigation Matters:

                

Pharmaceutical pricing and sales litigation

   $ —      $ —      $ —      $ 353     $ —      $ 353  

Claim for damages

     —        —        —        —         13      13  

Insurance recovery

     —        —        —        (7 )     —        (7 )
                                            
     —        —        —        346       13      359  

Other:

                

Debt retirement costs

     —        —        —        —         220      220  

Downsizing and streamlining of worldwide operations

     —        —        53      —         —        53  

Accelerated depreciation and asset impairment

     29      14      —        —         —        43  

Milestone payments

     —        35      —        —         —        35  
                                            
   $ 29    $ 49    $ 53    $ 346     $ 233      710  
                                      

Income taxes on items above

                   (196 )
                      

Reduction to Net Earnings from Continuing Operations

                 $ 514  
                      

Three months ended December 31, 2005

 

     Cost of
products
sold
   Research
and
development
   Provision for
restructuring,
net
   Litigation
settlement
expense
  

Other

expense/

(income),

net

    Total  

Litigation Matters:

                

Private litigation and governmental investigations

   $ —      $ —      $ —      $ 185    $ —       $ 185  

Pharmaceutical pricing and sales litigation

     —        —        —        12      —         12  
                                            
     —        —        —        197      —         197  

Other:

                

Downsizing and streamlining of worldwide operations

     1      14      32      —        —         47  

Accelerated depreciation and asset impairment

     27      12      —        —        —         39  

Upfront and milestone payments

     —        9      —        —        —         9  

Termination of muraglitazar agreement

     5      —        —        —        (143 )     (138 )
                                            
   $ 33    $ 35    $ 32    $ 197    $ (143 )     154  
                                      

Income taxes on items above

                   (52 )
                      

Reduction to Net Earnings from Continuing Operations

                 $ 102  
                      

 

18


BRISTOL-MYERS SQUIBB COMPANY

SPECIFIED ITEMS

FOR THE TWELVE MONTHS ENDED DECEMBER 31, 2006 AND 2005

(Unaudited, dollars in millions)

Twelve months ended December 31, 2006

 

     Cost of
products
sold
   Research
and
development
   Marketing,
selling and
admin.
   Provision
for
restructuring,
net
   Litigation
settlement
expense/
(income)
   

Other
expense/

(income),
net

   Gain on
sale of
product
asset
    Total  

Litigation Matters:

                     

Pharmaceutical pricing and sales litigation

   $ —      $ —      $ —      $ —      $ 353     $ —      $ —       $ 353  

Product liability

     —        —        —        —        —         11      —         11  

Claim for damages

     —        —        —        —        —         13      —         13  

Commercial litigations

     —        —        —        —        (14 )     —        —         (14 )

Insurance recovery

     —        —        —        —        (37 )     —        —         (37 )
                                                           
     —        —        —        —        302       24      —         326  

Other:

                     

Debt retirement costs

     —        —        —        —        —         220      —         220  

Accelerated depreciation, asset impairment and contract termination

     167      15      4      —        —         —        —         186  

Upfront and milestone payments

     —        70      —        —        —         —        —         70  

Downsizing and streamlining of worldwide operations

     —        —        —        59      —         —        —         59  

Gain on sale of product asset

     —        —        —        —        —         —        (200 )     (200 )
                                                           
   $ 167    $ 85    $ 4    $ 59    $ 302     $ 244    $ (200 )     661  
                                                     

Income taxes on items above

                        (149 )

Change in estimate for taxes on prior year items

                        39  
                           

Reduction to Net Earnings from Continuing Operations

                      $ 551  
                           

Twelve months ended December 31, 2005

 

     Cost of
products
sold
   Research
and
development
   Provision for
restructuring,
net
   Gain on
sale of
business
    Litigation
settlement
expense/
(income)
   

Other
expense/

(income),
net

    Total  

Litigation Matters:

                 

Private litigation and governmental investigations

   $ —      $ —      $ —      $ —       $ 558     $ —       $ 558  

ERISA liability and other matters

     —        —        —        —         20       —         20  

Pharmaceutical pricing and sales litigation

     —        —        —        —         12       —         12  

Insurance recoveries

     —        —        —        —         (321 )     —         (321 )
                                                     
     —        —        —        —         269       —         269  

Other:

                 

Accelerated depreciation and asset impairment

     96      14      —        —         —         —         110  

Debt retirement costs

     —        —        —        —         —         69       69  

Downsizing and streamlining of worldwide operations

     1      14      32      —         —         —         47  

Upfront and milestone payments

     —        44      —        —         —         —         44  

Loss on sale of fixed assets

     —        —        —        —         —         18       18  

Gain on sale of equity investment

     —        —        —        —         —         (27 )     (27 )

Termination of muraglitazar agreement

     5      —        —        —         —         (143 )     (138 )

Gain on sale of Consumer Medicines businesses

     —        —        —        (569 )     —         —         (569 )
                                                     
   $ 102    $ 72    $ 32    $ (569 )   $ 269     $ (83 )     (177 )
                                               

Income taxes on items above

                    126  

Adjustment on taxes on repatriation of foreign earnings

                    (135 )
                       

Increase to Net Earnings from Continuing Operations

                  $ (186 )
                       

 

19

EX-99.2 3 dex992.htm CERTAIN SUPPLEMENTAL INFORMATION POSTED ON BRISTOL-MYERS SQUIBB WEBSITE Certain supplemental information posted on Bristol-Myers Squibb website

Exhibit 99.2

BRISTOL-MYERS SQUIBB COMPANY

NET SALES FROM CONTINUING OPERATIONS

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

Net Sales   2005     2006    

%

Change

 
    1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year     1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year    

Qtr
vs.

Qtr

    YTD
vs.
YTD
 

Pharmaceuticals

  $ 3,578     $ 3,886     $ 7,464     $ 3,778     $ 11,242     $ 4,012     $ 15,254     $ 3,700     $ 3,859     $ 7,559     $ 3,154     $ 10,713     $ 3,148     $ 13,861     -22 %   -9 %

US Pharmaceuticals

    1,767       2,084       3,851       2,069       5,920       2,220       8,140       2,064       2,197       4,261       1,609       5,870       1,501       7,371     -32 %   -9 %

Primary Care

    1,258       1,539       2,797       1,486       4,283       1,653       5,936       1,409       1,441       2,850       819       3,669       648       4,317     -61 %   -27 %

Oncology/Virology

    348       345       693       370       1,063       391       1,454       419       458       877       494       1,371       525       1,896     34 %   30 %

Neuroscience

    161       200       361       213       574       176       750       231       280       511       262       773       297       1,070     69 %   43 %

Immunoscience

    —         —         —         —         —         —         —         5       18       23       34       57       31       88     —       —    

Europe and Middle East Medicines

    1,201       1,112       2,313       1,030       3,343       1,053       4,396       1,024       1,000       2,024       886       2,910       934       3,844     -11 %   -13 %

Latin America/Canada

    258       306       564       285       849       325       1,174       288       303       591       300       891       306       1,197     -6 %   2 %

Asia/Pacific Medicines

    157       161       318       176       494       171       665       149       163       312       170       482       176       658     3 %   -1 %

Japan Medicines

    142       168       310       166       476       183       659       130       157       287       148       435       173       608     -5 %   -8 %

Nutritionals

    526       548       1,074       547       1,621       584       2,205       565       582       1,147       582       1,729       618       2,347     6 %   6 %

Other Health Care

    428       455       883       442       1,325       423       1,748       411       430       841       418       1,259       447       1,706     6 %   -2 %

ConvaTec

    228       247       475       250       725       267       992       230       262       492       265       757       291       1,048     9 %   6 %

Medical Imaging

    145       151       296       150       446       156       602       181       168       349       153       502       156       658     —       9 %

Consumer Medicines

    55       57       112       42       154       —         154       —         —         —         —         —         —         —       —       -100 %

Total Company

  $ 4,532     $ 4,889     $ 9,421     $ 4,767     $ 14,188     $ 5,019     $ 19,207     $ 4,676     $ 4,871     $ 9,547     $ 4,154     $ 13,701     $ 4,213     $ 17,914     -16 %   -7 %
% of Total Sales   2005     2006     Basis
Point
Change
 
    1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year     1st Qtr     2nd Qtr     6 Months     3rd Qtr     9 Months     4th Qtr     Year     Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Pharmaceuticals

    79.0 %     79.5 %     79.2 %     79.3 %     79.2 %     79.9 %     79.4 %     79.1 %     79.2 %     79.2 %     75.9 %     78.2 %     74.7 %     77.4 %   (520 )   (200 )

US Pharmaceuticals

    39.0 %     42.6 %     40.9 %     43.4 %     41.7 %     44.2 %     42.4 %     44.1 %     45.1 %     44.6 %     38.7 %     42.8 %     35.6 %     41.1 %   (860 )   (130 )

Primary Care

    27.8 %     31.4 %     29.7 %     31.2 %     30.2 %     32.9 %     30.9 %     30.1 %     29.6 %     29.9 %     19.7 %     26.8 %     15.4 %     24.1 %   (1750 )   (680 )

Oncology/Virology

    7.7 %     7.1 %     7.4 %     7.8 %     7.5 %     7.8 %     7.6 %     9.0 %     9.4 %     9.2 %     11.9 %     10.0 %     12.5 %     10.5 %   470     290  

Neuroscience

    3.5 %     4.1 %     3.8 %     4.4 %     4.0 %     3.5 %     3.9 %     4.9 %     5.7 %     5.3 %     6.3 %     5.6 %     7.0 %     6.0 %   350     210  

Immunoscience

    —         —         —         —         —         —         —         0.1 %     0.4 %     0.2 %     0.8 %     0.4 %     0.7 %     0.5 %   70     50  

Europe and Middle East Medicines

    26.5 %     22.7 %     24.6 %     21.6 %     23.6 %     21.0 %     22.9 %     21.9 %     20.5 %     21.2 %     21.3 %     21.2 %     22.2 %     21.5 %   120     (140 )

Latin America/Canada

    5.7 %     6.3 %     6.0 %     6.0 %     6.0 %     6.5 %     6.1 %     6.2 %     6.2 %     6.2 %     7.2 %     6.5 %     7.3 %     6.7 %   80     60  

Asia/Pacific Medicines

    3.5 %     3.3 %     3.4 %     3.7 %     3.5 %     3.4 %     3.5 %     3.2 %     3.4 %     3.3 %     4.1 %     3.5 %     4.2 %     3.7 %   80     20  

Japan Medicines

    3.1 %     3.4 %     3.3 %     3.5 %     3.3 %     3.7 %     3.4 %     2.8 %     3.2 %     3.0 %     3.6 %     3.2 %     4.1 %     3.4 %   40         

Nutritionals

    11.6 %     11.2 %     11.4 %     11.5 %     11.4 %     11.7 %     11.5 %     12.1 %     12.0 %     12.0 %     14.0 %     12.6 %     14.7 %     13.1 %   300     160  

Other Health Care

    9.4 %     9.3 %     9.4 %     9.2 %     9.4 %     8.4 %     9.1 %     8.8 %     8.8 %     8.8 %     10.1 %     9.2 %     10.6 %     9.5 %   220     40  

ConvaTec

    5.0 %     5.0 %     5.1 %     5.2 %     5.1 %     5.3 %     5.2 %     4.9 %     5.4 %     5.2 %     6.4 %     5.5 %     6.9 %     5.8 %   160     60  

Medical Imaging

    3.2 %     3.1 %     3.1 %     3.1 %     3.2 %     3.1 %     3.1 %     3.9 %     3.4 %     3.6 %     3.7 %     3.7 %     3.7 %     3.7 %   60     60  

Consumer Medicines

    1.2 %     1.2 %     1.2 %     0.9 %     1.1 %     —         0.8 %     —         —         —         —         —                                (80 )

Total Company

    100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %     100.0 %    


BRISTOL-MYERS SQUIBB COMPANY

SEGMENT SALES AND COMPOSITION OF CHANGE IN SALES FOR CONTINUING OPERATIONS

FOR THE PERIOD ENDED DECEMBER 31, 2006

($ in millions)

 

QUARTER-TO-DATE   
     Pharmaceuticals
Group
    Nutritionals     Convatec     Medical Imaging    

Consumer

Medicines

    Continuing
Operations
 

Price Increases/(Decreases)

     —         3 %     1 %     -1 %     —         —    

Foreign Exchange

     1 %     2 %     4 %     1 %     —         2 %

Volume

     -23 %     1 %     4 %     —         —         -18 %
                                                

Total Change

     -22 %     6 %     9 %     —         —         -16 %
                                                

Total 2006 Period to Date Sales

   $ 3,148     $ 618     $ 291     $ 156     $ —       $ 4,213  

Total 2005 Period to Date Sales

   $ 4,012     $ 584     $ 267     $ 156     $ —       $ 5,019  
YEAR-TO-DATE             
     Pharmaceuticals
Group
    Nutritionals     Convatec     Medical Imaging     Consumer
Medicines
    Continuing
Operations
 

Price Increases/(Decreases)

     2 %     3 %     —         -2 %     —         2 %

Foreign Exchange

     —         1 %     1 %     —         —         —    

Volume

     -11 %     2 %     5 %     11 %     -100 %     -9 %
                                                

Total Change

     -9 %     6 %     6 %     9 %     -100 %     -7 %
                                                

Total 2006 Period to Date Sales

   $ 13,861     $ 2,347     $ 1,048     $ 658     $ —       $ 17,914  

Total 2005 Period to Date Sales

   $ 15,254     $ 2,205     $ 992     $ 602     $ 154     $ 19,207  


BRISTOL-MYERS SQUIBB COMPANY

CONSOLIDATED STATEMENT OF EARNINGS

CONTINUING OPERATIONS

($ in millions, except per share amounts)

 

    2005     2006    

%

Change

 
    1st
Qtr
    2nd
Qtr
    6
Months
    3rd
Qtr
    9
Months
    4th
Qtr
    Year     1st
Qtr
    2nd
Qtr
    6
Months
    3rd
Qtr
    9
Months
   

4th

Qtr

    Year     Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Net Sales

  $ 4,532     $ 4,889     $ 9,421     $ 4,767     $ 14,188     $ 5,019     $ 19,207     $ 4,676     $ 4,871     $ 9,547     $ 4,154     $ 13,701     $ 4,213     $ 17,914     -16 %   -7 %

Cost of products sold

    1,367       1,483       2,850       1,483       4,333       1,595       5,928       1,476       1,568       3,044       1,465       4,509       1,447       5,956     -9 %   0 %

Marketing, selling and administrative

    1,183       1,268       2,451       1,286       3,737       1,369       5,106       1,238       1,181       2,419       1,189       3,608       1,311       4,919     -4 %   -4 %

Advertising and product promotion

    318       365       683       349       1,032       444       1,476       295       352       647       286       933       418       1,351     -6 %   -8 %

Research and development

    653       649       1,302       669       1,971       775       2,746       750       740       1,490       756       2,246       821       3,067     6 %   12 %

Provision for restructuring, net

    3       2       5       (5 )     —         32       32       1       3       4       2       6       53       59     66 %   84 %

Litigation (income)/charges, net

    124       (26 )     98       (26 )     72       197       269       (21 )     (14 )     (35 )     (9 )     (44 )     346       302     76 %   12 %

Gain on sale of business and product asset

    —         —         —         (569 )     (569 )     —         (569 )     (200 )     —         (200 )     —         (200 )     —         (200 )   —       65 %

Equity in net income of affiliates

    (69 )     (87 )     (156 )     (84 )     (240 )     (94 )     (334 )     (93 )     (125 )     (218 )     (118 )     (336 )     (138 )     (474 )   -47 %   -42 %

Other (income)/expense, net

    25       105       130       38       168       (131 )     37       37       56       93       (34 )     59       240       299     *     *  
                                                                                                                           

Total expenses

    3,604       3,759       7,363       3,141       10,504       4,187       14,691       3,483       3,761       7,244       3,537       10,781       4,498       15,279     7 %   4 %
                                                                                                                           

(Loss)/Earnings from Continuing Operations

Before Minority Interest and Income Taxes

    928       1,130       2,058       1,626       3,684       832       4,516       1,193       1,110       2,303       617       2,920       (285 )     2,635     -134 %   -42 %

(Benefit)/Provision for income taxes

    268       (21 )     247       507       754       178       932       328       256       584       193       777       (167 )     610     -194 %   -35 %

Minority interest, net of taxes

    122       160       282       155       437       155       592       151       187       338       86       424       16       440     -90 %   -26 %
                                                                                                                           

(Loss)/Earnings from Continuing Operations

  $ 538     $ 991     $ 1,529     $ 964     $ 2,493     $ 499     $ 2,992     $ 714     $ 667     $ 1,381     $ 338     $ 1,719     ($ 134 )   $ 1,585     -127 %   -47 %
                                                                                                                           

Interest expense on conversion of convertible debt bonds, net of tax

    4       5       9       6       15       7       22       8       8       16       9       25       —   (1)     —   (2)    
                                                                                                                   

(Loss)/Earnings from continuing operations used for diluted earnings per common share calculation

  $ 542     $ 996     $ 1,538     $ 970     $ 2,508     $ 506     $ 3,014     $ 722     $ 675     $ 1,397     $ 347     $ 1,744     ($ 134 )(1)   $ 1,585 (2)    
                                                                                                                   

Diluted (Loss)/Earnings per Common Share Continuing Operations**

  $ 0.27     $ 0.50     $ 0.78     $ 0.49     $ 1.27     $ 0.26     $ 1.52     $ 0.36     $ 0.34     $ 0.70     $ 0.17     $ 0.88     ($ 0.07 )(1)   $ 0.81 (2)   -127 %   -47 %

Average Common Shares Outstanding - Diluted

    1,981       1,984       1,982       1,984       1,983       1,983       1,983       1,988       1,994       1,992       1,992       1,991       1,961  (1)     1,963  (2)   -1 %   -1 %

Dividends declared per common share

  $ 0.28     $ 0.28     $ 0.56     $ 0.28     $ 0.84     $ 0.28     $ 1.12     $ 0.28     $ 0.28     $ 0.56     $ 0.28     $ 0.84     $ 0.28     $ 1.12     —       —    
                                                                                                                           
% of Net Sales   2005     2006     Basis
Point
Change
 
    1st
Qtr
    2nd
Qtr
    6
Months
    3rd
Qtr
    9
Months
    4th
Qtr
    Year     1st
Qtr
    2nd
Qtr
    6
Months
    3rd
Qtr
    9
Months
   

4th

Qtr

    Year     Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Gross Margin

    69.8 %     69.7 %     69.7 %     68.9 %     69.5 %     68.2 %     69.1 %     68.4 %     67.8 %     68.1 %     64.7 %     67.1 %     65.7 %     66.8 %   (250 )   (230 )

Cost of products sold

    30.2 %     30.3 %     30.3 %     31.1 %     30.5 %     31.8 %     30.9 %     31.6 %     32.2 %     31.9 %     35.3 %     32.9 %     34.3 %     33.2 %   250     230  

Marketing, selling and administrative

    26.1 %     25.9 %     26.0 %     27.0 %     26.3 %     27.3 %     26.6 %     26.5 %     24.2 %     25.3 %     28.6 %     26.3 %     31.1 %     27.5 %   380     90  

Advertising and product promotion

    7.0 %     7.5 %     7.2 %     7.3 %     7.3 %     8.8 %     7.7 %     6.3 %     7.2 %     6.8 %     6.9 %     6.8 %     9.9 %     7.5 %   110     (20 )

Research and development

    14.4 %     13.3 %     13.8 %     14.0 %     13.9 %     15.4 %     14.3 %     16.0 %     15.2 %     15.6 %     18.2 %     16.4 %     19.5 %     17.1 %   410     280  

Total expenses

    79.5 %     76.9 %     78.2 %     65.9 %     74.0 %     83.4 %     76.5 %     74.5 %     77.2 %     75.9 %     85.1 %     78.7 %     106.8 %     85.3 %   2,340     880  

(Loss)/Earnings from Continuing Operations
Before Minority Interest and Provision
for Income Taxes

    20.5 %     23.1 %     21.8 %     34.1 %     26.0 %     16.6 %     23.5 %     25.5 %     22.8 %     24.1 %     14.9 %     21.3 %     -6.8 %     14.7 %   (2,340 )   (880 )

(Loss)/Earnings from Continuing Operations

    11.9 %     20.3 %     16.2 %     20.2 %     17.6 %     9.9 %     15.6 %     15.3 %     13.7 %     14.5 %     8.1 %     12.5 %     -3.2 %     8.8 %   (1,310 )   (680 )

Other Ratios

                               

Effective Tax Rate

    28.9 %     -1.9 %     12.0 %     31.2 %     20.5 %     21.4 %     20.6 %     27.5 %     23.1 %     25.4 %     31.3 %     26.6 %     58.6 %     23.1 %    
                                                                                                                   
Other (Income)/Expense, net   2005     2006    

%

Change

 
    1st
Qtr
    2nd
Qtr
    6
Months
    3rd
Qtr
    9
Months
    4th
Qtr
    Year     1st
Qtr
    2nd
Qtr
    6
Months
    3rd
Qtr
    9
Months
    4th Qtr     Year     Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Interest expense

  $ 97     $ 73     $ 170     $ 79     $ 249     $ 100     $ 349     $ 116     $ 124     $ 240     $ 130     $ 370     $ 128     $ 498     28 %   43 %

Interest income

    (45 )     (23 )     (68 )     (28 )     (96 )     (52 )     (148 )     (62 )     (65 )     (127 )     (74 )     (201 )     (73 )     (274 )   -40 %   -85 %

Foreign exchange transaction (gains)/losses

    12       35       47       —         47       11       58       (12 )     23       11       (11 )     —         6       6     -45 %   -90 %

Other (income)/expense, net

    (39 )     20       (19 )     (13 )     (32 )     (190 )     (222 )     (5 )     (26 )     (31 )     (79 )     (110 )     179       69     194 %   131 %
                                                                                                                           
  $ 25     $ 105     $ 130     $ 38     $ 168     ($ 131 )   $ 37     $ 37     $ 56     $ 93     ($ 34 )   $ 59     $ 240     $ 299       *     *
                                                                                                                           

* in excess of +/- 200%
** amounts may not calculate due to rounding differences between continuing and discontinued operations.
(1) as a result of the Q4 2006 net loss, Diluted Average Common Shares Outstanding and Loss per Common Share are equal to Basic Average Common Shares Outstanding and Loss per Common Share.
(2) assumed interest amount and the assumed conversion of convertible debt are not used for Diluted Earnings per Common Share calculation as the impact of convertible debt is not dilutive.


BRISTOL-MYERS SQUIBB COMPANY

WORLDWIDE NET SALES FROM CONTINUING OPERATIONS BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

     2005    2006    % Change  
     1st Qtr    2nd Qtr    6 Months    3rd Qtr    9 Months    4th Qtr    Year    1st Qtr    2nd Qtr    6 Months    3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Total Company

   $ 4,532    $ 4,889    $ 9,421    $ 4,767    $ 14,188    $ 5,019    $ 19,207    $ 4,676    $ 4,871    $ 9,547    $ 4,154    $ 13,701    $ 4,213    $ 17,914    -16 %   -7 %

PHARMACEUTICALS

     3,578      3,886      7,464      3,778      11,242      4,012      15,254      3,700      3,859      7,559      3,154      10,713      3,148      13,861    -22 %   -9 %

Cardiovascular

     1,712      2,031      3,743      1,935      5,678      2,090      7,768      1,917      1,907      3,824      1,239      5,063      1,093      6,156    -48 %   -21 %

Plavix

     814      968      1,782      980      2,762      1,061      3,823      986      1,145      2,131      630      2,761      496      3,257    -53 %   -15 %

Pravachol

     520      625      1,145      527      1,672      584      2,256      536      323      859      192      1,051      146      1,197    -75 %   -47 %

Avapro/ Avalide

     196      258      454      251      705      277      982      233      280      513      277      790      307      1,097    11 %   12 %

Coumadin

     49      50      99      57      156      56      212      55      55      110      53      163      57      220    2 %   4 %

Monopril

     59      54      113      49      162      46      208      48      49      97      34      131      28      159    -39 %   -24 %

Virology

     430      457      887      440      1,327      450      1,777      468      524      992      532      1,524      580      2,104    29 %   18 %

Reyataz

     149      183      332      176      508      188      696      207      236      443      233      676      255      931    36 %   34 %

Sustiva Franchise*****

     173      167      340      170      510      170      680      175      193      368      201      569      222      791    31 %   16 %

Zerit

     59      59      118      51      169      47      216      40      41      81      38      119      36      155    -23 %   -28 %

Baraclude

     —        5      5      2      7      5      12      11      14      25      22      47      36      83      ***     ***

Infectious Diseases

     293      261      554      239      793      286      1,079      199      172      371      169      540      159      699    -44 %   -35 %

Cefzil

     82      54      136      48      184      75      259      23      23      46      18      64      23      87    -69 %   -66 %

Oncology

     387      371      758      380      1,138      395      1,533      361      401      762      399      1,161      394      1,555           1 %

Erbitux

     87      98      185      107      292      121      413      138      172      310      175      485      167      652    38 %   58 %

Taxol

     205      186      391      175      566      181      747      147      149      296      137      433      130      563    -28 %   -25 %

Sprycel

     —        —        —        —        —                        —        —        —        11      11      14      25               

Affective (Psychiatric) Disorders

     232      284      516      306      822      267      1,089      323      376      699      354      1,053      404      1,457    51 %   34 %

Abilify**

     188      240      428      260      688      224      912      283      324      607      313      920      362      1,282    62 %   41 %

EMSAM

     —        —        —        —        —                        —        12      12      3      15      3      18               

Immunoscience

     —        —        —        —        —                        5      18      23      34      57      32      89               

Orencia

        —        —        —        —                        5      18      23      34      57      32      89               

Other Pharmaceuticals

                                              

Efferalgan

     88      55      143      66      209      74      283      68      62      130      62      192      74      266           -6 %

NUTRITIONALS

     526      548      1,074      547      1,621      584      2,205      565      582      1,147      582      1,729      618      2,347    6 %   6 %

Enfamil

     235      250      485      230      715      277      992      237      253      490      246      736      271      1,007    -2 %   2 %

Enfagrow

     50      49      99      54      153      53      206      67      59      126      69      195      67      262    26 %   27 %

OTHER HEALTH CARE

     428      455      883      442      1,325      423      1,748      411      430      841      418      1,259      447      1,706    6 %   -2 %

CONVATEC

     228      247      475      250      725      267      992      230      262      492      265      757      291      1,048    9 %   6 %

Ostomy

     127      139      266      139      405      145      550      123      141      264      139      403      151      554    4 %   1 %

Wound Therapeutics

     97      103      200      104      304      112      416      98      107      205      113      318      123      441    10 %   6 %

MEDICAL IMAGING

     145      151      296      150      446      156      602      181      168      349      153      502      156      658           9 %

Cardiolite

     102      108      210      106      316      100      416      103      105      208      97      305      103      408    3 %   -2 %

CONSUMER MEDICINES

     55      57      112      42      154              154      —        —        —        —        —                             -100 %
                                                                                                              

** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** In excess of +/- 200%
***** Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc.


BRISTOL-MYERS SQUIBB COMPANY

DOMESTIC* NET SALES FROM CONTINUING OPERATIONS BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

          % Change in U.S.
Total
Prescription****
 
    2005   2006     %
Change
    NPA     NGPS  
    1st
Qtr
  2nd
Qtr
  6
Months
  3rd
Qtr
  9
Months
  4th
Qtr
  Year   1st
Qtr
    2nd
Qtr
    6
Months
    3rd
Qtr
  9
Months
    4th
Qtr
    Year     Qtr
vs.
Qtr
    YTD
vs.
YTD
    Qtr
vs.
Qtr
    YTD
vs.
YTD
    Qtr
vs.
Qtr
    YTD
vs.
YTD
 

Total Company

  $ 2,310   $ 2,668   $ 4,978   $ 2,638   $ 7,616   $ 2,845   $ 10,461   $ 2,638     $ 2,806     $ 5,444     $ 2,170   $ 7,614     $ 2,115     $ 9,729     -26 %   -7 %        

PHARMACEUTICALS

    1,777     2,097     3,874     2,082     5,956     2,234     8,190     2,076       2,205       4,281       1,619     5,900       1,517       7,417     -32 %   -9 %        

Cardiovascular

    1,080     1,377     2,457     1,328     3,785     1,496     5,281     1,341       1,330       2,671       752     3,423       616       4,039     -59 %   -24 %        

Plavix

    673     823     1,496     833     2,329     906     3,235     850       988       1,838       474     2,312       343       2,655     -62 %   -18 %   -64 %   -18 %   -66 %   -20 %

Pravachol

    258     353     611     297     908     366     1,274     302       128       430       73     503       50       553     -86 %   -57 %   -84 %   -59 %   -84 %   -59 %

Avapro/ Avalide

    102     157     259     147     406     168     574     139       167       306       159     465       182       647     8 %   13 %   2 %   4 %   1 %   2 %

Coumadin

    42     42     84     49     133     50     183     47       46       93       45     138       48       186     -4 %   2 %   -19 %   -21 %   -18 %   -22 %

Monopril

    3     2     5     1     6     3     9     2       1       3       —       3       (7 )     (4 )   * **   -144 %   -53 %   -54 %   -51 %   -54 %

Virology

    231     231     462     239     701     244     945     259       270       529       292     821       327       1,148     34 %   21 %        

Reyataz

    92     98     190     105     295     110     405     119       122       241       129     370       144       514     31 %   27 %   20 %   18 %   15 %   17 %

Sustiva Franchise*****

    103     97     200     101     301     102     403     108       115       223       128     351       144       495     41 %   23 %   21 %   11 %   20 %   11 %

Zerit

    26     26     52     24     76     21     97     19       18       37       19     56       19       75     -10 %   -23 %   -27 %   -30 %   -28 %   -30 %

Baraclude

    —       5     5     2     7     4     11     9       9       18       14     32       18       50       ***     ***     ***     ***   198 %     ***

Infectious Diseases

    91     57     148     53     201     75     276     12       (3 )     9       25     34       (31 )     3     -141 %   -99 %        

Cefzil

    50     30     80     27     107     46     153     (5 )     (1 )     (6 )     1     (5 )     (5 )     (10 )   -111 %   -107 %   -97 %   -91 %   -97 %   -91 %

Oncology

    115     112     227     131     358     144     502     159       187       346       201     547       195       742     35 %   48 %        

Erbitux

    87     97     184     106     290     121     411     136       172       308       173     481       165       646     36 %   57 %   N/A     N/A     N/A     N/A  

Taxol

    4     4     8     4     12     5     17     4       4       8       2     10       2       12     -60 %   -29 %   N/A     N/A     N/A     N/A  

Sprycel

    —       —       —       —       —       —       —       —         —         —         11     11       11       22     —       —       N/A     N/A     N/A     N/A  

Affective (Psychiatric) Disorders

    167     206     373     221     594     183     777     237       286       523       266     789       302       1,091     65 %   40 %        

Abilify**

    161     200     361     214     575     175     750     231       267       498       260     758       294       1,052     68 %   40 %   17 %   21 %   17 %   21 %

EMSAM

    —       —       —       —       —       —       —       —         12       12       3     15       3       18     —       —       N/A     N/A     N/A     N/A  

Immunoscience

    —       —       —       —       —       —       —       5       18       23       34     57       31       88     —       —            

Orencia

    —       —       —       —       —       —       —       5       18       23       34     57       31       88     —       —       N/A     N/A     N/A     N/A  

Other Pharmaceuticals

                                       

Efferalgan

    —       —       —       —       —       —       —       —         —         —         —       —         —         —       —       —       N/A     N/A     N/A     N/A  

NUTRITIONALS

    255     267     522     266     788     282     1,070     247       282       529       267     796       295       1,091     5 %   2 %        

Enfamil

    162     171     333     168     501     184     685     155       174       329       169     498       190       688     3 %   —       N/A     N/A     N/A     N/A  

Enfagrow

    —       —       —       —       —       —       —       —         —         —         —       —         —         —       —       —       N/A     N/A     N/A     N/A  

OTHER HEALTH CARE

    242     253     495     252     747     225     972     231       226       457       215     672       232       904     3 %   -7 %        

CONVATEC

    66     71     137     82     219     93     312     73       85       158       84     242       101       343     9 %   10 %        

Ostomy

    34     38     72     43     115     46     161     34       41       75       39     114       45       159     -2 %   -1 %   N/A     N/A     N/A     N/A  

Wound Therapeutics

    30     29     59     34     93     40     133     30       34       64       36     100       43       143     8 %   8 %   N/A     N/A     N/A     N/A  

MEDICAL IMAGING

    124     127     251     129     380     132     512     158       141       299       131     430       131       561     -1 %   10 %        

Cardiolite

    91     96     187     95     282     88     370     91       91       182       86     268       90       358     2 %   -3 %   N/A     N/A     N/A     N/A  

CONSUMER MEDICINES

    52     55     107     41     148     —       148     —         —         —         —       —         —         —       —       -100 %        
                                                                                                                   

* This table presents Total Company sales on a legal entity source basis and segment and product sales on a country management reported basis.

As a result, the sum of segment sales does not tie to Total Company sales.

** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** In excess of +/- 200%
**** The estimated total U.S. prescription growth for the retail and mail order channels are calculated based on National Prescription Audit (NPA) and Next-Generation Prescription Services (NGPS) data provided by IMS Health, a supplier of market research for the pharmaceutical industry. The NPA data is based on a simple average of the estimated number of prescriptions in the retail and mail order channels, and the NGPS data is based on a weighted average of the estimated number of prescription units (pills) in each of the retail and mail order channels as provided by IMS.
***** Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc. The change in U.S. total prescriptions growth for the Sustiva Franchise includes both branded Sustiva and Atripla prescription units.


BRISTOL-MYERS SQUIBB COMPANY

INTERNATIONAL* NET SALES FROM CONTINUING OPERATIONS BY PRODUCT

QUARTERLY SALES TREND ANALYSIS

($ in millions)

 

     2005    2006    % Change  
     1st Qtr    2nd Qtr    6 Months    3rd Qtr    9 Months    4th Qtr    Year    1st Qtr    2nd Qtr    6 Months    3rd Qtr    9 Months    4th Qtr    Year    Qtr vs. Qtr     YTD vs. YTD  

Total Company

   $ 2,222    $ 2,221    $ 4,443    $ 2,129    $ 6,572    $ 2,174    $ 8,746    $ 2,038    $ 2,065    $ 4,103    $ 1,984    $ 6,087    $ 2,098    $ 8,185    -3 %   -6 %

PHARMACEUTICALS

     1,801      1,789      3,590      1,696      5,286      1,778      7,064      1,624      1,654      3,278      1,535      4,813      1,631      6,444    -8 %   -9 %

Cardiovascular

     632      654      1,286      607      1,893      594      2,487      576      577      1,153      487      1,640      477      2,117    -20 %   -15 %

Plavix

     141      145      286      147      433      155      588      136      157      293      156      449      153      602    -1 %   2 %

Pravachol

     262      272      534      230      764      218      982      234      195      429      119      548      96      644    -56 %   -34 %

Avapro/Avalide

     94      101      195      104      299      109      408      94      113      207      118      325      125      450    15 %   10 %

Coumadin

     7      8      15      8      23      6      29      8      9      17      8      25      9      34    50 %   17 %

Monopril

     56      52      108      48      156      43      199      46      48      94      34      128      35      163    -19 %   -18 %

Virology

     199      226      425      201      626      206      832      209      254      463      240      703      253      956    23 %   15 %

Reyataz

     57      85      142      71      213      78      291      88      114      202      104      306      111      417    42 %   43 %

Sustiva Franchise*****

     70      70      140      69      209      68      277      67      78      145      73      218      78      296    15 %   7 %

Zerit

     33      33      66      27      93      26      119      21      23      44      19      63      17      80    -35 %   -33 %

Baraclude

     —        —        —        —        —        1      1      2      5      7      8      15      18      33      ***     ***

Infectious Diseases

     202      204      406      186      592      211      803      187      175      362      144      506      190      696    -10 %   -13 %

Cefzil

     32      24      56      21      77      29      106      28      24      52      17      69      28      97    -3 %   -8 %

Oncology

     272      259      531      249      780      251      1,031      202      214      416      198      614      199      813    -21 %   -21 %

Erbitux

     —        1      1      1      2      —        2      2      —        2      2      4      2      6    —       200 %

Taxol

     201      182      383      171      554      176      730      143      145      288      135      423      128      551    -27 %   -25 %

Sprycel

     —        —        —        —        —        —        —        —        —        —        —        —        3      3    —       —    

Affective (Psychiatric) Disorders

     65      78      143      85      228      84      312      86      90      176      88      264      102      366    21 %   17 %

Abilify**

     27      40      67      46      113      49      162      52      57      109      53      162      68      230    39 %   42 %

EMSAM

     —        —        —        —        —        —        —        —        —        —        —        —        —        —      —       —    

Immunoscience

     —        —        —        —        —        —        —        —        —        —        —        —        1      1    —       —    

Orencia

     —        —        —        —        —        —        —        —        —        —        —        —        1      1    —       —    

Other Pharmaceuticals

                                              

Efferalgan

     88      55      143      66      209      74      283      68      62      130      62      192      74      266    —       -6 %

NUTRITIONALS

     271      281      552      281      833      302      1,135      318      300      618      315      933      323      1,256    7 %   11 %

Enfamil

     73      79      152      62      214      93      307      82      79      161      77      238      81      319    -13 %   4 %

Enfagrow

     50      49      99      54      153      53      206      67      59      126      69      195      67      262    26 %   27 %

OTHER HEALTH CARE

     186      202      388      190      578      198      776      180      204      384      203      587      215      802    9 %   3 %

CONVATEC

     162      176      338      168      506      174      680      157      177      334      181      515      190      705    9 %   4 %

Ostomy

     93      101      194      96      290      99      389      89      100      189      100      289      106      395    7 %   2 %

Wound Therapeutics

     67      74      141      70      211      72      283      68      73      141      77      218      80      298    11 %   5 %

MEDICAL IMAGING

     21      24      45      21      66      24      90      23      27      50      22      72      25      97    4 %   8 %

Cardiolite

     11      12      23      11      34      12      46      12      14      26      11      37      13      50    8 %   9 %

CONSUMER MEDICINES

     3      2      5      1      6      —        6      —        —        —        —        —        —        —      —       -100 %
                                                                                                              

* This table presents Total Company sales on a legal entity source basis and segment and product sales on a country management reported basis.

As a result, the sum of segment sales does not tie to Total Company sales.

** Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd.
*** In excess of +/- 200%
***** Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc.


BRISTOL-MYERS SQUIBB COMPANY

U.S. PHARMACEUTICALS NET SALES

EXCLUDING ESTIMATED IMPACT OF LAUNCH OF GENERIC CLOPIDOGREL BISULFATE

($ in millions)

 

     2006    2005    % Change
     Q4    Q4    Qtr vs. Qtr

U.S Pharmaceuticals Net Sales

        

U.S Pharmaceuticals Net Sales as Reported

   $ 1,501    $ 2,220    -32%

Estimated Impact of Launch of Generic Clopidogrel Bisulfate

     700 to 750      —      —  
                  

U.S Pharmaceuticals Net Sales Excluding the Estimated Impact of Launch of Generic Clopidogrel Bisulfate

   $ 2,201 to $2,251    $ 2,220    -1% to 1%
                  


BRISTOL-MYERS SQUIBB COMPANY

GROSS MARGIN

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Net Sales

   $ 4,676     $ 4,871     $ 4,154     $ 4,213     $ 17,914  
                                        

Gross Profit

          

Gross Profit

   $ 3,200     $ 3,303     $ 2,689     $ 2,766     $ 11,958  

Specified items*

     46       20       72       29       167  
                                        

Gross Profit Excluding Specified Items

   $ 3,246     $ 3,323     $ 2,761     $ 2,795     $ 12,125  
                                        

Gross Margin %

          

Gross Margin %

     68.4 %     67.8 %     64.7 %     65.6 %     66.8 %

Specified items*

     1.0 %     0.4 %     1.7 %     0.7 %     0.9 %
                                        

Gross Margin Excluding Specified Items

     69.4 %     68.2 %     66.4 %     66.3 %     67.7 %
                                        

 

     2005  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Net Sales

   $ 4,532     $ 4,889     $ 4,767     $ 5,019     $ 19,207  
                                        

Gross Profit

          

Gross Profit

   $ 3,165     $ 3,406     $ 3,284     $ 3,424     $ 13,279  

Specified items*

     13       21       35       33       102  
                                        

Gross Margin Excluding Specified Items

   $ 3,178     $ 3,427     $ 3,319     $ 3,457     $ 13,381  
                                        

Gross Margin %

          

Gross Margin %

     69.8 %     69.7 %     68.9 %     68.2 %     69.1 %

Specified items*

     0.3 %     0.4 %     0.7 %     0.7 %     0.5 %
                                        

Gross Margin Excluding Specified Items

     70.1 %     70.1 %     69.6 %     68.9 %     69.6 %
                                        

* Please refer to the Specified Item - QTD and YTD tabs for detail of specified items.


BRISTOL-MYERS SQUIBB COMPANY

RESEARCH AND DEVELOPMENT EXPENSES

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2006
   Q1    Q2    Q3    Q4    TOTAL YEAR

Research and Development Expenses

   $ 750    $ 740    $ 756    $ 821    $ 3,067

Specified items*

     18      1      17      49      85
                                  

Research and Development Expenses Excluding Specified Items

   $ 732    $ 739    $ 739    $ 772    $ 2,982
                                  

 

     2005
   Q1    Q2    Q3    Q4    TOTAL YEAR

Research and Development Expenses

   $ 653    $ 649    $ 669    $ 775    $ 2,746

Specified items*

     36      1      —        35      72
                                  

Research and Development Expenses Excluding Specified Items

   $ 617    $ 648    $ 669    $ 740    $ 2,674
                                  

* Please refer to the Specified Item - QTD and YTD tabs for detail of specified items.


BRISTOL-MYERS SQUIBB COMPANY

EFFECTIVE TAX RATE

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Provision for Income Taxes

          

Provision/(Benefit) for Income Taxes

   $ 328     $ 256     $ 193     $ (167 )   $ 610  

Specified items*

     (49 )     (3 )     (34 )     196       110  
                                        

Provision for Income Taxes Excluding Specified Items

   $ 279     $ 253     $ 159     $ 29     $ 720  
                                        

Earnings/(Loss) from Continuing Operations Before Minority Interest and Provision for Income Taxes

   $ 1,193     $ 1,110     $ 617     $ (285 )   $ 2,635  

Earnings from Continuing Operations Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,081     $ 1,120     $ 670     $ 425     $ 3,296  

Effective Tax Rate

          

Effective Tax Rate from Continuing Operations

     27.5 %     23.1 %     31.3 %     58.6 %     23.1 %

Effective Tax Rate from Continuing Operations Excluding Specified Items

     25.8 %     22.6 %     23.7 %     6.8 %     21.8 %

 

     2005  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Provision for Income Taxes

          

Provision/(Benefit) for Income Taxes

   $ 268     $ (21 )   $ 507     $ 178     $ 932  

Specified items*

     42       117       (202 )     52       9  
                                        

Provision for Income Taxes Excluding Specified Items

   $ 310     $ 96     $ 305     $ 230     $ 941  
                                        

Earnings from Continuing Operations Before Minority Interest and Provision for Income Taxes

   $ 928     $ 1,130     $ 1,626     $ 832     $ 4,516  

Earnings from Continuing Operations Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,102     $ 1,189     $ 1,062     $ 986     $ 4,339  

Effective Tax Rate

          

Effective Tax Rate from Continuing Operations

     28.9 %     -1.9 %     31.2 %     21.4 %     20.6 %

Effective Tax Rate from Continuing Operations Excluding Specified Items

     28.1 %     8.1 %     28.7 %     23.3 %     21.7 %

* Please refer to the Specified Item - QTD and YTD tabs for detail of specified items.


BRISTOL-MYERS SQUIBB COMPANY

EARNINGS FROM CONTINUING OPERATIONS BEFORE MINORITY INTEREST AND INCOME TAXES

EXCLUDING SPECIFIED ITEMS

($ in millions)

 

     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Earnings / (Loss) from Continuing Operations Before Minority Interest and Provision for Income Taxes

   $ 1,193     $ 1,110     $ 617     ($ 285 )   $ 2,635  

Specified items:

          

Gain on sale of product asset

     (200 )     —         —         —         (200 )

Litigation matters

     40       (14 )     (29 )     353       350  

Insurance recoveries

     (21 )     —         (9 )     (7 )     (37 )

Downsizing and streamlining of worldwide operations / other

     69       24       91       131       315  

Debt retirement costs

           220       220  

Claim for damages

     —         —         —         13       13  
                                        

Subtotal

     (112 )     10       53       710       661  
                                        

Earnings from Continuing Operations Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,081     $ 1,120     $ 670     $ 425     $ 3,296  
                                        

 

     2005  
     Q1     Q2     Q3     Q4     TOTAL YEAR  

Earnings from Continuing Operations Before Minority Interest and Provision for Income Taxes

   $ 928     $ 1,130     $ 1,626     $ 832     $ 4,516  

Specified items:

          

Gain on sale of equity investment

     (18 )     (9 )     —         —         (27 )

Litigation matters

     124       269       —         197       590  

Insurance recoveries

     —         (295 )     (26 )     —         (321 )

Provision for restructuring / other

     68       94       31       95       288  

Termination of muraglitizar agreement

     —         —         —         (138 )     (138 )

Gain on sale of businesses

     —         —         (569 )     —         (569 )
                                        

Subtotal

     174       59       (564 )     154       (177 )
                                        

Earnings from Continuing Operations Before Minority Interest and Provision for Income Taxes Excluding Specified Items

   $ 1,102     $ 1,189     $ 1,062     $ 986     $ 4,339  
                                        


BRISTOL-MYERS SQUIBB COMPANY

DILUTED EARNINGS PER COMMON SHARE FROM CONTINUING OPERATIONS

EXCLUDING SPECIFIED ITEMS

 

     2006  
     Q1     Q2     Q3     Q4     TOTAL YEAR *  

Diluted Earnings / (Loss) per Common Share from Continuing Operations

   $ 0.36     $ 0.34     $ 0.17     $ (0.07 )   $ 0.81  

Specified items:

          

Gain on sale of product asset

     (0.06 )     —         —         —         (0.06 )

Litigation matters

     0.01       —         (0.01 )     0.14       0.14  

Insurance recoveries

     (0.01 )     —         —         —         (0.01 )

Downsizing and streamlining of worldwide operations / other

     0.02       0.01       0.04       0.05       0.12  

Debt retirement costs

     —         —         —         0.07       0.07  

Tax item

     —         —         0.02       —         0.02  
                                        

Subtotal

     (0.04 )     0.01       0.05       0.26       0.28  
                                        

Diluted Earnings per Common Share from Continuing Operations Excluding Specified Items

   $ 0.32     $ 0.35     $ 0.22     $ 0.19     $ 1.09  
                                        
     2005  
     Q1     Q2     Q3     Q4     TOTAL YEAR *  

Diluted Earnings per Common Share from Continuing Operations

   $ 0.27     $ 0.50     $ 0.49     $ 0.26     $ 1.52  

Specified items:

          

Gain on sale of equity investment

     (0.01 )     —         —         —         (0.01 )

Litigation matters

     0.05       0.10       —         0.06       0.22  

Insurance recoveries

     —         (0.09 )     (0.01 )     —         (0.10 )

Provision for restructuring / other

     0.03       0.03       0.02       0.03       0.10  

Termination of muraglitizar agreement

     —         —         —         (0.04 )     (0.04 )

Gain on sale of businesses

     —         —         (0.19 )     —         (0.19 )

Tax items

     —         (0.07 )     —         —         (0.07 )
                                        

Subtotal

     0.07       (0.03 )     (0.18 )     0.05       (0.09 )
                                        

Diluted Earnings per Common Share from Continuing Operations Excluding Specified Items

   $ 0.34     $ 0.47     $ 0.31     $ 0.31     $ 1.43  
                                        

* quarterly amounts may not add to the annual total due to rounding of individual calculations.


BRISTOL-MYERS SQUIBB COMPANY

SPECIFIED ITEMS

FOR THE THREE MONTHS ENDED DECEMBER 31, 2006 AND 2005

($ in millions)

Three months ended December 31, 2006

 

     Cost of
products sold
   Research and
development
   Provision for
restructuring, net
   Litigation
settlement
(income)/
expense, net
    Other expense    Total  

Litigation Matters:

                

Pharmaceutical pricing and sales litigation

   $ —      $ —      $ —      $ 353     $ —      $ 353  

Claim for damages

     —        —        —        —         13      13  

Insurance recovery

     —        —        —        (7 )     —        (7 )
                                            
     —        —        —        346       13      359  

Other:

                

Debt retirement costs

     —        —        —        —         220      220  

Downsizing and streamlining of worldwide operations

     —        —        53      —         —        53  

Accelerated depreciation and asset impairment

     29      14      —        —         —        43  

Milestone payments

     —        35      —        —         —        35  
                                            
   $ 29    $ 49    $ 53    $ 346     $ 233      710  
                                      

Income taxes on items above

                   (196 )
                      

Reduction to Net Earnings from Continuing Operations

                 $ 514  
                      

Three months ended December 31, 2005

 

     Cost of
products sold
   Research and
development
  

Provision for

restructuring and

other items, net

   Litigation
settlement
expense
   Other income     Total  

Litigation Matters:

                

Private litigation and governmental investigations

   $ —      $ —      $ —      $ 185    $ —       $ 185  

Pharmaceutical pricing and sales litigation

     —        —        —        12      —         12  
                                            
     —        —        —        197      —         197  

Other:

                

Downsizing and streamlining of worldwide operations

     1      14      32      —        —         47  

Accelerated depreciation and asset impairment

     27      12      —        —        —         39  

Upfront and milestone payments

     —        9      —        —        —         9  

Termination of muraglitazar agreement

     5      —        —        —        (143 )     (138 )
                                            
   $ 33    $ 35    $ 32    $ 197    $ (143 )     154  
                                      

Income taxes on items above

                   (52 )
                      

Reduction to Net Earnings from Continuing Operations

                 $ 102  
                      


BRISTOL-MYERS SQUIBB COMPANY

SPECIFIED ITEMS

FOR THE TWELVE MONTHS ENDED DECEMBER 31, 2006 AND 2005

($ in millions)

Twelve months ended December 31, 2006

 

     Cost of
products
sold
  Research and
development
  Marketing, selling
and administrative
  Provision for
restructuring, net
 

Litigation
settlement

(income)/

expense, net

    Other expense   Gain on sale
of product
asset
    Total  

Litigation Matters:

               

Pharmaceutical pricing and sales litigation

  $ —     $ —     $ —     $ —     $ 353     $ —     $ —       $ 353  

Product liability

    —       —       —       —       —         11     —         11  

Claim for damages

    —       —       —       —       —         13     —         13  

Commercial litigations

    —       —       —       —       (14 )     —       —         (14 )

Insurance recovery

    —       —       —       —       (37 )     —       —         (37 )
                                                     
    —       —       —       —       302       24     —         326  

Other:

               

Debt retirement costs

    —       —       —       —       —         220     —         220  

Accelerated depreciation, asset impairment and contract termination

    167     15     4     —       —         —       —         186  

Upfront and milestone payments

    —       70     —       —       —         —       —         70  

Downsizing and streamlining of worldwide operations

    —       —       —       59     —         —       —         59  

Gain on sale of product asset

    —       —       —       —       —         —       (200 )     (200 )
                                                     
  $ 167   $ 85   $ 4   $ 59   $ 302     $ 244   $ (200 )     661  
                                               

Income taxes on items above

                  (149 )

Change in estimate for taxes on prior year items

                  39  
                     

Reduction to Net Earnings from Continuing Operations

                $ 551  
                     

Twelve months ended December 31, 2005

 

      Cost of
products
sold
   Research and
development
   Provision for
restructuring, net
   Gain
on sale of
business
    Litigation
settlement
expense/
(income), net
    Other (income)/
expense, net
    Total  

Litigation Matters:

                 

Private litigations and governmental investigations

   $ —      $ —      $ —      $ —       $ 558     $ —       $ 558  

ERISA liability and other matters

     —        —        —        —         20       —         20  

Pharmaceutical pricing and sales litigation

     —        —        —        —         12       —         12  

Insurance recoveries

     —        —        —        —         (321 )     —         (321 )
                                                     
     —        —        —        —         269       —         269  

Other:

                 

Accelerated depreciation and asset impairment

     96      14      —        —         —         —         110  

Debt retirement costs

     —        —        —        —         —         69       69  

Downsizing and streamlining of worldwide operations

     1      14      32      —         —         —         47  

Upfront and milestone payments

     —        44      —        —         —         —         44  

Loss on sale of fixed assets

     —        —        —        —         —         18       18  

Gain on sale of equity investment

     —        —        —        —         —         (27 )     (27 )

Termination of muraglitazar agreement

     5      —        —        —         —         (143 )     (138 )

Gain on sale of Consumer Medicines businesses

     —        —        —        (569 )     —         —         (569 )
                                                     
   $ 102    $ 72    $ 32    $ (569 )   $ 269     $ (83 )     (177 )
                                               

Income taxes on items above

                    126  

Adjustment to taxes on repatriation of foreign earnings

                    (135 )
                       

Increase to Net Earnings from Continuing Operations

                  $ (186 )
                       


BRISTOL-MYERS SQUIBB COMPANY

SELECT BALANCE SHEET INFORMATION

($ in millions)

 

     March 31,
2005
   June 30,
2005
   September 30,
2005
   December 31,
2005
   March 31,
2006
   June 30,
2006
   September 30,
2006
   December 31,
2006
 

Cash, cash equivalents and marketable debt securities

   $ 5,982    $ 3,040    $ 3,781    $ 5,799    $ 5,281    $ 5,357    $ 5,505    $ 4,013  

Short-term borrowings

     244      292      277      231      234      189      630      187  

Long-term debt

     8,326      6,008      5,895      8,364      8,278      8,239      7,837      7,275  
                                                         

Net debt

   $ 2,588    $ 3,260    $ 2,391    $ 2,796    $ 3,231    $ 3,071    $ 2,962    $ 3,449  
                                                         

Receivables, net of allowances

   $ 3,647    $ 3,315    $ 3,305    $ 3,378    $ 3,236    $ 3,326    $ 2,945    $ 3,247  

Stockholders’ equity

     10,381      10,801      11,268      11,208      11,556      11,712      11,589      9,991 (1)

Capital expenditures and capitalized software (for the quarter ended)

     181      171      185      201      202      160      199      224  
                                                         

(1) Includes the impact of the adoption of SFAS 158, “Employers’ Accounting for Defined Benefit Pension and Other Postretirement Plans - an amendment of FASB Statements No. 87, 88, 106 and 132(R)”


BRISTOL-MYERS SQUIBB COMPANY

2007 FULL YEAR PROJECTED DILUTED EPS FROM CONTINUING OPERATIONS

EXCLUDING PROJECTED SPECIFIED ITEMS

 

     Full Year 2007

Projected Diluted Earnings per Common Share from Continuing Operations

   $ 1.12 to $1.22

Projected Specified Items:

  

Upfront and milestone payments

     0.05

Downsizing and streamlining of worldwide operations

     0.03
      

Total

     0.08
      

Projected Diluted Earnings per Common Share from Continuing Operations Excluding Specified Items

   $ 1.20 to $1.30
      

Gross Margin/Tax Rate Projections Excluding Specified Items

Gross margin on a GAAP basis for the full year 2006 was 66.8%, which included specified items of $167 million and had a 0.9% adverse impact on gross margin in aggregate. On a non-GAAP basis, 2006 gross margin was 67.7%. On a non-GAAP basis, based on historical trends in 2006 the Company projects gross margin for the full year 2007 to be at least 100 basis points higher than 2006. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on gross margin. See Gross Margin non comparable tab.

Research and development expenses on a GAAP basis for the full year 2006 were $3,067 million, which included specified items of $85 million. On a non-GAAP basis, 2006 research and development expenses were $2,982 million. On a non-GAAP basis, based on historical trends in 2006 the Company projects research and development expenses for the full year 2007 to increase in the upper single digit range compared to 2006. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on research and development. See R&D non comparable tab.

The effective tax rate on a GAAP basis in 2006 was 23.1%, which included specified items of $110 million, and had a 1.3% adverse impact on the effective tax rate in aggregate. On a non-GAAP basis, 2006 effective tax rate was 21.8%. On a non-GAAP basis, based on historical trends in 2006 the Company projects effective tax rate for the full year 2007 to be in line with the 2006 rate. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on the tax rate. See Tax Rate non comparable tab.

The GAAP results for the full year 2007 would include specified items that may occur and impact results. These specified items could include charges and recoveries relating to significant legal proceedings, debt retirement costs and other charges related to new transactions, milestone payments, copromotion or alliance charges and charges for in-process research and development related to new external development transactions, gains or losses from asset disposals and restructuring activities. For a fuller discussion of certain of the litigation and other matters that could impact full year GAAP results, as well as the use of non-GAAP financial information, see Bristol-Myers Squibb Company Reports Financial Results For The Fourth Quarter and Twelve Months of 2006, January 25, 2007, including “2007 Guidance” and “Use of Non-GAAP Financial Information” therein.


BRISTOL-MYERS SQUIBB COMPANY

ESTIMATED MONTHS ON HAND OF TOP 15 U.S. PHARMACEUTICAL PRODUCTS

IN THE U.S. WHOLESALER DISTRIBUTION CHANNEL

The following table sets forth, for each of the Company’s top 15 pharmaceutical products (based on 2005 annual net sales) and other products that the Company views as current and future growth drivers sold by the Company’s U.S. Pharmaceuticals business, the U.S. Pharmaceuticals net sales and the estimated number of months on hand of the applicable product in the U.S. wholesaler distribution channel for the quarters ended December 31, 2006 and 2005 and September 30, 2006 and 2005.

 

     December 31, 2006    September 30, 2006    December 31, 2005    September 30, 2005
   Net Sales     Months on Hand    Net Sales    Months on Hand    Net Sales    Months on Hand    Net Sales    Months on Hand
   (Dollars in Millions)          (Dollars in Millions)         (Dollars in Millions)         (Dollars in Millions)     

Abilify (total revenue)

   $ 294     0.5    $ 260    0.5    $ 175    0.6    $ 214    0.9

Avapro/Avalide

     182     0.5      159    0.4      168    0.6      147    0.5

Baraclude

     18     0.7      14    0.6      4    0.7      2    1.2

Cefzil

     (5 )   21.7      1    29.2      46    0.7      27    0.7

Coumadin

     48     0.8      45    0.7      50    0.8      49    0.6

Erbitux*

     165     0.4      173    0.5      121    —        106    —  

Glucophage Franchise

     16     0.7      20    0.7      29    0.7      38    0.7

Kenalog

     24     0.8      19    0.8      23    0.9      19    0.7

Orencia**

     31     0.4      34    0.8      —      —        —      —  

Paraplatin

     6     5.8      5    1.5      5    0.9      9    1.1

Plavix

     343     0.6      474    1.5      906    0.6      833    0.4

Pravachol

     50     0.6      73    1.0      366    0.6      297    0.5

Reyataz

     144     0.7      129    0.5      110    0.5      105    0.6

Sprycel

     11     1.4      11    1.2      —      —        —      —  

Sustiva Franchise (a) (total revenue)

     144     0.7      128    0.5      102    0.6      101    0.6

Tequin

     (10 )   —        2    2.3      22    0.9      21    0.9

Videx/Videx EC

     2     1.1      3    0.9      7    0.9      7    1.1

Zerit

     19     0.9      19    0.7      21    0.8      24    0.8

For all products other than Erbitux and Orencia, the Company determines the above months on hand estimates by dividing the estimated amount of the product in the U.S. wholesaler distribution channel by the estimated amount of out-movement of the product from the U.S. wholesaler distribution channel over a period of 31 days, all calculated as described below. Factors that may influence the Company’s estimates include generic competition, seasonality of products, wholesaler purchases in light of increases in wholesaler list prices, new product launches, new warehouse openings by wholesalers and new customer stockings by wholesalers. In addition, such estimates are calculated using third party data, which represent their own record-keeping processes and as such, may also reflect estimates.

Estimates of product in the wholesaler distribution channel and out-movement are based on weekly information received directly from third-parties, and excludes any inventory held by intermediaries such as retailers and hospitals, and excludes goods in transit to such wholesalers. The Company determines the amount of out-movement of a product over a period of 31 days by using the most recent out-movement of a product as provided by these third parties, adjusted to reflect the Company’s estimate of goods in transit to these wholesalers. The Company estimates the amount of goods in transit by using information provided by these wholesalers with respect to their open orders and the Company’s records of sales to these wholesalers with respect to such open orders.


* To help maintain the product quality of the Company’s biologic oncology product, Erbitux, the product was previously shipped only to end-users and not to other intermediaries (such as wholesalers) to hold for later sales. During 2004 and through May 2005, one of the Company’s wholesalers provided warehousing, packing and shipping services for Erbitux. Such wholesaler held Erbitux inventory on consignment and, under the Company’s revenue recognition policy, the Company recognized revenue when such inventory was shipped by the wholesaler to the end-user.  Upon the divestiture of OTN in May 2005, the Company discontinued the consignment arrangement with the wholesaler and thereafter did not have Erbitux consignment inventory.  Following the divestiture, the Company sold Erbitux to intermediaries (such as specialty oncology distributors) and shipped Erbitux directly to the end-users of the product who are the customers of those intermediaries.  Beginning in the third quarter 2006, the Company expanded its distribution model to one of the Company’s wholesalers who then held Erbitux inventory beginning with the quarter ended September 30, 2006.  The Company recognizes revenue upon such shipment consistent with its revenue recognition policy.  The above estimate of months on hand was calculated by dividing the inventories of Erbitux held by the wholesaler for its own account as reported by the wholesaler as of the end of the quarter by the outmovements of the product reported by that wholesaler over the last 31 day period, not the Company’s net sales for the last calendar month of the quarter. The inventory levels reported by the wholesaler are a product of the wholesaler’s own record-keeping process.

 

** Orencia was launched in February 2006. From launch through the second quarter, the Company distributed Orencia through an exclusive distribution arrangement with a single distributor. Following approval of the supplemental Biologics License Application (sBLA) that allows a third party to manufacture Orencia at an additional site, that arrangement recently terminated and the Company expanded its distribution network for Orencia to multiple distributors. The above estimates of months on hand were calculated by dividing the inventories of Orencia held by these distributors at the end of the quarter by the outmovement of the product over the last 31 day period, as reported by these distributors. The inventory on hand and outmovements reported by these distributors are a product of the distributors’ own record-keeping process.

 

(a) Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. The estimated months on hand of the product in the U.S. wholesale distribution channel only include branded Sustiva inventory.


BRISTOL-MYERS SQUIBB COMPANY

ESTIMATED MONTHS ON HAND OF TOP INTERNATIONAL PHARMACEUTICAL

AND WORLDWIDE NON-PHARMACEUTICAL PRODUCTS

The following table, which was posted on the Company’s website and furnished on Form 8-K on November 30, 2006, sets forth for each of the Company’s key products sold by the reporting segments listed below, the net sales of the applicable product for each of the quarters ended September 30, 2006 and 2005 and June 30, 2006 and 2005, and the estimated number of months on hand of the applicable product in the direct customer distribution channel for the reporting segment as of the end of each of the four quarters. The estimates of months on hand for key products described below for the International Pharmaceuticals reporting segment are based on data collected for all of the Company’s significant business units outside of the United States. For the other reporting segments, estimates are based on data collected for the United States and all significant business units outside of the United States.

 

     September 30, 2006    June 30, 2006    September 30, 2005    June 30, 2005
     Net Sales    Months on Hand    Net Sales    Months on Hand    Net Sales    Months on Hand    Net Sales    Months on Hand
     (Dollars in Millions)         (Dollars in Millions)         (Dollars in Millions)         (Dollars in Millions)     

International Pharmaceuticals

                       

Abilify (total revenue)

   $ 53    0.6    $ 57    0.6    $ 46    0.8    $ 40    0.6

Avapro/Avalide

     118    0.5      113    0.5      104    0.5      101    0.4

Baraclude

     8    0.9      5    1.0      —      —        —      —  

Bufferin

     28    0.5      31    0.5      31    0.6      32    1.0

Capoten

     28    0.8      31    0.9      38    0.9      42    0.8

Dafalgan

     35    1.1      37    1.1      34    1.3      33    0.8

Efferalgan

     62    0.9      62    0.9      66    1.1      55    0.5

Maxipime

     40    0.7      43    0.8      40    0.7      52    0.8

Monopril

     34    1.0      48    1.1      48    1.0      52    0.7

Paraplatin

     27    0.6      29    0.6      33    0.6      34    0.6

Perfalgan

     48    0.6      51    0.6      38    0.7      42    0.6

Plavix

     156    0.6      157    0.5      147    0.6      145    0.5

Pravachol

     119    0.7      195    1.4      230    0.8      272    0.7

Reyataz

     104    1.1      114    0.7      71    0.9      85    0.8

Sustiva

     73    0.5      78    0.5      69    0.6      70    0.6

Taxol

     135    0.6      145    0.5      171    0.5      182    0.5

Videx/Videx EC

     35    1.4      35    1.2      34    0.9      38    0.9

Nutritionals

                       

Enfamil/Enfagrow

     315    0.8      312    0.9      284    0.9      299    0.9

Nutramigen

     50    1.0      54    1.0      44    1.1      47    1.0

Other Health Care

                       

ConvaTec

                       

Ostomy

     139    0.9      141    1.0      139    0.9      139    0.9

Wound Therapeutics

     113    0.9      107    0.9      104    0.8      103    0.8

Medical Imaging

                       

Cardiolite

     97    0.8      105    0.8      106    0.8      108    0.7

The above months on hand information represents the Company’s estimates of aggregate product level inventory on hand at direct customers divided by the expected demand for the applicable product. Expected demand is the estimated ultimate patient/consumer demand calculated based on estimated end-user consumption or direct customer out-movement data over the most recent 31 day period or other reasonable period. Factors that may affect the Company’s estimates include generic competition, seasonality of products, direct customer purchases in light of price increases, new product or product presentation launches, new warehouse openings by direct customers, new customer stockings by direct customers and expected direct customer purchases for governmental bidding situations.

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-----END PRIVACY-ENHANCED MESSAGE-----