INCOME TAXES - Schedule of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Millions	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets
Foreign net operating loss carryforwards	$ 945	$ 3,271
State net operating loss and credit carryforwards	304	325
U.S. Federal net operating loss and credit carryforwards	226	435
Milestone payments and license fees	887	643
Other foreign deferred tax assets	237	307
Share-based compensation	232	389
Other	921	981
Total deferred tax assets	3,752	6,351
Valuation allowance	(1,056)	(2,809)
Deferred tax assets net of valuation allowance	2,696	3,542
Deferred tax liabilities
Acquired intangible assets	(4,867)	(6,612)
Goodwill and other	(891)	(1,176)
Total deferred tax liabilities	(5,758)	(7,788)
Deferred tax liabilities, net	(3,062)	(4,246)
Deferred income taxes assets – non-current	1,439	1,161
Deferred income taxes liabilities – non-current	$ (4,501)	$ (5,407)