INCOME TAXES - Additional Information (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Valuation Allowance [Line Items]
Global intangible low taxed income (GILTI)	$ 687	$ 729	$ 849
Unrecognized tax benefits, reduction resulting from lapse of applicable statute of limitations, including interest accrued			81
Asset acquisition charges	1,157	1,099	63
Valuation allowance	1,056	2,809
Income tax payments	3,500	3,400	1,500
Transition tax due 2022	339
Transition tax due 2023	567
Transition tax due 2024	799
Transition tax due 2025	1,000
Transition tax due 2026	244
MyoKardia Acquisition
Valuation Allowance [Line Items]
Asset acquisition charges		11,400
Foreign Net Operating Loss And Tax Credit Carryforwards
Valuation Allowance [Line Items]
Valuation allowance	583
State Net Operating Loss And Tax Credit Carryforwards
Valuation Allowance [Line Items]
Valuation allowance	183
SEC Schedule, 12-09, Valuation Allowance, Other Tax Carryforward
Valuation Allowance [Line Items]
Valuation allowance	290
Domestic Tax Authority
Valuation Allowance [Line Items]
Operating loss carryforwards	585
Minimum
Valuation Allowance [Line Items]
Reasonably possible decrease in unrecognized tax benefits	395
Maximum
Valuation Allowance [Line Items]
Reasonably possible decrease in unrecognized tax benefits	$ 445
Otezla
Valuation Allowance [Line Items]
Global intangible low taxed income (GILTI)		$ 266	$ 808