INCOME TAXES - Schedule of Effective Income Tax Rate Reconciliation (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Earnings/(Loss) before income taxes:
U.S.	$ 1,593	$ (10,106)	$ 542
Non-U.S.	6,505	3,235	4,433
Earnings/(Loss) Before Income Taxes	8,098	(6,871)	4,975
Effective Income Tax Rate Reconciliation, Amount
U.S. statutory rate	1,701	(1,443)	1,045
Global intangible low taxed income (GILTI)	687	729	849
Foreign tax effect of certain operations in Ireland, Puerto Rico and Switzerland	(143)	(86)	(68)
Internal transfers of intangible assets	(983)	853	0
U.S. Federal, state and foreign contingent tax matters	154	136	(13)
U.S. Federal research based credits	(165)	(165)	(138)
Contingent value rights	(108)	(363)	110
Non-deductible R&D charges	0	2,461	5
Puerto Rico excise tax	(152)	(147)	(163)
State and local taxes (net of valuation allowance)	33	103	(16)
Foreign and other	60	46	(96)
Total Provision	$ 1,084	$ 2,124	$ 1,515
Effective Income Tax Rate Reconciliation, Percent
U.S. statutory rate	21.00%	21.00%	21.00%
Global intangible low taxed income (GILTI)	8.50%	(10.60%)	17.10%
Foreign tax effect of certain operations in Ireland, Puerto Rico and Switzerland	(1.80%)	1.30%	(1.40%)
Internal transfers of intangible assets	(12.10%)	(12.40%)	0.00%
U.S. Federal, state and foreign contingent tax matters	1.90%	(2.00%)	(0.30%)
U.S. Federal research based credits	(2.00%)	2.40%	(2.80%)
Contingent value rights	(1.30%)	5.30%	2.20%
Non-deductible R&D charges	0.00%	(35.80%)	0.10%
Puerto Rico excise tax	(1.90%)	2.10%	(3.30%)
State and local taxes (net of valuation allowance)	0.40%	(1.50%)	(0.30%)
Foreign and other	0.70%	(0.70%)	(1.80%)
Total	13.40%	(30.90%)	30.50%