RESTRUCTURING - Schedule of Restructuring and Related Costs (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Restructuring Cost and Reserve [Line Items]
Total charges	$ 751	$ 1,410	$ 979
Employee termination costs	159	457	273
Other termination costs	10	73	28
Provision for restructuring	169	530	301
Integration expenses	564	717	415
Accelerated depreciation	2	53	133
Asset impairments	24	103	130
Other shutdown costs, net	(8)	7	0
Cost of products sold
Restructuring Cost and Reserve [Line Items]
Total charges	24	32	180
Marketing, selling and administrative
Restructuring Cost and Reserve [Line Items]
Total charges	3	10	1
Research and development
Restructuring Cost and Reserve [Line Items]
Total charges	0	113	82
Other (income)/expense, net
Restructuring Cost and Reserve [Line Items]
Total charges	724	1,255	716
Celgene Acquisition Plan
Restructuring Cost and Reserve [Line Items]
Total charges	673	1,244	674
MyoKardia Acquisition Plan
Restructuring Cost and Reserve [Line Items]
Total charges	78	39	0
Company Transformation
Restructuring Cost and Reserve [Line Items]
Total charges	$ 0	$ 127	$ 305