ACQUISITIONS, DIVESTITURES, LICENSING AND OTHER ARRANGEMENTS - Divestitures (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Divestiture proceeds	$ 748	$ 715	$ 15,642
Divestiture (Gains)/Losses	9	55	1,168
Royalty Income	(666)	(644)	(686)
Diabetes Business
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Divestiture proceeds	612	558	661
Divestiture (Gains)/Losses	0	0	0
Royalty Income	(622)	(567)	(650)
Otezla
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Divestiture proceeds	0	0	13,400
Divestiture (Gains)/Losses	0	0	0
Royalty Income	0	0	0
UPSA Business
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Divestiture proceeds	0	0	1,508
Divestiture (Gains)/Losses	0	0	(1,157)
Royalty Income	0	0	0
Mature Brands and Other
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Divestiture proceeds	136	157	73
Divestiture (Gains)/Losses	(9)	(55)	(11)
Royalty Income	(44)	(77)	(36)
Not all inclusive
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Divestiture (Gains)/Losses	$ (9)	$ (55)	$ (1,168)