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ALLIANCES - Financial Information Pertaining to Alliances (Ono) (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total Revenues $ 46,385 $ 42,518 $ 26,145
Collaborative Arrangement      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total Revenues $ 11,556 9,979 10,541
Collaborative Arrangement | Ono      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Co-promotion fee percentage 60.00%    
Total Revenues $ 636 576 499
Collaborative Arrangement | Ono | Maximum      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Profit sharing involving only one compound 80.00%    
Collaborative Arrangement | Ono | Minimum      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Profit sharing involving only one compound 20.00%    
Collaborative Arrangement | North America | Ono      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Royalty rate due to regulatory approvals 4.00%    
Collaborative Arrangement | Rest of World Except Japan, South Korea and Taiwan | Ono      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Royalty rate due to regulatory approvals 15.00%    
Net product sales      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total Revenues $ 45,055 41,321 25,174
Net product sales | Collaborative Arrangement      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total Revenues 10,840 9,364 9,944
Net product sales | Collaborative Arrangement | Ono      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total Revenues 251 194 194
Collaborative Arrangement | Collaborative Arrangement      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total Revenues 716 615 597
Collaborative Arrangement | Collaborative Arrangement | Ono      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Total Revenues $ 385 $ 382 $ 305