ALLIANCES - Financial Information Pertaining to Alliances (Total) (Details) - USD ($) $ in Millions		12 Months Ended
		Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total Revenues		$ 46,385	$ 42,518	$ 26,145
Cost of products sold	[1]	9,940	11,773	8,078
Other (income)/expense, net		(720)	(2,314)	938
Receivables – from alliance partners		9,369	8,501
Accounts payable – to alliance partners		2,949	2,713
Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total Revenues		11,556	9,979	10,541
Cost of products sold		5,227	4,485	4,169
Marketing, selling and administrative		(183)	(128)	(127)
Research and development		772	349	42
Other (income)/expense, net		(62)	(74)	(60)
Receivables – from alliance partners		320	343
Accounts payable – to alliance partners		1,229	1,093
Deferred income from alliances		330	366
Net product sales
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total Revenues		45,055	41,321	25,174
Net product sales | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total Revenues		10,840	9,364	9,944
Collaborative Arrangement | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total Revenues		$ 716	$ 615	$ 597

[1] Excludes amortization of acquired intangible assets.