EMPLOYEE STOCK BENEFIT PLANS - Summary of Stock Compensation Activity (Details) - USD ($) $ / shares in Units, shares in Millions, $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Weighted-average exercise price per stock
Total intrinsic value of stock options exercised	$ 512	$ 556	$ 148
Stock Options
Stock compensation activity, shares
Stock options, beginning balance (in shares)	73.4
Stock options, granted (in shares)	0.0
Stock options, released/exercised (in shares)	(23.1)
Stock options, adjustments for actual payout (in shares)	0.0
Stock options, forfeited/canceled (in shares)	(3.3)
Stock options, ending balance (in shares)	47.0	73.4
Weighted-average exercise price per stock
Stock options, weighted-average exercise price at the beginning of the period (in dollars per share)	$ 50.25
Stock options, granted, weighted-average exercise price at the beginning of the period (in dollars per share)	0
Stock options, released/exercised, weighted-average exercise price at the beginning of the period (in dollars per share)	42.70
Stock options, adjustments for actual payout, weighted-average exercise price at the beginning of the period (in dollars per share)	0
Stock options, forfeited/canceled, weighted-average exercise price at the beginning of the period (in dollars per share)	63.71
Stock options, weighted-average exercise price at the end of the period (in dollars per share)	53.00	$ 50.25
Other than options, granted, weighted average grant date fair value (in usd per share)	$ 0	$ 0	$ 15.00
Options nonvested (in shares)	2.0
Options nonvested, weighted average exercise price (in usd per share)	$ 48.22
Unrecognized compensation cost	$ 7
Expected weighted-average period in years of compensation cost to be recognized	7 months 6 days
Restricted Stock Units
Stock compensation activity, shares
Other than options, beginning balance (in shares)	27.7
Other than options, granted (in shares)	8.9
Other than options, released/exercised (in shares)	(13.8)
Other than options, adjustments for actual payout (in shares)	0.0
Other than options, forfeited/canceled (in shares)	(3.7)
Other than options, ending balance (in shares)	19.1	27.7
Weighted-average exercise price per stock
Other than options, weighted average grant date fair value at the beginning of the period (in usd per share)	$ 54.58
Other than options, granted, weighted average grant date fair value (in usd per share)	56.58	$ 53.65	$ 47.16
Other than options, released/exercised, weighted average grant date fair value (in usd per share)	55.36
Other than options, adjustments for actual payout, weighted average grant date fair value (in usd per share)	0
Other than options, forfeited/canceled, weighted average grant date fair value (in usd per share)	54.71
Other than options, weighted average grant date fair value at the end of the period (in usd per share)	$ 54.92	$ 54.58
Other than options, expected to vest (in shares)	17.0
Other than options, expected to vest, weighted average grant date fair value (in usd per share)	$ 54.91
Unrecognized compensation cost	$ 676
Expected weighted-average period in years of compensation cost to be recognized	2 years 7 months 6 days
Fair value of awards that vested during the year	$ 246	$ 122	$ 105
Restricted Stock Units | Legacy Celgene Plans
Weighted-average exercise price per stock
Other than options, granted, weighted average grant date fair value (in usd per share)	$ 0	$ 0	$ 56.37
Fair value of awards that vested during the year	$ 519	$ 777	$ 233
Market Share Units
Stock compensation activity, shares
Other than options, beginning balance (in shares)	1.7
Other than options, granted (in shares)	1.0
Other than options, released/exercised (in shares)	(0.6)
Other than options, adjustments for actual payout (in shares)	0.0
Other than options, forfeited/canceled (in shares)	(0.3)
Other than options, ending balance (in shares)	1.8	1.7
Weighted-average exercise price per stock
Other than options, weighted average grant date fair value at the beginning of the period (in usd per share)	$ 56.01
Other than options, granted, weighted average grant date fair value (in usd per share)	58.04	$ 53.92	$ 51.52
Other than options, released/exercised, weighted average grant date fair value (in usd per share)	57.25
Other than options, adjustments for actual payout, weighted average grant date fair value (in usd per share)	0
Other than options, forfeited/canceled, weighted average grant date fair value (in usd per share)	56.15
Other than options, weighted average grant date fair value at the end of the period (in usd per share)	$ 56.51	$ 56.01
Other than options, expected to vest (in shares)	1.6
Other than options, expected to vest, weighted average grant date fair value (in usd per share)	$ 56.51
Unrecognized compensation cost	$ 46
Expected weighted-average period in years of compensation cost to be recognized	2 years 9 months 18 days
Fair value of awards that vested during the year	$ 37	$ 37	$ 30
Performance Share Units
Stock compensation activity, shares
Other than options, beginning balance (in shares)	3.1
Other than options, granted (in shares)	1.5
Other than options, released/exercised (in shares)	(0.9)
Other than options, adjustments for actual payout (in shares)	0.1
Other than options, forfeited/canceled (in shares)	(0.4)
Other than options, ending balance (in shares)	3.4	3.1
Weighted-average exercise price per stock
Other than options, weighted average grant date fair value at the beginning of the period (in usd per share)	$ 56.72
Other than options, granted, weighted average grant date fair value (in usd per share)	59.04	$ 55.61	$ 49.99
Other than options, released/exercised, weighted average grant date fair value (in usd per share)	67.60
Other than options, adjustments for actual payout, weighted average grant date fair value (in usd per share)	67.60
Other than options, forfeited/canceled, weighted average grant date fair value (in usd per share)	56.04
Other than options, weighted average grant date fair value at the end of the period (in usd per share)	$ 55.38	$ 56.72
Other than options, expected to vest (in shares)	3.2
Other than options, expected to vest, weighted average grant date fair value (in usd per share)	$ 54.85
Unrecognized compensation cost	$ 83
Expected weighted-average period in years of compensation cost to be recognized	1 year 8 months 12 days
Fair value of awards that vested during the year	$ 61	$ 59	$ 53