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EMPLOYEE STOCK BENEFIT PLANS - Stock Based Compensation Expense (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Total stock-based compensation expense $ 583 $ 779 $ 441
Income tax benefit 120 158 87
Excess tax benefits from share-based compensation awards 38 35 4
Cost of products sold      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Total stock-based compensation expense 57 37 19
Marketing, selling and administrative      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Total stock-based compensation expense 241 332 162
Research and development      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Total stock-based compensation expense 272 339 115
Other (income)/expense, net      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Total stock-based compensation expense $ 13 $ 71 $ 145