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Milestones and Research Agreements - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Nov. 30, 2020
Sep. 30, 2021
Sep. 30, 2021
Dec. 31, 2020
Sep. 30, 2020
Milestone and Research Agreements:          
Potential milestone payment   $ 800,000 $ 800,000    
Performance milestone payment     0    
Accrued expenses   5,457,000 5,457,000 $ 11,987,000  
Microbiome Targeted Colonic Delivery Program          
Milestone and Research Agreements:          
Accrued expenses   0 0   $ 0
Door Pharma Agreement          
Milestone and Research Agreements:          
License agreement term 2 years        
Up-front payment $ 1,800,000        
Milestone payments   200,000      
Research and development funding charges   $ 500,000 $ 1,300,000    
Door Pharma Agreement | Maximum          
Milestone and Research Agreements:          
Success-based milestones 35,000,000.0        
Exercise and annual fees 2,000,000.0        
Door Pharma Agreement | Minimum          
Milestone and Research Agreements:          
Exercise and annual fees $ 100,000