CONDENSED CONSOLIDATED STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY - 6 months ended Jun. 30, 2018 - USD ($)	Total	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Loss [Member]	Accumulated Deficit [Member]
Balance at Dec. 31, 2017	$ 113,119,769	$ 20,138	$ 364,528,037	$ (392,391)	$ (251,036,015)
Balance (in Shares) at Dec. 31, 2017		20,137,974
Proceeds from the exercise of stock options	3,343,736	$ 476	3,343,260	0	0
Proceeds from the exercise of stock options (in shares)		476,524
Change in unrealized gain on marketable securities, net of income tax expense of $6,472	20,313	$ 0	0	20,313	0
Stock-based compensation	15,671,738	0	15,671,738	0	0
Net loss	(43,054,991)	0	0	0	(43,054,991)
Balance at Jun. 30, 2018	$ 89,100,565	$ 20,614	$ 383,543,035	$ (372,078)	$ (294,091,006)
Balance (in Shares) at Jun. 30, 2018		20,614,498