CONSOLDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)	Total	Common Stock [Member]	Preferred Stock [Member]	Additional Paid-in Capital [Member]	Common Stock Issuable [Member]	Accumulated Other Comprehensive Loss [Member]	Accumulated Deficit [Member]
Balance at Dec. 31, 2013	$ 24,493,988	$ 4,147	$ 44	$ 135,844,320	$ 368,750	$ 0	$ (111,723,273)
Balance (in shares) at Dec. 31, 2013		4,146,779	44,000
Proceeds from common stock sold, net of underwriters' discounts and cost	16,725,946	$ 2,051	$ 0	16,723,895	0	0	0
Proceeds from common stock sold, net of underwriters' discounts and cost (in Shares)		2,051,472	0
Issuance of common stock for business combination	29,064,148	$ 4,009	$ 0	29,060,139	0	0	0
Issuance of common stock for business combination (in shares)		4,008,808	0
Issuance of common stock in exchange for restricted stock units	0	$ 25	$ 0	368,725	(368,750)	0	0
Issuance of common stock in exchange for restricted stock units (in shares)		25,000	0
Conversion of preferred stock to common stock	0	$ 440	$ (44)	(396)	0	0	0
Conversion of preferred stock to common stock (in shares)		440,000	(44,000)
Fair value of options assumed	758,948	$ 0	$ 0	758,948	0	0	0
Issuance of warrants for services	679,447	0	0	679,447	0	0	0
Stock-based compensation	10,637,494	0	0	10,637,494	0	0	0
Net loss	(23,788,799)	0	0	0	0	0	(23,788,799)
Balance at Dec. 31, 2014	58,571,172	$ 10,672	$ 0	194,072,572	0	0	(135,512,072)
Balance (in shares) at Dec. 31, 2014		10,672,059	0
Proceeds from common stock sold, net of underwriters' discounts and cost	81,014,989	$ 6,389	$ 0	81,008,600	0	0	0
Proceeds from common stock sold, net of underwriters' discounts and cost (in Shares)		6,388,888	0
Exercise of stock options	554,268	$ 77	$ 0	554,191	0	0	0
Exercise of stock options (in shares)		76,422	0
Cashless exercise of warrants	0	$ 88	$ 0	(88)	0	0	0
Cashless exercise of warrants (in shares)		88,293	0
Stock-based compensation	7,876,584	$ 0	$ 0	7,876,584	0	0	0
Change in unrealized loss on marketable securities	(821,585)	0	0	0	0	(821,585)	0
Net loss	(28,453,833)	0	0	0	0	0	(28,453,833)
Balance at Dec. 31, 2015	$ 118,741,595	$ 17,226	$ 0	$ 283,511,859	$ 0	$ (821,585)	$ (163,965,905)
Balance (in shares) at Dec. 31, 2015		17,225,662	0