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Share-Based Compensation - Schedule of Stock Option Activity (Detail) - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2024
Dec. 31, 2023
Stock Option Shares    
Shares, Outstanding at beginning balance (in shares) 4,579,659  
Shares, Granted (in shares) 1,461,715  
Shares, Exercised (in shares) 0  
Shares, Expired/cancelled (in shares) (590,041)  
Shares, Outstanding at ending balance (in shares) 5,451,333 4,579,659
Shares, Options exercisable (in shares) 2,478,035  
Shares, Vested and expected (in shares) 5,451,333  
Weighted Average Exercise Price    
Outstanding at beginning balance (in dollars per share) $ 14.11  
Granted (in dollars per share) 1.87  
Exercised (in dollars per share) 0  
Expired/cancelled (in dollars per share) 11.41  
Outstanding at ending balance (in dollars per share) 11.05 $ 14.11
Weighted Average Exercise Price, Options exercisable (in dollars per share) 13.97  
Weighted Average Exercise Price, Vested and expected to vest (in dollars per share) $ 11.05  
Weighted Average Remaining Contractual Term, Outstanding 8 years 4 months 24 days 8 years 4 months 13 days
Weighted Average Remaining Contractual Term, Options exercisable 7 years 9 months 21 days  
Weighted Average Remaining Contractual Term, Vested and expected to vest 8 years 4 months 24 days  
Aggregate Intrinsic Value, Outstanding $ 16 $ 25
Aggregate Intrinsic Value, Options exercisable 16  
Aggregate Intrinsic Value, Vested and expected to vest $ 16