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Stock-Based Awards (Tables)
6 Months Ended
Jun. 30, 2017
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Valuation Assumptions of Stock Options Granted

The assumptions that the Company used to determine the grant-date fair value of the stock options granted to employees and directors during the six months ended June 30, 2017 and 2016 were as follows, presented on a weighted average basis:

 

     Six Months
Ended
June 30, 2017
    Six Months
Ended
June 30, 2016
 

Risk-free interest rate

     2.19     1.37

Expected term (in years)

     6.1       6.1  

Expected volatility

     80.2     80.5

Expected dividend yield

     0     0
Summary of Stock Option Activity

The following table summarizes the Company’s stock option activity since January 1, 2017:

 

     Number of
Shares
     Weighted
Average
Exercise
Price
     Weighted
Average
Remaining
Contractual
Term
     Aggregate
Intrinsic
Value
 
                   (in years)         

Outstanding at December 31, 2016

     920,731      $ 4.36        6.4      $ 1,297  

Granted

     588,701        8.08        

Exercised

     (18,524      4.33        

Forfeited

     (46,594      5.14        
  

 

 

          

Outstanding at June 30, 2017

     1,444,314      $ 5.85        7.7      $ 8,220  
  

 

 

          

Options exercisable at June 30, 2017

     636,409      $ 4.00        5.8      $ 4,550  

Options vested and expected to vest at June 30, 2017

     1,408,747      $ 5.81        7.6      $ 8,063  

Options exercisable at December 31, 2016

     585,959      $ 3.78        5.2      $ 1,136  

Options vested and expected to vest at December 31, 2016

     904,010      $ 4.37        6.3      $ 1,289  

Summary of Stock Based Compensation Expense

The Company recorded stock-based compensation expense related to stock options in the following expense categories of its statements of operations and comprehensive loss:

 

     Three Months Ended June 30,      Six Months Ended June 30,  
     2017      2016      2017      2016  

Research and development expenses

   $ 131      $ 53      $ 205      $ 104  

General and administrative expenses

     142        114        264        226  
  

 

 

    

 

 

    

 

 

    

 

 

 
   $ 273      $ 167      $ 469      $ 330