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Income taxes, Deferred Tax Assets (Details) - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Deferred tax assets [Abstract]        
Net operating loss carryforwards $ 28,047,903 $ 23,727,093    
Net operating loss carryforwards - foreign 18,649 20,227    
Excess of tax basis over book value of property and equipment 7,754 4,240    
Excess of tax basis over book value of intangible assets 1,811,264 73,705    
Stock-based compensation 1,613,258 1,607,841    
Accrued employee compensation 426,514 357,869    
Capitalized equity costs 49,471 49,471    
Net change in reserve accounts 287,035 38,323    
Gross deferred tax assets 32,261,848 25,878,769    
Valuation allowance (32,261,848) (25,878,769)    
Net deferred tax assets 0 0    
Income Tax Penalties and Interest Expense [Abstract]        
Income tax penalties 0 0    
Interest on income taxes $ 0 0    
Earliest Tax Year [Member]        
Operating Loss Carryforwards [Abstract]        
Operating loss carryforwards, expiry date Dec. 31, 2024      
Latest Tax Year [Member]        
Operating Loss Carryforwards [Abstract]        
Operating loss carryforwards, expiry date Dec. 31, 2025      
Domestic [Member]        
Operating Loss Carryforwards [Abstract]        
Net operating loss carryforwards       $ 77,900,000
Operating loss carryforwards limited with no expiration $ 36,300,000 36,300,000 $ 36,300,000  
Foreign [Member]        
Operating Loss Carryforwards [Abstract]        
Net operating loss carryforwards 100,000      
State and Local Jurisdiction [Member]        
Operating Loss Carryforwards [Abstract]        
Net operating loss carryforwards       $ 77,900,000
Operating loss carryforwards limited with no expiration $ 36,300,000 $ 36,300,000 $ 36,300,000