Income Taxes - Reconciliation of Income Tax Rate (Detail) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Effective Income Tax Rate Reconciliation, Amount
Tax at federal statutory rate	$ 3,873	$ (39,399)	$ (6,499)
State tax, net of federal tax benefit	1,524	(81)	(60)
Stock-based compensation expense	(11,839)	8,044	4,773
Research and development tax credits	(4,354)	(994)	(2,336)
Change in valuation allowance	7,867	29,728	(802)
Change in unrecognized tax benefit	2,177	497	1,168
Non-deductible expenses	742	2,278	3,250
Other	(126)	(152)	305
Income tax benefit	$ (136)	$ (79)	$ (201)

Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to increase (decrease) in the valuation allowance for deferred tax assets.

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The amount of income tax expense or benefit for the period computed by applying the domestic federal statutory tax rates to pretax income from continuing operations.

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