Exhibit 12.1

Talecris Biotherapeutics Holdings Corp.

Ratio of Earnings to Fixed Charges

(Dollars in thousands)

	Predecessor			Successor
	Three Months			Nine Months
	Ended			Ended
	March 31,			December 31,			Years Ended December 31,
	2005			2005			2006			2007			2008			2009
(Losses) earnings:
(Loss) income from continuing operations before income taxes	$	(6,500	)	$	(40,514	)	$	86,613		$	82,771		$	102,391		$	228,897
Deduct:
Earnings of equity investees	—			(197		)	(684		)	(436		)	(426		)	(441		)
Interest capitalized	—			(300		)	(700		)	(2,000		)	(2,300		)	(2,000		)
Preference dividends	—			(2,248		)	(3,981		)	(13,014		)	(22,353		)	(17,468		)
Add:
Fixed charges	—			26,508			48,441			131,614			128,613			99,388
Amortization of capitalized interest	—			20			103			270			539			804
Dividends from equity investees	—			—			—			94			94			225
(Losses) earnings as defined	$	(6,500	)	$	(16,731	)	$	129,792		$	199,299		$	206,558		$	309,405
Fixed charges:
Interest expense	$	—		$	21,500		$	39,900		$	110,200		$	97,200		$	72,800
Interest capitalized	—			300			700			2,000			2,300			2,000
Amortization of debt issuance costs and debt discount	—			1,300			2,300			3,800			3,800			3,800
Interest cost	—			23,100			42,900			116,000			103,300			78,600
Rents	—			5,800			7,800			13,000			14,800			16,600
Interest factor	—			20.0		%	20.0		%	20.0		%	20.0		%	20.0		%
Estimated interest component of rents	—			1,160			1,560			2,600			2,960			3,320
Preference dividends	—			2,248			3,879			13,014			14,364			11,744
Ratio of pre-tax (loss) income to (loss) income from continuing operations	—			1			102.6		%	1			155.6		%	148.7		%
Preferred dividend factor	—			2,248			3,981			13,014			22,353			17,468
Fixed charges as defined	$	—		$	26,508		$	48,441		$	131,614		$	128,613		$	99,388
Ratio of earnings to fixed charges (1)	—			—			2.68			1.51			1.61			3.11

(1) Earnings were insufficient to cover fixed charges and preference dividends by $43.2 million for the nine months ended December 31, 2005.

Talecris Biotherapeutics Holdings Corp.

Ratio of Earnings to Fixed Charges

(Dollars in thousands)

	Predecessor			Successor
	Three Months			Nine Months																					Pro forma
	Ended			Ended															Three Months Ended						Year Ended		Three Months Ended
	March 31,			December 31,			Years Ended December 31,												March 31,						December 31,		March 31,
	2005			2005			2006			2007			2008			2009			2009			2010			2009		2009
(Losses) earnings:
(Loss) income from continuing operations before income taxes	$	(6,500	)	$	(40,514	)	$	86,613		$	82,771		$	102,391		$	228,897		33,435			45,339
Deduct:
Earnings of equity investees	—			(197		)	(684		)	(436		)	(426		)	(441		)	(89		)	(147		)
Interest capitalized	—			(300		)	(700		)	(2,000		)	(2,300		)	(2,000		)	(300		)	(1,300		)
Preference dividends	—			(2,248		)	(3,981		)	(13,014		)	(22,353		)	(17,468		)	—			—
Add:
Fixed charges	—			26,508			48,441			131,614			128,613			99,388			26,548			15,420
Amortization of capitalized interest	—			20			103			270			539			804			180			202
Dividends from equity investees	—			—			—			94			94			225			—			—
(Losses) earnings as defined	$	(6,500	)	$	(16,731	)	$	129,792		$	199,299		$	206,558		$	309,405		$	59,774		$	59,514		$	309,405	$	59,774	historical
Fixed charges:
Interest expense	$	—		$	21,500		$	39,900		$	110,200		$	97,200		$	72,800		$	20,700		$	12,100
Interest capitalized	—			300			700			2,000			2,300			2,000			300			1,300
Amortization of debt issuance costs and debt discount	—			1,300			2,300			3,800			3,800			3,800			900			1,100
Interest cost	—			23,100			42,900			116,000			103,300			78,600			21,900			14,500
Rents	—			5,800			7,800			13,000			14,800			16,600			4,150			4,600
Interest factor	—			20.0		%	20.0		%	20.0		%	20.0		%	20.0		%	20.0		%	20.0		%
Estimated interest component of rents	—			1,160			1,560			2,600			2,960			3,320			830			920
Preference dividends	—			2,248			3,879			13,014			14,364			11,744			3,818			—
Ratio of pre-tax (loss) income to (loss) income from continuing operations	—			1			102.6		%	1			155.6		%	148.7		%	1			—
Preferred dividend factor	—			2,248			3,981			13,014			22,353			17,468			3,818			—
Fixed charges as defined	$	—		$	26,508		$	48,441		$	131,614		$	128,613		$	99,388		$	26,548		$	15,420		$	99,388	$	26,548	historical
																									35,914		$	2,805	adjustment
																									$	135,302	$	29,353
Ratio of earnings to fixed charges (1)	—			—			2.68			1.51			1.61			3.11			2.25			3.86			2.29		2.04

(1) Earnings were insufficient to cover fixed charges and preference dividends by $43.2 million for the nine months ended December 31, 2005.

Debt refinancted	$	550,000		$	550,000
7.75% Notes rate	7.75		%	7.75		%
Interest expense and bond rate	$	42,625		$	10,656
Weighted average historical rate	3.36		%	5.71		%
Interest expense and historical rate	18,480			7,851
Additional interest charge	$	24,145		$	2,805
Gross-up of interest charge	35,914			$	2,805