Income Taxes - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Reconciliation Of Income Taxes [Line Items]
Federal statutory income tax rate	21.00%	21.00%	21.00%
Increase in valuation allowance	$ 127,500,000	$ 62,400,000	$ 119,300,000
Valuation allowance changes, description	The Company does not expect any significant changes in its valuation allowance positions within the next 12 months.
Federal net operating loss carryforwards	$ 861,400,000	960,700,000
State net operating loss carryforward	741,000,000	677,000,000
International net operating loss carryforwards	8,600,000	8,500,000
Research and development tax credits, net of UTP	$ 125,424,000	$ 78,049,000
Minimum percentage chances of tax benefit to be realized on examination	50.00%
Unrecognized tax benefits affect the Company's effective tax rate	$ 0
Interest or penalties recorded	$ 0
Expected significant change in unrecognized tax benefits, description	The Company does not expect any significant change in its unrecognized tax benefits within the next 12 months.
Federal [Member]
Reconciliation Of Income Taxes [Line Items]
Research and development tax credits, net of UTP	$ 89,200,000
Research and development tax credit carryforwards, begin to expiration year	2030
State [Member]
Reconciliation Of Income Taxes [Line Items]
Net operating loss carryforwards, begin to expiration year	2025
Research and development tax credits, net of UTP	$ 34,100,000
Research and development tax credit carryforwards, begin to expiration year	2026