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Net loss per common stock - Additional Information (Detail) - shares
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Earnings Per Share [Abstract]      
Antidilutive securities excluded from the computation of basic and diluted net loss per share - outstanding stock options 2,897,294 2,069,167 1,378,352