License and Patent Agreements - Additional Information (Detail) CAD in Thousands	1 Months Ended			12 Months Ended
	Nov. 30, 2016 CAD	Jun. 30, 2014 shares	Aug. 31, 2009 CAD	Dec. 31, 2016 USD ($)	Dec. 31, 2016 CAD	Dec. 31, 2015 CAD	Dec. 31, 2014 CAD
Biolipox AB [Member]
Patent Licenses [Line Items]
License fee			CAD 50
Value of common stock shares issued for license fee			250
Payment of milestone	CAD 3,000
Amount of development milestones payment			3,000
Additional milestone payment payable			CAD 1,500
Royalty payments | $				$ 0
Biolipox AB [Member] | Goods and Services Exchanged for Equity Instrument [Member]
Patent Licenses [Line Items]
Number of common stock issued for payment for achievement of milestone | shares		19,762
SHIP1 Product Candidates [Member]
Patent Licenses [Line Items]
License agreement, maintenance fees					CAD 1	CAD 1
SHIP1 Product Candidates [Member] | First Drug Product [Member]
Patent Licenses [Line Items]
Amount of development milestones payment					2,200
SHIP1 Product Candidates [Member] | Subsequent Drug Product [Member]
Patent Licenses [Line Items]
Amount of development milestones payment					1,500
SHIP1 Enzyme and Screening of Product Candidates [Member]
Patent Licenses [Line Items]
License agreement, maintenance fees					CAD 5	CAD 5	CAD 5
License agreement expiration period				20 years	20 years