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Stockholders' equity - Additional Information (Detail) (USD $)
In Thousands, except Share data, unless otherwise specified
3 Months Ended 0 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Jan. 27, 2014
Dec. 31, 2014
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Total number of shares authorized 55,000,000aqxp_StockSharesAuthorizedNet      
Common stock, shares authorized 50,000,000us-gaap_CommonStockSharesAuthorized     50,000,000us-gaap_CommonStockSharesAuthorized
Common stock, par value $ 0.000001us-gaap_CommonStockParOrStatedValuePerShare     $ 0.000001us-gaap_CommonStockParOrStatedValuePerShare
Preferred stock, shares authorized 5,000,000us-gaap_PreferredStockSharesAuthorized      
Preferred stock, par value $ 0.000001us-gaap_PreferredStockParOrStatedValuePerShare      
Common stock, shares issued 10,723,128us-gaap_CommonStockSharesIssued     10,695,108us-gaap_CommonStockSharesIssued
Common stock, shares outstanding 10,723,128us-gaap_CommonStockSharesOutstanding     10,695,108us-gaap_CommonStockSharesOutstanding
Preferred stock, shares issued 0us-gaap_PreferredStockSharesIssued     0us-gaap_PreferredStockSharesIssued
Preferred stock, shares outstanding 0us-gaap_PreferredStockSharesOutstanding 0us-gaap_PreferredStockSharesOutstanding   0us-gaap_PreferredStockSharesOutstanding
Shares of common stock reserved for issuance description Additionally, the number of shares of common stock reserved for issuance under the 2014 Plan will automatically increase on January 1 of each year for a period of up to 10 years, beginning on January 1, 2015 and ending on and including January 1, 2024, by 4% of the total number of shares of capital outstanding on December 31 of the preceding calendar year, or a lesser number of shares determined by the board of directors.      
Shares of common stock reserved for issuance percentage 4.00%aqxp_StockBasedCompensationIncreaseInCommonStockIssuancePercentage      
Years of increase in shares of common stock reserved for issuance 10 years      
Stock options granted 271,750us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod      
Stock options granted, exercise price per share $ 11.70us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice      
Stock options, vesting period 5 years 10 months 17 days      
Common stock issued upon exercise of options 28,020us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised      
Stock-based compensation expense $ 266us-gaap_AllocatedShareBasedCompensationExpense $ 138us-gaap_AllocatedShareBasedCompensationExpense    
Unrecognized stock-based compensation cost $ 4,504us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized $ 1,486us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized    
Unrecognized stock-based compensation cost, weighted-average period recognized 3 years 1 month 2 days 1 year 5 months 19 days    
Employees [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted 241,750us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod
/ us-gaap_TitleOfIndividualAxis
= aqxp_EmployeesMember
     
Employees [Member] | Vesting of stock options granted to employees [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options, vesting percentage 25.00%us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage
/ us-gaap_TitleOfIndividualAxis
= aqxp_EmployeesMember
/ us-gaap_VestingAxis
= us-gaap_ShareBasedCompensationAwardTrancheOneMember
     
Employees [Member] | Minimum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted, exercise price per share $ 9.51us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
/ us-gaap_TitleOfIndividualAxis
= aqxp_EmployeesMember
     
Employees [Member] | Maximum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted, exercise price per share $ 12.03us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
/ us-gaap_TitleOfIndividualAxis
= aqxp_EmployeesMember
     
Director [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted 30,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod
/ us-gaap_TitleOfIndividualAxis
= us-gaap_DirectorMember
     
Non-employee Directors [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted, exercise price per share $ 12.03us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
/ us-gaap_TitleOfIndividualAxis
= aqxp_NonEmployeeDirectorsMember
     
Non-employee Directors [Member] | Condition (i) [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options, vesting period 1 year      
Non-employee Directors [Member] | Condition (ii) [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options, vesting period 3 years      
Equity Incentive Plan 2006 [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted     0us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
/ us-gaap_PlanNameAxis
= aqxp_EquityIncentivePlanTwoThousandSixMember
 
Equity Incentive Plan 2014 [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Maximum number of shares of common stock that may be issued 1,851,220us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= aqxp_StockIncentivePlanTwoThousandFourteenMember
     
Stock options, expiration period 10 years