Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Operating activities
Net loss	$ (34,506)	$ (22,811)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization		5
Amortization of operating lease asset	195	178
Warrant inducement expense		4,829
Stock-based compensation	7,904	3,171
Deferred income taxes	(2,354)	(404)
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(2,095)	39
Accounts payable and accrued expenses	2,143	(39)
Operating lease liability	(200)	(180)
Net cash used in operating activities	(28,913)	(15,212)
Investing activities
Cash and cash equivalents received from acquisition		11,035
Net cash provided by investing activities		11,035
Financing activities
Proceeds from issuance of common stock, net		9,000
Proceeds from issuance of non-voting preferred stock in connection with PIPE transaction, net		95,226
Proceeds from exercise of warrants, net		5,380
Proceeds from exercise of stock options	1
Payment of offering costs in connection with PIPE transaction	(450)
Cash paid for cancellation of common stock in connection with reverse split		(25)
Net cash (used in) provided by financing activities	(449)	109,581
Net change in cash and cash equivalents	(29,362)	105,404
Cash and cash equivalents at beginning of year	114,195	8,791
Cash and cash equivalents at end of year	84,833	114,195
Supplemental disclosure of non-cash investing and financing activities
Increase in operating lease asset and liability due to new and modified operating leases	825
Common stock exchange for warrants	$ 1
Conversion of Series X1 non-voting convertible preferred stock into common stock		13
Issuance of common stock in acquisition		1,194
Issuance of Series X non-voting convertible preferred stock in acquisition		69,723
Fair value of options assumed in acquisition		2,950
Fair value of warrants assumed in acquisition		12,944
Accrued offering costs		$ 450