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Statements of Stockholders' Equity - USD ($)
Total
Common Stock [Member]
Additional Paid-In Capital [Member]
Accumulated Deficit [Member]
Beginning Balance at Dec. 31, 2014 $ 9,188,664 $ 611 $ 45,127,202 $ (35,939,149)
Beginning Balance, Shares at Dec. 31, 2014   6,112,091    
Stock-based compensation expense 1,504,356   1,504,356  
Issuance of common stock from At-The-Market offering, net 4,723,572 $ 105 4,723,467  
Issuance of common stock from At-The-Market offering, shares net   1,048,507    
Issuance of common stock from employee stock purchase plan $ 169,800 $ 4 169,796  
Issuance of common stock from employee stock purchase plan, Shares 41,176 41,176    
Net loss $ (12,121,463)     (12,121,463)
Ending Balance at Dec. 31, 2015 $ 3,464,929 $ 720 51,524,821 (48,060,612)
Ending Balance, Shares at Dec. 31, 2015 7,201,774 7,201,774    
Stock-based compensation expense $ 1,706,524   1,706,524  
Issuance of common stock from At-The-Market offering, net 256,113 $ 6 256,107  
Issuance of common stock from At-The-Market offering, shares net   56,000    
Issuance of common stock from employee stock purchase plan $ 98,742 $ 3 98,739  
Issuance of common stock from employee stock purchase plan, Shares 34,067 34,067    
Issuance of common stock from warrant exercise   $ 1 (1)  
Issuance of common stock from warrant exercise, Shares   9,887    
Issuance of common stock and warrants, net $ 8,803,036 $ 505 8,802,531  
Issuance of common stock and warrants, shares net   5,048,632    
Reclassification of warrant liability due to warrant amendment 206,825   206,825  
Net loss (10,748,531)     (10,748,531)
Ending Balance at Dec. 31, 2016 $ 3,787,638 $ 1,235 $ 62,595,546 $ (58,809,143)
Ending Balance, Shares at Dec. 31, 2016 12,350,360 12,350,360