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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Cash flows from operating activities:    
Net loss $ (6,339) $ (13,542)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 906 741
Noncash rent expense 10 124
Depreciation and amortization 66 61
Amortization of debt discount and deferred financing costs 610 127
Loss on disposal of property and equipment   4
Impairment of property and equipment 102  
Deferred revenue (625)  
Gain on asset sale (1,500)  
Changes in operating assets and liabilities:    
Accounts receivable (316) (18)
Prepaid expenses and other current assets (1,039) (174)
Accounts payable (802) 141
Accrued expenses (1,073) (724)
Net cash used in operating activities (10,000) (13,260)
Cash flows from investing activities:    
Purchases of property and equipment   (359)
Decrease in restricted cash   117
Proceeds from the sale of assets 1,500  
Net cash provided by (used in) investing activities 1,500 (242)
Cash flows from financing activities:    
Proceeds from sale of common stock 62 41
Payments on loan payable (13,077) (1,932)
Payment of end of term charge on loan payable (1,407)  
Net cash used in financing activities (14,422) (1,891)
Net decrease increase in cash and cash equivalents (22,922) (15,393)
Cash and cash equivalents - Beginning of period 34,950 75,908
Cash and cash equivalents - End of period 12,028 60,515
Supplemental cash flow information - Interest paid $ 269 $ 372