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Components of Prepaid Expenses and Other (Detail) - USD ($)
$ in Thousands
Dec. 31, 2019
Dec. 31, 2018
Prepaid Expenses [Line Items]    
Prepaid expenses and other, current $ 13,259 $ 12,397
Prepaid expenses and other, long-term 1,999 3,429
Totals 15,258 15,826
CRO services    
Prepaid Expenses [Line Items]    
Prepaid expenses and other, current 4,810 5,824
Prepaid expenses and other, long-term 400 1,073
Other clinical development    
Prepaid Expenses [Line Items]    
Prepaid expenses and other, current 2,043 888
Prepaid expenses and other, long-term 468 650
Insurance    
Prepaid Expenses [Line Items]    
Prepaid expenses and other, current 3,452 2,446
Professional fees    
Prepaid Expenses [Line Items]    
Prepaid expenses and other, current 544 272
Other    
Prepaid Expenses [Line Items]    
Prepaid expenses and other, current 2,410 2,967
Prepaid expenses and other, long-term $ 1,131 $ 1,706