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Components of Net Deferred Tax Assets (Detail) - USD ($)
$ in Thousands
Dec. 31, 2015
Dec. 31, 2014
Deferred tax assets    
Net operating loss carry forwards $ 146,733 $ 83,808
Business credit carryforwards 17,901 9,928
Organization costs 195 217
Compensation 44,683 14,268
Depreciation 210 128
Other 62 84
Deferred Tax Assets, Gross, Total 209,784 108,433
Total deferred tax assets 209,784 108,433
Valuation allowance (209,784) (108,433)
Net deferred tax assets 0 0
Federal    
Deferred tax assets    
Net operating loss carry forwards 125,244 71,535
Business credit carryforwards 11,528 6,499
Organization costs 166 185
Compensation 38,138 12,178
Depreciation 180 109
Other 53 72
Deferred Tax Assets, Gross, Total 175,309 90,578
Total deferred tax assets 175,309 90,578
Valuation allowance (175,309) (90,578)
Net deferred tax assets 0 0
State    
Deferred tax assets    
Net operating loss carry forwards 21,489 12,273
Business credit carryforwards 6,373 3,429
Organization costs 29 32
Compensation 6,545 2,090
Depreciation 30 19
Other 9 12
Deferred Tax Assets, Gross, Total 34,475 17,855
Total deferred tax assets 34,475 17,855
Valuation allowance (34,475) (17,855)
Net deferred tax assets $ 0 $ 0