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                             September 8, 2022

       Raymond Silcock
       Chief Financial Officer
       Neptune Wellness Solutions Inc.
       545 Promenade du Centropolis, Suite 100
       Laval, Quebec
       Canada H7T 0A3

                                                        Re: Neptune Wellness
Solutions Inc.
                                                            Registration
Statement on Form S-3
                                                            Filed August 25,
2022
                                                            File No. 333-267070

       Dear Mr. Silcock:

              We have limited our review of your registration statement to
those issues we have
       addressed in our comment. In our comment, we may ask you to provide us
with information so
       we may better understand your disclosure.

              Please respond to this letter by amending your registration
statement and providing the
       requested information. If you do not believe our comment applies to your
facts and
       circumstances or do not believe an amendment is appropriate, please tell
us why in your
       response.

              After reviewing any amendment to your registration statement and
the information you
       provide in response to this comment, we may have additional comments.

       Registration Statement on Form S-3 filed August 25, 2022

       General

   1.                                                   We note that you are
incorporated in Canada with your principal executive offices located
                                                        in Quebec. We also note
that you are no longer considered a foreign private issuer and
                                                        have recently commenced
filing reports required for a domestic registrant. In this regard,
                                                        General Instruction
I.A.5 of Form S-3 states that foreign issuers which file the same
                                                        reports with the
Commission under Section 13(a) or 15(d) of the Exchange Act as those
                                                        required for a domestic
registrant may use Form S-3 even though it does not meet the
                                                        provisions of General
Instruction I.A.1. Please provide us with your analysis
                                                        explaining how you are
eligible to conduct this offering on Form S-3 at this time. If you
                                                        are not eligible to use
Form S-3 for this offering, please withdraw this registration
 Raymond Silcock
Neptune Wellness Solutions Inc.
September 8, 2022
Page 2
      statement and refile on an appropriate form.
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.

       Refer to Rules 460 and 461 regarding requests for acceleration. Please
allow adequate
time for us to review any amendment prior to the requested effective date of
the registration
statement.

       Please contact Tyler Howes at 202-551-3370 or Dorrie Yale at
202-551-8776 with any
questions.



                                                           Sincerely,
FirstName LastNameRaymond Silcock
                                                           Division of
Corporation Finance
Comapany NameNeptune Wellness Solutions Inc.
                                                           Office of Life
Sciences
September 8, 2022 Page 2
cc:       Thomas Rose, Esq.
FirstName LastName