0000950123-22-009421.txt : 20220815 0000950123-22-009421.hdr.sgml : 20220815 20220815160235 ACCESSION NUMBER: 0000950123-22-009421 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220630 FILED AS OF DATE: 20220815 DATE AS OF CHANGE: 20220815 EFFECTIVENESS DATE: 20220815 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Flagship Pioneering Inc. CENTRAL INDEX KEY: 0001400240 IRS NUMBER: 752992246 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-17559 FILM NUMBER: 221165590 BUSINESS ADDRESS: STREET 1: 55 CAMBRIDGE PARKWAY, SUITE 800E CITY: CAMBRIDGE STATE: MA ZIP: 02142 BUSINESS PHONE: 617 868-1888 MAIL ADDRESS: STREET 1: 55 CAMBRIDGE PARKWAY, SUITE 800E CITY: CAMBRIDGE STATE: MA ZIP: 02142 FORMER COMPANY: FORMER CONFORMED NAME: Flagship Ventures Management, Inc. DATE OF NAME CHANGE: 20070522 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001400240 XXXXXXXX 06-30-2022 06-30-2022 false Flagship Pioneering Inc.

55 Cambridge Parkway, Suite 800E Cambridge MA 02142

13F HOLDINGS REPORT 028-17559 N Noubar B. Afeyan, Ph.D. 617-868-1888 /s/ Noubar B. Afeyan Cambridge MA 08-15-2022 7 33 2654624 false 1 028-18466 Flagship Ventures Fund V General Partner LLC 2 028-17238 Flagship Ventures Fund IV General Partner LLC 3 028-19988 Noubar Afeyan 4 028-20999 Flagship Opportunities Fund I General Partner LLC 5 028-20997 Flagship Pioneering Special Opportunities Fund II General Partner LLC 6 028-21001 Nutritional Health Fund LTP General Partner LLC 7 028-20998 Flagship Pioneering Fund VI General Partner LLC INFORMATION TABLE 2 16086.xml INFORMATION TABLE FOR FORM 13F Axcella Health Inc COM 05454B105 25661 12640890 SH DFND 2,3 0 12640890 0 Axcella Health Inc COM 05454B105 9066 4465866 SH DFND 3,4 0 4465866 0 Axcella Health Inc COM 05454B105 3575 1761029 SH DFND 3 0 1761029 0 Codiak Biosciences Inc COM 192010106 6110 2121354 SH DFND 1,3 0 2121354 0 Codiak Biosciences Inc COM 192010106 1400 485949 SH DFND 3 0 485949 0 Denali Therapeutics Inc COM 24823R105 77106 2619968 SH DFND 1,3 0 2619968 0 Evelo Biosciences Inc COM 299734103 21443 10205282 SH DFND 1,3 0 10205282 0 Evelo Biosciences Inc COM 299734103 21533 10162664 SH DFND 2,3 0 10162664 0 Evelo Biosciences Inc COM 299734103 11595 5495324 SH DFND 3,4 0 5495324 0 Evelo Biosciences Inc COM 299734103 17344 8219791 SH DFND 3,6 0 8219791 0 Evelo Biosciences Inc COM 299734103 34486 16344267 SH DFND 3 0 16344267 0 Foghorn Therapeutics Inc COM 344174107 126900 9330878 SH DFND 1,3 0 9330878 0 Foghorn Therapeutics Inc COM 344174107 20284 1491441 SH DFND 3,4 0 1491441 0 Foghorn Therapeutics Inc COM 344174107 25184 1851801 SH DFND 3,5 0 1851801 0 Moderna Inc COM 60770K107 1840311 12882819 SH DFND 2,3 0 12882819 0 Moderna Inc COM 60770K107 561 3924 SH DFND 3 0 3924 0 Omega Therapeutics Inc COM 68217N105 26542 6984856 SH DFND 1,3 0 6984856 0 Omega Therapeutics Inc COM 68217N105 20956 5514707 SH DFND 3,5 0 5514707 0 Omega Therapeutics Inc COM 68217N105 3688 970588 SH DFND 3,6 0 970588 0 Omega Therapeutics Inc COM 68217N105 32746 8617413 SH DFND 3,7 0 8617413 0 Omega Therapeutics Inc COM 68217N105 14496 3814705 SH DFND 3 0 3814705 0 Rubius Therapeutics Inc COM 78116T103 9902 11648828 SH DFND 1,3 0 11648828 0 Rubius Therapeutics Inc COM 78116T103 20590 24223995 SH DFND 2,3 0 24223995 0 Rubius Therapeutics Inc COM 78116T103 2239 2633703 SH DFND 3,4 0 2633703 0 Sana Biotechnology Inc COM 799566104 84057 13072570 SH DFND 1,3 0 13072570 0 Sana Biotechnology Inc COM 799566104 62533 9725122 SH DFND 3,7 0 9725122 0 Sana Biotechnology Inc COM 799566104 73568 11441326 SH DFND 3 0 11441326 0 Seres Therapeutics Inc COM 81750R102 28993 8452876 SH DFND 2,3 0 8452876 0 Seres Therapeutics Inc COM 81750R102 10163 2962963 SH DFND 3,7 0 2962963 0 Seres Therapeutics Inc COM 81750R102 10163 2962963 SH DFND 3,6 0 2962963 0 Sigilon Therapeutics Inc COM 82657L107 7378 8888888 SH DFND 1,3 0 8888888 0 Sigilon Therapeutics Inc COM 82657L107 1230 1481481 SH DFND 3,5 0 1481481 0 Syros Pharmaceuticals Inc COM 87184Q107 2821 2938494 SH DFND 2,3 0 2938494 0