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Company Overview and Equity Transactions (Details)
12 Months Ended 25 Months Ended
Sep. 07, 2022
USD ($)
Jun. 06, 2022
USD ($)
shares
Mar. 26, 2021
USD ($)
Sep. 11, 2019
USD ($)
$ / shares
Dec. 31, 2022
USD ($)
licensedCommercializedProduct
$ / shares
shares
Dec. 31, 2021
USD ($)
$ / shares
shares
Dec. 31, 2022
USD ($)
licensedCommercializedProduct
$ / shares
shares
Apr. 12, 2022
USD ($)
Class of Stock [Line Items]                
Number of licensed commercialized products | licensedCommercializedProduct         5   5  
Common stock, par or stated value per share (in dollars per share) | $ / shares         $ 0.001 $ 0.001 $ 0.001  
Cost of common stock issued under equity offering         $ (289,000) $ (1,291,000)    
Ownership limitation, maximum percent of beneficial ownership               9.99%
Common stock, shares outstanding (in shares) | shares         54,827,734 41,228,736 54,827,734  
Common Stock                
Class of Stock [Line Items]                
Common stock issued under equity offering (in shares) | shares         2,860,538 6,550,486    
Equity Distribution Agreement                
Class of Stock [Line Items]                
Sale of stock, aggregate offering price       $ 25,000,000        
Common stock, par or stated value per share (in dollars per share) | $ / shares       $ 0.001        
Equity Distribution Agreement | Maximum                
Class of Stock [Line Items]                
Sale of stock, aggregate offering price $ 35,000              
At The Market Offering, Amendment One | Maximum                
Class of Stock [Line Items]                
Sale of stock, aggregate offering price     $ 50,000,000          
At The Market Offering                
Class of Stock [Line Items]                
Consideration received on sale of stock         $ 3,907,000 $ 29,778,000 $ 39,740,000  
Remaining amount available for offering         33,416,000      
Number of shares issued in transaction (in shares) | shares             10,341,957  
Lincoln Park Agreement                
Class of Stock [Line Items]                
Consideration received on sale of stock         $ 1,987,000      
Right to sell common stock, value               $ 40,000
Agreement term (in months)               36 months
Number of shares issued in transaction (in shares) | shares         1,600,000      
Commitment shares issued (in shares) | shares         236,491      
Securities Purchase Agreement                
Class of Stock [Line Items]                
Common stock, shares outstanding (in shares) | shares   4,850,000            
Common stock entitled to purchasers by pre-funded warrants (in shares) | shares   4,000,000            
Stock to be purchased by common stock warrants (in shares) | shares   8,850,000            
Net proceeds after placement agent fees, expenses, and offering expenses payable   $ 7,796,000