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Share-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2019
Share-Based Compensation [Abstract]  
Share-based Compensation Expense
The Company recognized share-based compensation in its Condensed Consolidated Statements of Operations and Comprehensive Loss during 2019 and 2018 as follows:

  
Three Months Ended
September 30,
  
Nine Months Ended
September 30,
 
Expense classification:
 
2019
  
2018
  
2019
  
2018
 
Manufacture and supply
 
$
60
  
$
32
  
$
176
  
$
377
 
Research and development
  
188
   
192
   
536
   
2,378
 
Selling, general and administrative
  
1,622
   
1,102
   
4,480
   
25,786
 
Total share-based compensation expenses
 
$
1,870
  
$
1,236
  
$
5,200
  
$
28,541
 
                 
Share-based compensation from:
                
Restricted stock units
 
$
473
  
$
610
  
$
1,403
  
$
610
 
Stock options
  
1,397
   
626
   
3,777
   
633
 
Non-voting common shares
  
--
   
   
--
   
27,298
 
Employee stock purchase plan
  
--
   
   
20
   
 
Total share-based compensation expenses
 
$
1,870
  
$
1,236
  
$
5,200
  
$
28,541
 
Restricted Stock Units Awards
The following tables provide information about the Company’s restricted stock and stock option unit activity during the nine months ended September 30, 2019:

Restricted stock units:
 
Number of
Units
  
Weighted Average
Grant Date Fair
Value
 
  
(in thousands)
    
Unvested at December 31, 2018
  
205
  
$
14.77
 
Granted
  
--
   
--
 
Vested
  
(95
)
  
14.91
 
Forfeited
  
(3
)
  
13.00
 
Unvested at September 30, 2019
  
107
  
$
14.70
 
Grant date fair value of shares vested during the period
 
$
1,421
     
Unrecognized compensation costs of RSU awards at September 30, 2019
 
$
1,409
     
Stock Option Activity
Stock options:
 
Number of
Options
  
Weighted Average
Exercise Price
 
  
(in thousands)
    
Outstanding at December 31, 2018
  
1,033
  
$
14.72
 
Granted
  
1,253
   
6.67
 
Forfeited
  
(30
)
  
7.73
 
Exercised, expired
  
--
   
--
 
Outstanding at September 30, 2019
  
2,256
  
$
10.34
 
Vested or expected to vest at September 30, 2019
  
2,113
  
$
10.28
 
Exercisable at September 30, 2019
  
345
  
$
14.79
 
Valuation Assumptions for Determination of Fair Value of Options
The fair values of stock options granted during 2019 were estimated using the Black-Scholes-Merton pricing model based on the following assumptions:

Expected dividend yield
 
0
%
Expected volatility
 
85 - 95
%
Expected term (years)
 
5.5 - 6.1
 
Risk-free interest rate
 
1.5 - 2.6
%