The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADICET BIO INC | COM | 007002108 | 18,911,542 | 2,115,385 | SH | DFND | 1 | 0 | 2,115,385 | 0 | ||
| AEGLEA BIOTHERAPEUTICS INC | COM | 00773J103 | 108,225 | 240,500 | SH | DFND | 1 | 0 | 240,500 | 0 | ||
| CYMABAY THERAPEUTICS INC | COM | 23257D103 | 821,596 | 131,036 | SH | DFND | 1 | 0 | 131,036 | 0 | ||
| EFFECTOR THERAPEUTICS INC | COM | 28202V108 | 2,063,865 | 4,822,114 | SH | DFND | 1 | 0 | 4,822,114 | 0 | ||
| EXICURE INC | COM NEW | 30205M200 | 323,881 | 281,636 | SH | DFND | 1 | 0 | 281,636 | 0 | ||
| HILLEVAX INC | COM | 43157M102 | 30,757,871 | 1,838,486 | SH | DFND | 1 | 0 | 1,838,486 | 0 | ||
| JASPER THERAPEUTICS INC | COM | 471871103 | 2,718,594 | 5,628,558 | SH | DFND | 1 | 0 | 5,628,558 | 0 | ||
| MOLECULAR TEMPLATES INC | COM | 608550109 | 66,000 | 200,000 | SH | DFND | 1 | 0 | 200,000 | 0 | ||
| NUCANA PLC | SPONSORED ADR | 67022C106 | 2,200,000 | 3,333,333 | SH | DFND | 1 | 0 | 3,333,333 | 0 | ||
| OBSEVA SA | COM | H5861P103 | 12,760 | 87,999 | SH | DFND | 1 | 0 | 87,999 | 0 | ||
| PARATEK PHARMACEUTICALS INC | COM | 699374302 | 1,946,915 | 1,041,131 | SH | DFND | 1 | 0 | 1,041,131 | 0 | ||
| PHATHOM PHARMACEUTICALS INC | COM | 71722W107 | 16,101,889 | 1,435,106 | SH | DFND | 1 | 0 | 1,435,106 | 0 | ||
| RENEO PHARMACEUTICALS INC | COM | 75974E103 | 4,832,320 | 2,073,957 | SH | DFND | 1 | 0 | 2,073,957 | 0 | ||
| SIENTRA INC | COM | 82621J105 | 3,397,386 | 1,673,589 | SH | DFND | 1 | 0 | 1,673,589 | 0 | ||
| SOLENO THERAPEUTICS INC | COM | 834203309 | 2,378,982 | 1,201,506 | SH | DFND | 1 | 0 | 1,201,506 | 0 | ||
| SPRUCE BIOSCIENCES INC | COM | 85209E109 | 1,966,392 | 1,792,518 | SH | DFND | 1 | 0 | 1,792,518 | 0 | ||
| VAXCYTE INC | COM | 92243G108 | 96,813,783 | 2,019,057 | SH | DFND | 1 | 0 | 2,019,057 | 0 | ||
| VERA THERAPEUTICS INC | CL A | 92337R101 | 57,280,470 | 2,960,231 | SH | DFND | 1 | 0 | 2,960,231 | 0 | ||
| VERONA PHARMA PLC | SPONSORED ADS | 925050106 | 64,214,475 | 2,457,500 | SH | DFND | 1 | 0 | 2,457,500 | 0 | ||