The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Aeglea Common 00773J103 1,893 240,500 SH   DFND   240,500 0 0
Cymabay Common 23257D103 752 131,036 SH   DFND   131,036 0 0
Exicure Common 30205M101 12,349 6,977,000 SH   DFND   6,977,000 0 0
Molecular Templates Common 608550109 1,884 200,000 SH   DFND   200,000 0 0
Nucana ADS 67022C106 14,967 3,333,333 SH   DFND   3,333,333 0 0
Obseva Common H5861P103 182 87,999 SH   DFND   87,999 0 0
Ocugen Common 43358V109 13 7,111 SH   DFND   7,111 0 0
Paratek Common 699374302 6,517 1,041,131 SH   DFND   1,041,131 0 0
Phathom Common 71722W107 39,956 1,203,135 SH   DFND   1,203,135 0 0
Sientra Common 82621J105 9,300 2,390,843 SH   DFND   2,390,843 0 0
Sierra Oncology Common 82640U107 13,903 871,125 SH   DFND   871,125 0 0
Soleno Common 834203200 19,884 10,302,602 SH   DFND   10,302,602 0 0
Spruce Bio Common E5209E109 43,074 1,792,518 SH   DFND   1,792,518 0 0
Vaxcyte Common 92243G108 110,721 4,168,718 SH   DFND   4,168,718 0 0
Verona SPONDS ADR 925050106 16,932 2,457,499 SH   DFND   2,457,499 0 0