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STOCK PLANS (Tables)
3 Months Ended
Mar. 31, 2020
Stockholders' Equity Note [Abstract]  
Schedule of recognized stock-based compensation in consolidated statements of operations
The Company recognized stock-based compensation expense in the periods presented as follows (in thousands):

Three Months Ended
March 31,
20202019
Cost of goods sold$1,219  $1,091  
Research and development1,186  1,218  
Selling, general and administrative6,442  5,125  
        Total$8,847  $7,434  
Stock-based compensation from:
    Stock options$6,225  $5,121  
    Restricted stock units2,402  2,107  
    Employee stock purchase plan220  206  
        Total$8,847  $7,434  
Schedule of the Company's stock option activity and related information
The following tables contain information about the Company’s stock option and restricted stock unit, or RSU, activity for the three months ended March 31, 2020:
Stock Options Number of Options Weighted Average Exercise Price (Per Share)
 Outstanding at December 31, 20196,706,378  $42.80  
     Granted188,450  43.53  
     Exercised(207,548) 16.64  
     Forfeited(91,069) 41.66  
     Expired(14,057) 63.34  
 Outstanding at March 31, 20206,582,154  43.62  

Restricted Stock Units Number of Units Weighted Average Grant Date Fair Value (Per Share)
Unvested at December 31, 2019631,141  $41.87  
     Granted350  43.27  
     Vested(849) 48.16  
     Forfeited(15,567) 41.89  
Unvested at March 31, 2020615,075  41.86