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FIXED ASSETS (Tables)
3 Months Ended
Mar. 31, 2019
Property, Plant and Equipment [Abstract]  
Schedule of fixed assets summarized by major category Fixed assets, net, summarized by major category, consist of the following (in thousands):
 
March 31,
 
December 31,
 
2019
 
2018
Machinery and laboratory equipment
$
67,913

 
$
67,431

Leasehold improvements
59,886

 
57,955

Computer equipment and software
8,188

 
8,131

Office furniture and equipment
1,576

 
1,548

Construction in progress
34,646

 
35,163

        Total
172,209

 
170,228

Less: accumulated depreciation
(65,158
)
 
(61,558
)
        Fixed assets, net
$
107,051

 
$
108,670