Consolidated Balance Sheets (USD $) In Thousands, unless otherwise specified	Dec. 31, 2011	Dec. 31, 2010
Current assets:
Cash and cash equivalents	$ 46,168	$ 26,133
Restricted cash	1,299	1,314
Short-term investments	29,985
Trade accounts receivable	2,113	1,191
Inventories	1,245	1,605
Prepaid expenses and other current assets	1,839	812
Total current assets	82,649	31,055
Fixed assets, net	25,103	23,950
Intangibles, net	5,259	8,912
Other assets	479	2,645
Total assets	113,490	66,562
Current liabilities:
Accounts payable	3,440	4,315
Accrued expenses	7,159	4,983
Current portion of royalty interest obligation	1,219	1,575
Current portion of deferred revenue	13,054	2,267
Current portion of long-term debt	7,039	3,182
Total current liabilities	31,911	16,322
Related party debt, including accrued interest		49,795
Long-term debt	18,537	21,869
Royalty interest obligation	1,537	2,996
Deferred revenue	8,416	18,138
Contingent purchase liability	2,042	2,042
Other liabilities	2,778	3,783
Total liabilities	65,221	114,945
Commitments and contingencies
Stockholders' equity (deficit):
Preferred stock, par value $0.001; 5,000,000 shares authorized, none issued and outstanding at December 31, 2011; 88,000,000 shares authorized, 6,322,640 shares issued and outstanding at December 31, 2010		6
Common stock, par value $0.001; 250,000,000 shares authorized, 25,340,103 shares issued and 25,339,038 shares outstanding at December 31, 2011; 120,000,000 authorized, 575,095 shares issued and 574,030 shares outstanding at December 31, 2010	25	1
Additional paid-in capital	228,470	88,523
Accumulated deficit	(180,239)	(136,911)
Accumulated other comprehensive income	15
Treasury stock at cost, 1,065 shares	(2)	(2)
Total stockholders' equity (deficit)	48,269	(48,383)
Total liabilities and stockholders' equity (deficit)	$ 113,490	$ 66,562