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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (52,735) $ (42,047)
Adjustments to reconcile net loss to net cash from operating activities:    
Depreciation 68 (580)
Amortization and accretion of investments (195)  
Non-cash operating lease expense 321 226
Non-cash interest expense 276  
Stock-based compensation 7,022 4,480
Other 2 2
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (5,789) (62)
Accounts payable (2,342) 5,193
Deferred revenue (1,138) (1,138)
Accrued expenses and other liabilities (1,119) (3,959)
Net cash used in operating activities (55,629) (37,885)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of short-term investments (150,350) (68,892)
Proceeds from sales and maturities of short-term investments 71,960 75,077
Net cash (used in)/provided by investing activities (78,390) 6,185
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from debt agreement, net 19,730  
Proceeds from Employee Stock Purchase Plan 242 125
Proceeds from stock option exercises 3,060 178
Net cash provided by financing activities 165,766 28,512
NET INCREASE (DECREASE) IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH 31,747 (3,188)
CASH, CASH EQUIVALENTS AND RESTRICTED CASH—beginning of period 24,724 33,985
CASH, CASH EQUIVALENTS AND RESTRICTED CASH —end of period 56,471 30,797
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:    
Cash paid for interest 1,133  
SUPPLEMENTAL DISCLOSURES OF NONCASH INVESTING AND FINANCING ACTIVITIES:    
Issuance costs in accounts payable and accrued expenses   126
At-the-Market Offering [Member]    
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of common stock, net   830
Private Placement [Member]    
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of common stock, net $ 142,734 $ 27,379