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Summary of Significant Accounting Policies - Additional Information (Detail)
12 Months Ended
Dec. 31, 2016
USD ($)
Claim
Segment
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Sep. 30, 2014
USD ($)
Summary Of Significant Accounting Policies [Line Items]        
Number of operating segments | Segment 1      
Capitalized deferred issuance costs       $ 4,300,000
Series A [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Preferred stock, liquidation preference   $ 0    
Guarantees and Indemnifications [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Indemnification obligations, claims outstanding | Claim 0      
Indemnification obligations claims, reserves established $ 0      
Cost-Sharing Collaborations [Member]        
Summary Of Significant Accounting Policies [Line Items]        
External costs related to cost-sharing collaborations 500,000 0 $ 0  
Cost-sharing collaborations recorded as a reduction to research and development expense $ (300,000)      
Minimum [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Estimated useful lives P3Y      
Percentage of income tax contingency realized 50.00%      
Maximum [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Estimated useful lives P5Y      
Initial Public Offering [Member]        
Summary Of Significant Accounting Policies [Line Items]        
Capitalized deferred issuance costs $ 0 $ 1,600,000