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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (224,589) $ (136,887)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 8 9
Accretion of investments (10,528) (11,344)
Non-cash operating lease expense 781 496
Stock-based compensation 30,729 22,624
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (11,567) (3,281)
Collaboration (payable) receivable, net (1,726) 68
Other receivable (3,507) 0
Other assets 463 0
Accounts payable (5,063) 1,699
Accrued expenses and other liabilities 7,484 7,364
Net cash used in operating activities (217,515) (119,252)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of short and long-term investments (180,738) (225,316)
Proceeds from sales and maturities of short-term investments 229,936 359,215
Net cash provided by investing activities 49,198 133,899
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from Employee Stock Purchase Plan 1,081 633
Proceeds from stock option exercises 4,861 5,016
Net cash provided by financing activities 5,942 5,649
NET (DECREASE) INCREASE CASH, CASH EQUIVALENTS AND RESTRICTED CASH (162,375) 20,296
CASH, CASH EQUIVALENTS AND RESTRICTED CASH—beginning of period 295,611 74,471
CASH, CASH EQUIVALENTS AND RESTRICTED CASH —end of period $ 133,236 $ 94,767