Commitments and Contingencies - Additional Information (Detail) - USD ($)	1 Months Ended
	Dec. 31, 2021	Sep. 30, 2021	Dec. 31, 2023	Dec. 31, 2022	Apr. 30, 2013
Commitment And Contingencies [Line Items]
Contingent liabilities			$ 0	$ 0
Eddingpharm Purchase Agreement [Member]
Commitment And Contingencies [Line Items]
Purchase agreement obligation					$ 5,000,000
Incyte Agreement [Member] | Global and U.S. [Member]
Commitment And Contingencies [Line Items]
Development costs associated with clinical trials		45.00%
Incyte Agreement [Member] | Non-Refundable Cash Payments [Member]
Commitment And Contingencies [Line Items]
Upfront milestone payable	$ 117,000,000	$ 117,000,000
Incyte Agreement [Member] | Equity Investment [Member]
Commitment And Contingencies [Line Items]
Upfront milestone payable		$ 35,000,000