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Stock-Based Awards - Inducement Stock Option Awards (Detail) - $ / shares
12 Months Ended
Feb. 01, 2021
Dec. 10, 2020
Jul. 09, 2019
Jun. 20, 2017
Dec. 31, 2021
Stock-Based Awards          
Shares Issuable Under Options, Granted         3,339,974
Exercise price (in dollars per share)         $ 17.22
Non-statutory Stock Option | Management          
Stock-Based Awards          
Shares Issuable Under Options, Granted     60,000 590,000  
Exercise price (in dollars per share)     $ 5.13 $ 10.94  
Vesting period     4 years 4 years  
Percentage of shares underlying the option award vesting on first anniversary     25.00% 25.00%  
Percentage of shares underlying the option award vesting monthly after the first anniversary     75.00% 75.00%  
2019 Inducement Plan          
Stock-Based Awards          
Number of shares of common stock authorized for issuance   1,054,000      
Number of shares of common stock available for issuance         510,252
Additional number of shares authorized for issuance   554,000      
2019 Inducement Plan | Non-Statutory Stock Option Vesting Based on Time | Senior Vice President, Clinical Development          
Stock-Based Awards          
Shares Issuable Under Options, Granted 100,000        
Exercise price (in dollars per share) $ 18.70        
Vesting period 4 years        
Percentage of shares underlying the option award vesting on first anniversary 25.00%        
2019 Inducement Plan | Non-Statutory Stock Option Vesting Based on Performance | Senior Vice President, Clinical Development          
Stock-Based Awards          
Shares Issuable Under Options, Granted 5,000,000        
Exercise price (in dollars per share) $ 18.70        
Percentage of shares underlying the option award vesting monthly after the first anniversary 75.00%