Stock-Based Awards (Tables)

12 Months Ended

Dec. 31, 2021

Stock-Based Awards

Schedule of Assumptions Used to Determine Fair Value of Stock Options Granted to Employees and Directors Presented on Weighted Average Basis

	Year Ended
	December 31,
	2021		2020		2019
Risk-free interest rate	0.80	%	1.12	%	2.25	%
Expected term (in years)	6		6		6
Expected volatility	87.65	%	86.00	%	87	%
Expected dividend yield	—	%	—	%	—	%

Schedule of Stock Option Activity

				Weighted
		Weighted		Average
		Average		Remaining	Aggregate
	Shares Issuable	Exercise		Contractual	Intrinsic
	Under Options	Price		Term	Value
				(In years)
Outstanding as of December 31, 2020	9,114,735	$	6.66	7.4	$	16,075
Granted	3,339,974		17.22
Exercised	(598,924)		4.32
Forfeited	(920,957)		11.48
Outstanding as of December 31, 2021	10,934,828	$	9.60	7.1		13,283
Options vested and expected to vest as of December 31, 2021	9,504,572	$	8.93	6.8		12,381
Options exercisable as of December 31, 2021	6,570,556	$	8.22	6.1		9,002

Schedule of stock-based compensation expense related to stock options

	Year Ended December 31,
	2021		2020		2019
Research and development	$	3,750	$	1,514	$	2,312
Selling and marketing		4,014		1,719		1,013
General and administrative		7,214		4,298		5,434
	$	14,978	$	7,531	$	8,759