Exhibit23.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in the following Registration Statements:

a.Registration Statement (Form S-8 No. 333-147830) pertaining to the Amended and Restated 2003 Incentive Compensation Plan and the 2007 Equity Incentive Plan,

b.Registration Statement (Form S-8 No. 333-159132) pertaining to the 2007 Equity Incentive Plan,

c.Registration Statement (Form S-8 No. 333-165436) pertaining to the 2007 Equity Incentive Plan,

d.Registration Statement (Form S-8 No. 333-176760) pertaining to the 2007 Equity Incentive Plan,

e.Registration Statement (Form S-8 No. 333-181280) pertaining to the 2007 Equity Incentive Plan,

f.Registration Statement (Form S-8 No. 333-187052) pertaining to the 2007 Equity Incentive Plan,

g.Registration Statement (Form S-8 No. 333-190572) pertaining to the 2013 Employee Stock Purchase Plan,

h.Registration Statement (Form S-8 No. 333-194143) pertaining to the 2007 Equity Incentive Plan,

i.Registration Statement (Form S-8 No. 333-202144) pertaining to the 2007 Equity Incentive Plan,

j.Registration Statement (Form S-8 No. 333-209537) pertaining to the 2007 Equity Incentive Plan,

k.Registration Statement (Form S-8 No. 333-216142) pertaining to the Amended and Restated 2007 Equity Incentive Plan,

l.Registration Statement (Form S-8 No. 333-222942) pertaining to the Amended and Restated 2007 Equity Incentive Plan,

m.Registration Statement (Form S-8 No. 333-229475) pertaining to the Amended and Restated 2007 Equity Incentive Plan,

n.Registration Statement (Form S-8 No. 333-231194) pertaining to the 2013 Employee Stock Purchase Plan, As Amended,

o.Registration Statement (Form S-8 No. 333-236171) pertaining to the Amended and Restated 2007 Equity Incentive Plan,

p.Registration Statement (Form S-8 No. 333-253058) pertaining to the Amended and Restated 2007 Equity Incentive Plan,

q.Registration Statement (Form S-8 No. 333-260032) pertaining to the Moov Corporation 2017 Equity Incentive Plan,

r.Registration Statement (Form S-8 No. 333-260817) pertaining to the Limelight Networks, Inc. 2021 Inducement Plan,

s.Registration Statement (Form S-8 No. 333-262828) pertaining to the Amended and Restated 2007 Equity Incentive Plan,

t.Registration Statement (Form S-8 No. 333-269117) pertaining to the Amended and Restated 2007 Equity Incentive Plan,;

of our reports dated June 29, 2023, with respect to the consolidated financial statements and schedule of Edgio, Inc., and the effectiveness of internal control over financial reporting of Edgio, Inc., included in this Annual Report (Form 10-K) for the year ended December 31, 2022.

/s/ Ernst & Young LLP

Phoenix, Arizona

June 29, 2023