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Stock Based Compensation (Tables)
3 Months Ended
Mar. 31, 2017
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Allocated Stock-based Compensation Expense
The following table summarizes the components of stock-based compensation expense in the condensed consolidated statements of operations for the three months ended March 31, 2017 and 2016, respectively (in thousands):

 
Three Months Ended March 31,
 
2017
 
2016
Research and development
$
38

 
$
127

General and administrative
190

 
529

Total stock-based compensation from continuing operations
$
228

 
$
656

Assumptions for Option Grants Issued
The Company uses the Black-Scholes option-pricing model and the following weighted-average assumptions to determine the fair value of all its stock options granted:
 
 
Three Months Ended March 31,
 
2017
 
2016
Risk free interest rate
2.01
%
 
1.41
%
Volatility
108.55
%
 
75.24
%
Expected lives (years)
6.13

 
6.25

Expected dividend yield
%
 
%
Stock Option Activity
The following table summarizes stock option activity of the Company for the three months ended March 31, 2017:

 
Total
Number of
Shares
(In Thousands)
 
Weighted
Average
Exercise
Price
 
Aggregate
Intrinsic
Value
(In Thousands)
Outstanding at January 1, 2017
561

 
$
41.50

 


Granted
70

 
1.75

 


Exercised

 

 
$

Canceled
(73
)
 
32.59

 
$

Outstanding at March 31, 2017
558

 
$
37.68

 
$

Options exercisable at March 31, 2017
356

 
$
52.96

 
$