CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016
Cash flows from operating activities:
Net loss	$ (23,754)	$ (17,681)
Adjustment to reconcile net loss to net cash used in operating activities:
Depreciation and amortization expense		3
Non-cash research and development expense	258	821
Non-cash interest		1,166
Stock-based compensation	3,169	354
Loss on extinguishment of debt		201
Fair value of shares issued in exchange for research and development	449	1,974
Fair value of shares issued for incentive fee to Equilibria	941
Deferred income taxes		(41)
Severance costs paid by Galena	1,883
Changes in operating assets and liabilities:
Prepaid expenses and other assets	73	(477)
Accounts payable	8,366
Accrued expenses and other current liabilities	(2,374)	1,830
Net cash used in operating activities	(10,989)	(11,850)
Cash flows from investing activities:
Net cash acquired from acquisition of Galena	1,812
Change in restricted cash		(85)
Net cash provided by (used in) investing activities	1,812	(85)
Cash flows from financing activities:
Net proceeds from issuance of common stock	6,007
Net proceeds from issuance of convertible debt		15,000
Net proceeds from issuance of long-term debt		1,500
Principal payments on convertible debt	(473)
Net cash provided by financing activities	5,534	16,500
Net decrease (increase) in cash and cash equivalents	(3,643)	4,565
Cash and cash equivalents at the beginning of period	5,962	1,397
Cash and cash equivalents at end of period	2,319	$ 5,962
Supplemental disclosure of non-cash investing and financing activities:
Shares issued in connection with acquisition of Galena	12,487
Fair value of options assumed in connection with acquisition of Galena	32
Related party payable settled in shares	228
MSK payable settled in shares	150
Deemed dividend associated with conversion of 2015 Sely Note and common stock warrant issuance to Equilibria	675
2015 Shareholder Notes
Supplemental disclosure of non-cash investing and financing activities:
Shares issued upon conversion of notes and accrued interest	1,294
2015 Sely Note
Supplemental disclosure of non-cash investing and financing activities:
Shares issued upon conversion of notes and accrued interest	$ 6,064