Note 12 - Stockholders' Equity (Details Textual)						2 Months Ended	3 Months Ended		6 Months Ended		12 Months Ended
	May 01, 2023 USD ($) $ / shares shares	Apr. 27, 2023 USD ($) $ / shares	Nov. 15, 2022 $ / shares	Sep. 09, 2022 USD ($) $ / shares shares	Oct. 29, 2021 USD ($) $ / shares shares	Jun. 30, 2023 USD ($) $ / shares shares	Jun. 30, 2023 USD ($) $ / shares shares	Jun. 30, 2022 USD ($)	Jun. 30, 2023 USD ($) $ / shares shares	Jun. 30, 2022 USD ($)	Dec. 31, 2019 shares	Apr. 30, 2023 USD ($) $ / shares shares	Apr. 26, 2023 USD ($)	Dec. 31, 2022 $ / shares shares	Nov. 10, 2022 USD ($)	Sep. 08, 2022 USD ($) $ / shares	Jan. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Jan. 15, 2021 $ / shares shares	Sep. 30, 2020 $ / shares	Jul. 31, 2020 $ / shares
Common Stock, Shares Authorized (in shares)						150,000,000	150,000,000		150,000,000					150,000,000
Preferred Stock, Shares Authorized (in shares)						5,000,000	5,000,000		5,000,000					5,000,000
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares						$ 2.18	$ 2.18		$ 2.18					$ 7.70
Fair Value Adjustment of Warrants | $							$ (216,000)	$ (0)	$ (216,000)	$ (2,056,000)
Class of Warrant or Right, Issued During Period (in shares)									5,076,000
The 2022 Private Placement [Member]
Proceeds from Issuance or Sale of Equity, Total | $				$ 3,200,000
The 2022 Private Placement [Member] | Conversion of Series C Preferred Stock to Common Stock [Member]
Preferred Stock, Convertible, Shares Issuable (in shares)				516,750
The 2021 Private Placement Program [Member] | Conversion of Series B Preferred Stock to Common Stock [Member] | Stock Restatement From Reverse Stock Split [Member]
Preferred Stock, Convertible, Shares Issuable (in shares)					1,071,429
Series C Preferred Stock [Member]
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares		$ 6.30
Preferred Stock, Shares Outstanding (in shares)						1,000	1,000		1,000					2,000
Series C Preferred Stock [Member] | The 2022 Private Placement [Member]
Stock Issued During Period, Shares, New Issues (in shares)				3,250
Preferred Stock, Purchase Price (in dollars per share) | $ / shares				$ 1,000
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares				$ 6.30
Preferred Stock, Convertible, Conversion Ratio				159
Series C Preferred Stock [Member] | The 2023 Private Placement [Member]
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares						$ 1.30	$ 1.30		$ 1.30
Preferred Stock, Convertible, Conversion Ratio		770				770	770		770
Preferred Stock, Change in Conversion Price, Income Statement Impact | $		$ 194,000
Preferred Stock, Fair Value Disclosure | $						$ 1,100,000	$ 1,100,000		$ 1,100,000				$ 900,000
Conversion of Stock, Shares Converted (in shares)						2,153
Preferred Stock, Shares Outstanding (in shares)						1,097	1,097		1,097
Series B Preferred Stock [Member]
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares		$ 6.30	$ 6.30	$ 0.18												$ 0.40
Preferred Stock, Convertible, Conversion Ratio			159
Preferred Stock, Change in Conversion Price, Income Statement Impact | $				$ 5,700,000
Preferred Stock, Fair Value Disclosure | $				$ 12.5												$ 6,800,000
Preferred Stock, Shares Outstanding (in shares)						9,000	9,000		9,000					12,000
Convertible Preferred Stock, Shares Issued upon Conversion (in shares)				5,556
Series B Preferred Stock [Member] | The 2023 Private Placement [Member]
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares		$ 1.30
Preferred Stock, Convertible, Conversion Ratio		770
Preferred Stock, Change in Conversion Price, Income Statement Impact | $		$ 1,800,000
Preferred Stock, Fair Value Disclosure | $						$ 10,500,000	$ 10,500,000		$ 10,500,000				8,700,000
Conversion of Stock, Shares Converted (in shares)						5,844
Preferred Stock, Shares Outstanding (in shares)						9,156	9,156		9,156
Series B Preferred Stock [Member] | The 2021 Private Placement Program [Member]
Stock Issued During Period, Shares, New Issues (in shares)					15,000
Preferred Stock, Purchase Price (in dollars per share) | $ / shares					$ 1,000
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares					$ 0.40
Preferred Stock, Convertible, Conversion Ratio					2,500
Proceeds from Issuance of Preferred Stock and Preference Stock | $					$ 14,900,000
Certain Previously Issued Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)												1,724,455
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 1.50											$ 6.30
The Amended November 2021 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)				803,574
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares				$ 6.30
Warrants and Rights Outstanding | $				$ 3,500,000
Amended November 2021 Warrants Exercisable for 1.50 [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	535,716
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 1.50
Amended November 2021 Warrants Exercisable for 6.50 [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	267,858
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 6.30
The Amended July 2020 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	77,145
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 1.50
The July 2020 and November 2021 Warrants [Member]
Gain (Loss) on Modification of Warrants | $	$ 1,900,000
Warrants and Rights Outstanding | $	$ 5,200,000											$ 3,300,000
September 2022 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)						327,860	327,860		327,860
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares				$ 0.18
Warrants and Rights Outstanding | $				$ 1,400,000		$ 94,000	$ 94,000		$ 94,000				48,000		$ 500,000
Fair Value Adjustment of Warrants | $									$ 46,000
The November 2021 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)						803,574	803,574		803,574
Warrants and Rights Outstanding | $						$ 230,000	$ 230,000		$ 230,000				112,000		1,300,000		$ 7,500,000	$ 9,600,000
Fair Value Adjustment of Warrants | $									$ 117,000
Proceeds from Warrant Exercises | $				$ 700,000
The November 2021 Warrants [Member] | Stock Restatement From Reverse Stock Split [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares				$ 6.30
Amended July 2020 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)						77,145	77,145		77,145
Warrants and Rights Outstanding | $				$ 300,000											$ 100,000
Proceeds from Warrant Exercises | $				1,400,000
September 2022 Warrants Exercisable for 1.50 [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	238,574
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 1.50
September 2022 Warrants Exercisable for 6.50 [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	89,286
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 6.30
The 2022 Warrant Reprice Transaction [Member]
Proceeds from Warrant Exercises | $				2,100,000
Payments of Stock Issuance Costs | $				529,000
Payments of Stock Issuance Costs Allocated to Warrants | $				166,000
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs | $				$ 363,000
The 2022 Warrant Reprice Transaction [Member] | Ladenburg Thalmann and Co. Inc. [Member]
Exercise of Warrants, Commission, Percent				8.00%
The 2022 Private Placement Short Term Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)				515,876
The 2022 Private Placement Long Term Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)				515,876
The 2022 Private Placement Long Term Warrants Exercisable for 1.50 [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	873,020
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 1.50
The 2022 Private Placement Long Term Warrants Exercisable for 6.50 [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	158,732
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 6.30
May 2023 Warrants [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares		$ 1.30
Warrants and Rights Outstanding | $	$ 1,600,000					$ 1,400,000	$ 1,400,000		$ 1,400,000
Fair Value Adjustment of Warrants | $									$ 216,000
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares		$ 1.30
Series A-1 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)						515,876	515,876		515,876
Series A-2 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)						515,876	515,876		515,876
Series A-1 Warrants and Series A-2 Warrants [Member]
Warrants and Rights Outstanding | $						$ 216,000	$ 216,000		$ 216,000				$ 93,000
Fair Value Adjustment of Warrants | $									$ 122,000
The 2021 Warrants [Member] | Stock Restatement From Reverse Stock Split [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)					1,071,429
The 2019 Ladenburg Warrants [Member] | Stock Restatement From Reverse Stock Split [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares																				$ 34.65
Class of Warrant or Right, Issued During Period (in shares)											4,799
The July 2020 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)						59,960	59,960		59,960
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares																					$ 57.75
TLF Bio Innovation 2021 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)																			429
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares																			$ 23.51
Reverse Stock Split [Member]
Stockholders' Equity Note, Stock Split, Conversion Ratio			35