Note 16 - License, Collaboration and Distribution Agreements - Changes in Assets and Liabilities (Details) $ in Thousands	6 Months Ended
	Jun. 30, 2022 USD ($)
Contract Liabilities: Deferred Revenue, Balance at beginning of the period	$ 2
Contract Liabilities: Deferred Revenue, additions	69
Contract Liabilities: Deferred Revenue, deductions	(2)
Contract Liabilities: Deferred Revenue, Balance at the end of the period	69
Contract Liabilities: Accrued Liabilities,Balance at beginning of the period	1,270
Contract Liabilities: Accrued Liabilities, additions	1,357
Contract Liabilities: Accrued Liabilities, deductions	(1,167)
Contract Liabilities: Accrued Liabilities, Balance at the end of the period	1,460
Contract Liabilities, Balance at beginning of the period	1,272
Contract Liabilities, additions	1,426
Contract Liabilities, deductions	(1,169)
Contract Liabilities, Balance at the end of the period	$ 1,529